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247 related items for PubMed ID: 7748182

  • 1. Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved.
    White IN, De Matteis F, Gibbs AH, Lim CK, Wolf CR, Henderson C, Smith LL.
    Biochem Pharmacol; 1995 Apr 18; 49(8):1035-42. PubMed ID: 7748182
    [Abstract] [Full Text] [Related]

  • 2. Induction of CYP2B1 and 3A1, and associated monoxygenase activities by tamoxifen and certain analogues in the livers of female rats and mice.
    White IN, Davies A, Smith LL, Dawson S, De Matteis F.
    Biochem Pharmacol; 1993 Jan 07; 45(1):21-30. PubMed ID: 8424814
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  • 3. Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
    Mani C, Pearce R, Parkinson A, Kupfer D.
    Carcinogenesis; 1994 Dec 07; 15(12):2715-20. PubMed ID: 8001226
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  • 4. Effect of tamoxifen feeding on metabolic activation of tamoxifen by the liver of the rhesus monkey: does liver accumulation of inhibitory metabolites protect from tamoxifen-dependent genotoxicity and cancer?
    Comoglio A, Gibbs AH, White IN, Gant T, Martin EA, Smith LL, Gamalero SR, DeMatteis F.
    Carcinogenesis; 1996 Aug 07; 17(8):1687-93. PubMed ID: 8761427
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the NADPH-dependent covalent binding of [14C]halothane to human liver microsomes: a role for cytochrome P4502E1 at low substrate concentrations.
    Madan A, Parkinson A.
    Drug Metab Dispos; 1996 Dec 07; 24(12):1307-13. PubMed ID: 8971135
    [Abstract] [Full Text] [Related]

  • 6. In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.
    Saghir SA, Zhang F, Rick DL, Kan L, Bus JS, Bartels MJ.
    Regul Toxicol Pharmacol; 2010 Dec 07; 57(2-3):129-35. PubMed ID: 20096743
    [Abstract] [Full Text] [Related]

  • 7. Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.
    Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.
    Chem Res Toxicol; 1996 Dec 07; 9(8):1249-56. PubMed ID: 8951226
    [Abstract] [Full Text] [Related]

  • 8. Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation.
    Mani C, Kupfer D.
    Cancer Res; 1991 Nov 15; 51(22):6052-8. PubMed ID: 1933868
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  • 11. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ, Follansbee MH, Bond JA.
    Carcinogenesis; 1995 Oct 15; 16(10):2287-93. PubMed ID: 7586124
    [Abstract] [Full Text] [Related]

  • 12. Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites.
    den Besten C, Smink MC, de Vries EJ, van Bladeren PJ.
    Toxicol Appl Pharmacol; 1991 Apr 15; 108(2):223-33. PubMed ID: 2017752
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  • 13. Covalent binding of 14C- and 35S-labeled thiocarbamides in rat hepatic microsomes.
    Decker CJ, Doerge DR.
    Biochem Pharmacol; 1992 Feb 18; 43(4):881-8. PubMed ID: 1371686
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  • 14. Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes.
    Suzuki T, Fujita S, Narimatsu S, Masubuchi Y, Tachibana M, Ohta S, Hirobe M.
    FASEB J; 1992 Jan 06; 6(2):771-6. PubMed ID: 1537468
    [Abstract] [Full Text] [Related]

  • 15. Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
    Masubuchi Y, Araki J, Narimatsu S, Suzuki T.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2551-7. PubMed ID: 1632813
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  • 16. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug 23; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 17. Evaluation of monooxygenase induction as a means of enhancing the yield of the rat liver cytochrome P-450 isoenzyme with high affinity for cimetidine.
    Ioannoni B, Reilly PE, Winzor DJ.
    Biochem Pharmacol; 1983 Oct 15; 32(20):3103-8. PubMed ID: 6639678
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  • 19. Effect of inducers of cytochrome P-450 on the metabolism of [3-14C]coumarin by rat hepatic microsomes.
    Peters MM, Walters DG, van Ommen B, van Bladeren PJ, Lake BG.
    Xenobiotica; 1991 Apr 15; 21(4):499-514. PubMed ID: 1897250
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  • 20. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C, Gelboin HV, Park SS, Pearce R, Parkinson A, Kupfer D.
    Drug Metab Dispos; 1993 Apr 15; 21(4):645-56. PubMed ID: 8104124
    [Abstract] [Full Text] [Related]

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