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Journal Abstract Search

269 related items for PubMed ID: 7763308

  • 1. Role of cytochrome P450 2C9 and an allelic variant in the 4'-hydroxylation of (R)- and (S)-flurbiprofen.
    Tracy TS, Rosenbluth BW, Wrighton SA, Gonzalez FJ, Korzekwa KR.
    Biochem Pharmacol; 1995 May 11; 49(9):1269-75. PubMed ID: 7763308
    [Abstract] [Full Text] [Related]

  • 2. Studies of flurbiprofen 4'-hydroxylation. Additional evidence suggesting the sole involvement of cytochrome P450 2C9.
    Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1305-9. PubMed ID: 8937439
    [Abstract] [Full Text] [Related]

  • 3. Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.
    Hamman MA, Thompson GA, Hall SD.
    Biochem Pharmacol; 1997 Jul 01; 54(1):33-41. PubMed ID: 9296349
    [Abstract] [Full Text] [Related]

  • 4. Comparative studies on the catalytic roles of cytochrome P450 2C9 and its Cys- and Leu-variants in the oxidation of warfarin, flurbiprofen, and diclofenac by human liver microsomes.
    Yamazaki H, Inoue K, Chiba K, Ozawa N, Kawai T, Suzuki Y, Goldstein JA, Guengerich FP, Shimada T.
    Biochem Pharmacol; 1998 Jul 15; 56(2):243-51. PubMed ID: 9698079
    [Abstract] [Full Text] [Related]

  • 5. Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs.
    Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong NT, Battioni P, Dansette PM, Mansuy D.
    Biochemistry; 1999 Oct 26; 38(43):14264-70. PubMed ID: 10572000
    [Abstract] [Full Text] [Related]

  • 6. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
    [Abstract] [Full Text] [Related]

  • 7. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.
    J Pharmacol Exp Ther; 2000 May 01; 293(2):453-9. PubMed ID: 10773015
    [Abstract] [Full Text] [Related]

  • 8. Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation.
    Tracy TS, Marra C, Wrighton SA, Gonzalez FJ, Korzekwa KR.
    Eur J Clin Pharmacol; 1997 May 01; 52(4):293-8. PubMed ID: 9248768
    [Abstract] [Full Text] [Related]

  • 9. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
    Yamazaki H, Shaw PM, Guengerich FP, Shimada T.
    Chem Res Toxicol; 1998 Jun 01; 11(6):659-65. PubMed ID: 9625734
    [Abstract] [Full Text] [Related]

  • 10. Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
    Giancarlo GM, Venkatakrishnan K, Granda BW, von Moltke LL, Greenblatt DJ.
    Eur J Clin Pharmacol; 2001 Apr 01; 57(1):31-6. PubMed ID: 11372587
    [Abstract] [Full Text] [Related]

  • 11. Roles of two allelic variants (Arg144Cys and Ile359Leu) of cytochrome P4502C9 in the oxidation of tolbutamide and warfarin by human liver microsomes.
    Yamazaki H, Inoue K, Shimada T.
    Xenobiotica; 1998 Feb 01; 28(2):103-15. PubMed ID: 9522436
    [Abstract] [Full Text] [Related]

  • 12. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY, Li W, Traeger SC, Wang B, Cui D, Zhang H, Wen B, Rodrigues AD.
    Drug Metab Dispos; 2008 Dec 01; 36(12):2513-22. PubMed ID: 18787056
    [Abstract] [Full Text] [Related]

  • 13. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H, Shimada T.
    Arch Biochem Biophys; 1997 Oct 01; 346(1):161-9. PubMed ID: 9328296
    [Abstract] [Full Text] [Related]

  • 14. Cytochrome P4502C9 is the principal catalyst of racemic acenocoumarol hydroxylation reactions in human liver microsomes.
    Thijssen HH, Flinois JP, Beaune PH.
    Drug Metab Dispos; 2000 Nov 01; 28(11):1284-90. PubMed ID: 11038154
    [Abstract] [Full Text] [Related]

  • 15. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb 01; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 16. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N, Oda Y, Hase I, Asada A.
    Br J Anaesth; 2001 Apr 01; 86(4):540-4. PubMed ID: 11573629
    [Abstract] [Full Text] [Related]

  • 17. Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes.
    Crewe HK, Ellis SW, Lennard MS, Tucker GT.
    Biochem Pharmacol; 1997 Jan 24; 53(2):171-8. PubMed ID: 9037249
    [Abstract] [Full Text] [Related]

  • 18. Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4.
    Chesné C, Guyomard C, Guillouzo A, Schmid J, Ludwig E, Sauter T.
    Xenobiotica; 1998 Jan 24; 28(1):1-13. PubMed ID: 9493314
    [Abstract] [Full Text] [Related]

  • 19. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.
    Chem Res Toxicol; 1999 Feb 24; 12(2):192-9. PubMed ID: 10027798
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone.
    Baldwin SJ, Clarke SE, Chenery RJ.
    Br J Clin Pharmacol; 1999 Sep 24; 48(3):424-32. PubMed ID: 10510156
    [Abstract] [Full Text] [Related]

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