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138 related items for PubMed ID: 7779086

  • 1. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain.
    Zhang ML, Sugawa H, Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1995 Jun 06; 211(1):205-10. PubMed ID: 7779086
    [Abstract] [Full Text] [Related]

  • 2. Constitutive activation of the thyrotropin receptor by mutating CYS-636 in the sixth transmembrane segment.
    Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1996 May 24; 222(3):713-7. PubMed ID: 8651910
    [Abstract] [Full Text] [Related]

  • 3. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
    Neumann S, Krohn K, Chey S, Paschke R.
    Horm Metab Res; 2001 May 24; 33(5):263-9. PubMed ID: 11440271
    [Abstract] [Full Text] [Related]

  • 4. The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor.
    Rossi M, Dimida A, Dell'anno MT, Trincavelli ML, Agretti P, Giorgi F, Corsini GU, Pinchera A, Vitti P, Tonacchera M, Maggio R.
    J Pharmacol Exp Ther; 2007 Jan 24; 320(1):465-74. PubMed ID: 17062616
    [Abstract] [Full Text] [Related]

  • 5. Oncogenic potential of a mutant human thyrotropin receptor expressed in FRTL-5 cells.
    Fournes B, Monier R, Michiels F, Milgrom E, Misrahi M, Feunteun J.
    Oncogene; 1998 Feb 26; 16(8):985-90. PubMed ID: 9519872
    [Abstract] [Full Text] [Related]

  • 6. Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance.
    Calebiro D, de Filippis T, Lucchi S, Covino C, Panigone S, Beck-Peccoz P, Dunlap D, Persani L.
    Hum Mol Genet; 2005 Oct 15; 14(20):2991-3002. PubMed ID: 16135555
    [Abstract] [Full Text] [Related]

  • 7. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I, Lima L, Seoane R, Lado-Abeal J.
    Thyroid; 2009 Jun 15; 19(6):645-9. PubMed ID: 19499991
    [Abstract] [Full Text] [Related]

  • 8. Mutations of thyrotropin receptor isolated from thyroid autonomous functioning adenomas confer TSH-independent growth to thyroid cells.
    Porcellini A, Ruggiano G, Pannain S, Ciullo I, Amabile G, Fenzi G, Avvedimento EV.
    Oncogene; 1997 Aug 14; 15(7):781-9. PubMed ID: 9266964
    [Abstract] [Full Text] [Related]

  • 9. Constitutive activation of cyclic AMP but not phosphatidylinositol signaling caused by four mutations in the 6th transmembrane helix of the human thyrotropin receptor.
    Kosugi S, Shenker A, Mori T.
    FEBS Lett; 1994 Dec 19; 356(2-3):291-4. PubMed ID: 7805857
    [Abstract] [Full Text] [Related]

  • 10. Identification of TSH receptor mutations in three families with resistance to TSH.
    Tonacchera M, Di Cosmo C, De Marco G, Agretti P, Banco M, Perri A, Gianetti E, Montanelli L, Vitti P, Pinchera A.
    Clin Endocrinol (Oxf); 2007 Nov 19; 67(5):712-8. PubMed ID: 17697008
    [Abstract] [Full Text] [Related]

  • 11. Thyrotropin stimulation of the lutropin/choriogonadotropin receptor: different sites mediate agonist activity and high affinity binding.
    Hidaka A, Ban T, Panesar NS, Minegishi T, Kohn LD, Tahara K.
    Thyroid; 1994 Nov 19; 4(4):447-57. PubMed ID: 7711510
    [Abstract] [Full Text] [Related]

  • 12. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.
    Mueller S, Jaeschke H, Paschke R.
    Methods Enzymol; 2010 Nov 19; 485():421-36. PubMed ID: 21050930
    [Abstract] [Full Text] [Related]

  • 13. Possible difference in glycosylation of the thyrotropin receptor among species.
    Kosugi S, Akamizu T, Mori T.
    Biochem Biophys Res Commun; 1994 May 16; 200(3):1207-13. PubMed ID: 8185569
    [Abstract] [Full Text] [Related]

  • 14. Thyrotropin, like luteinizing hormone (LH) and chorionic gonadotropin (CG), increases cAMP and inositol phosphate levels in cells with recombinant human LH/CG receptor.
    Hidaka A, Minegishi T, Kohn LD.
    Biochem Biophys Res Commun; 1993 Oct 15; 196(1):187-95. PubMed ID: 8216292
    [Abstract] [Full Text] [Related]

  • 15. Point mutations of the thyrotropin receptor determining structural requirements for its ability to bind thyrotropin and to stimulate adenylate cyclase activity.
    Gustavsson B, Westermark B, Heldin NE.
    Biochem Biophys Res Commun; 1994 Mar 15; 199(2):612-8. PubMed ID: 8135801
    [Abstract] [Full Text] [Related]

  • 16. Thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) prevents internalization of TSH receptor.
    Picchietti S, Belardinelli M, Taddei AR, Fausto AM, Pellegrino M, Maggio R, Rossi M, Giorgi F.
    Cell Tissue Res; 2009 Apr 15; 336(1):31-40. PubMed ID: 19214582
    [Abstract] [Full Text] [Related]

  • 17. Both the 5' and 3' noncoding regions of the thyrotropin receptor messenger ribonucleic acid influence the level of receptor protein expression in transfected mamalian cells.
    Kakinuma A, Chazenbalk G, Filetti S, McLachlan SM, Rapoport B.
    Endocrinology; 1996 Jul 15; 137(7):2664-9. PubMed ID: 8770884
    [Abstract] [Full Text] [Related]

  • 18. Evidence for negative cooperativity among human thyrotropin receptors overexpressed in mammalian cells.
    Chazenbalk GD, Kakinuma A, Jaume JC, McLachlan SM, Rapoport B.
    Endocrinology; 1996 Nov 15; 137(11):4586-91. PubMed ID: 8895321
    [Abstract] [Full Text] [Related]

  • 19. Recombinant thyrotropin stimulates cAMP formation in CHO-K1 cells expressing recombinant chorionic gonadotropin receptor.
    Gunji K, Endo T, Ohno M, Minegishi T, Onaya T.
    Biochem Biophys Res Commun; 1993 Dec 30; 197(3):1530-5. PubMed ID: 8280172
    [Abstract] [Full Text] [Related]

  • 20. The intracellular region adjacent to plasma membrane (residues 684-692) of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation.
    Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1994 Mar 30; 199(3):1497-503. PubMed ID: 8147896
    [Abstract] [Full Text] [Related]

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