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748 related items for PubMed ID: 7759993

  • 1. Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.
    Kisielow P, Miazek A.
    J Exp Med; 1995 Jun 01; 181(6):1975-84. PubMed ID: 7759993
    [Abstract] [Full Text] [Related]

  • 2. Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages.
    Crompton T, Lees RK, Pircher H, MacDonald HR.
    Proc Natl Acad Sci U S A; 1993 Oct 01; 90(19):8982-6. PubMed ID: 8415641
    [Abstract] [Full Text] [Related]

  • 3. CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection.
    Hare KJ, Jenkinson EJ, Anderson G.
    J Immunol; 1999 Apr 01; 162(7):3978-83. PubMed ID: 10201918
    [Abstract] [Full Text] [Related]

  • 4. Intrathymic maturation of murine T lymphocytes from CD8+ precursors.
    Guidos CJ, Weissman IL, Adkins B.
    Proc Natl Acad Sci U S A; 1989 Oct 01; 86(19):7542-6. PubMed ID: 2508090
    [Abstract] [Full Text] [Related]

  • 5. Opposite CD4/CD8 lineage decisions of CD4+8+ mouse and rat thymocytes to equivalent triggering signals: correlation with thymic expression of a truncated CD8 alpha chain in mice but not rats.
    Mitnacht R, Bischof A, Torres-Nagel N, Hünig T.
    J Immunol; 1998 Jan 15; 160(2):700-7. PubMed ID: 9551905
    [Abstract] [Full Text] [Related]

  • 6. TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.
    Yasutomo K, Lucas B, Germain RN.
    J Immunol; 2000 Sep 15; 165(6):3015-22. PubMed ID: 10975810
    [Abstract] [Full Text] [Related]

  • 7. The final maturation of at least some single-positive CD4(hi) thymocytes does not require T cell receptor-major histocompatibility complex contact.
    Dyall R, Nikolic-Zugić J.
    J Exp Med; 1999 Sep 20; 190(6):757-64. PubMed ID: 10499914
    [Abstract] [Full Text] [Related]

  • 8. Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and parallels other indicators of positive selection.
    Kearse KP, Takahama Y, Punt JA, Sharrow SO, Singer A.
    J Exp Med; 1995 Jan 01; 181(1):193-202. PubMed ID: 7528767
    [Abstract] [Full Text] [Related]

  • 9. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection.
    Yamashita I, Nagata T, Tada T, Nakayama T.
    Int Immunol; 1993 Sep 01; 5(9):1139-50. PubMed ID: 7902130
    [Abstract] [Full Text] [Related]

  • 10. In vitro maturation of clonal CD4+CD8+ cell lines in response to TCR engagement.
    Groves T, Katis P, Madden Z, Manickam K, Ramsden D, Wu G, Guidos CJ.
    J Immunol; 1995 May 15; 154(10):5011-22. PubMed ID: 7730608
    [Abstract] [Full Text] [Related]

  • 11. TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis.
    Groves T, Parsons M, Miyamoto NG, Guidos CJ.
    J Immunol; 1997 Jan 01; 158(1):65-75. PubMed ID: 8977176
    [Abstract] [Full Text] [Related]

  • 12. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 13. Self-specific MHC class II-restricted CD4-CD8- T cells that escape deletion and lack regulatory activity.
    Viret C, Janeway CA.
    J Immunol; 2003 Jan 01; 170(1):201-9. PubMed ID: 12496401
    [Abstract] [Full Text] [Related]

  • 14. Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection.
    Dutz JP, Ong CJ, Marth J, Teh HS.
    J Immunol; 1995 Mar 15; 154(6):2588-99. PubMed ID: 7533178
    [Abstract] [Full Text] [Related]

  • 15. Positive selection of thymocytes expressing the same TCR by different MHC ligands results in the production of functionally distinct thymocytes distinguished by differential expression of the heat stable antigen.
    Teh HS, Motyka B, Teh SJ.
    J Immunol; 1998 Jan 15; 160(2):718-27. PubMed ID: 9551907
    [Abstract] [Full Text] [Related]

  • 16. Disruption of intrathymic CD4-Ia interactions on immature CD4+CD8+ thymocytes results in diminished TCR expression on mature CD8+ T cell progeny.
    Roberts JL, Sharrow SO, Singer A.
    Cell Immunol; 1995 Mar 15; 161(1):22-7. PubMed ID: 7867081
    [Abstract] [Full Text] [Related]

  • 17. Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection.
    Anderson G, Hare KJ, Platt N, Jenkinson EJ.
    Eur J Immunol; 1997 Aug 15; 27(8):1838-42. PubMed ID: 9295015
    [Abstract] [Full Text] [Related]

  • 18. Generation of mature T cell populations in the thymus: CD4 or CD8 down-regulation occurs at different stages of thymocyte differentiation.
    Marodon G, Rocha B.
    Eur J Immunol; 1994 Jan 15; 24(1):196-204. PubMed ID: 7912676
    [Abstract] [Full Text] [Related]

  • 19. The quantity of TCR signal determines positive selection and lineage commitment of T cells.
    Watanabe N, Arase H, Onodera M, Ohashi PS, Saito T.
    J Immunol; 2000 Dec 01; 165(11):6252-61. PubMed ID: 11086060
    [Abstract] [Full Text] [Related]

  • 20. Intrathymic T cell receptor (TcR) targeting in mice lacking CD4 or major histocompatibility complex (MHC) class II: rescue of CD4 T cell lineage without co-engagement of TcR/CD4 by MHC class II.
    Müller KP, Kyewski BA.
    Eur J Immunol; 1995 Apr 01; 25(4):896-902. PubMed ID: 7737291
    [Abstract] [Full Text] [Related]

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