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107 related items for PubMed ID: 7808589

  • 1. Lewis rat EAN is suppressed by the 21-aminosteroid tirilazad mesylate (U-74006F).
    Feasby TE, Hahn AF, Lovgren D, Wilkie L.
    Neuropathol Appl Neurobiol; 1994 Aug; 20(4):384-91. PubMed ID: 7808589
    [Abstract] [Full Text] [Related]

  • 2. The 21-aminosteroid tirilazad mesylate protects against liver injury via membrane stabilization not inhibition of lipid peroxidation.
    Wang Y, Mathews WR, Guido DM, Jaeschke H.
    J Pharmacol Exp Ther; 1996 May; 277(2):714-20. PubMed ID: 8627550
    [Abstract] [Full Text] [Related]

  • 3. Comparison of tirilazad mesylate (U-74006F) and methylprednisolone sodium succinate treatments in experimental allergic encephalomyelitis in the guinea pig.
    Karlik SJ, Stavraky RT, Hall ED.
    Mult Scler; 1996 Feb; 1(4):228-35. PubMed ID: 9345440
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  • 5. Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils.
    Hall ED, Pazara KE, Braughler JM.
    Stroke; 1991 Mar; 22(3):361-6. PubMed ID: 2003306
    [Abstract] [Full Text] [Related]

  • 6. Effects of the 21-amino steroid tirilazad mesylate (U-74006F) on brain damage and edema after perinatal hypoxia-ischemia in the rat.
    Bågenholm R, Andiné P, Hagberg H.
    Pediatr Res; 1996 Sep; 40(3):399-403. PubMed ID: 8865275
    [Abstract] [Full Text] [Related]

  • 7. Neuronal degeneration and iNOS expression in experimental brain contusion following treatment with colchicine, dexamethasone, tirilazad mesylate and nimodipine.
    Gahm C, Holmin S, Rudehill S, Mathiesen T.
    Acta Neurochir (Wien); 2005 Oct; 147(10):1071-84; discussion 1084. PubMed ID: 16044358
    [Abstract] [Full Text] [Related]

  • 8. Dose-response analysis of the effect of 21-aminosteroid tirilazad mesylate (U-74006F) upon neurological outcome and ischemic brain damage in permanent focal cerebral ischemia.
    Park CK, Hall ED.
    Brain Res; 1994 May 09; 645(1-2):157-63. PubMed ID: 8062078
    [Abstract] [Full Text] [Related]

  • 9. Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome.
    Smith SL, Hall ED.
    J Neurotrauma; 1998 Sep 09; 15(9):707-19. PubMed ID: 9753218
    [Abstract] [Full Text] [Related]

  • 10. Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury.
    Smith SL, Scherch HM, Hall ED.
    J Neurosurg; 1996 Feb 09; 84(2):229-33. PubMed ID: 8592225
    [Abstract] [Full Text] [Related]

  • 11. Effect of lipid peroxidation inhibition on retinal ganglion cell death.
    Levin LA, Clark JA, Johns LK.
    Invest Ophthalmol Vis Sci; 1996 Dec 09; 37(13):2744-9. PubMed ID: 8977490
    [Abstract] [Full Text] [Related]

  • 12. Cortical hypoperfusion following spreading depression is not altered by tirilazad mesylate (U-74006F) in awake rats.
    Duckrow RB, Beard DC.
    Brain Res; 1992 Feb 14; 572(1-2):296-9. PubMed ID: 1611527
    [Abstract] [Full Text] [Related]

  • 13. Demyelination and axonal degeneration in Lewis rat experimental allergic neuritis depend on the myelin dosage.
    Hahn AF, Feasby TE, Steele A, Lovgren DS, Berry J.
    Lab Invest; 1988 Jul 14; 59(1):115-25. PubMed ID: 3260639
    [Abstract] [Full Text] [Related]

  • 14. The 21-aminosteroid 16-desmethyl tirilazad mesylate prevents necroinflammatory changes in experimental alcoholic liver disease.
    Sadrzadeh SM, Nanji AA.
    J Pharmacol Exp Ther; 1998 Jan 14; 284(1):406-12. PubMed ID: 9435204
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of the pharmacokinetics and tolerability of tirilazad mesylate, a 21-aminosteroid free radical scavenger: I. Single-dose administration.
    Fleishaker JC, Peters GR, Cathcart KS.
    J Clin Pharmacol; 1993 Feb 14; 33(2):175-81. PubMed ID: 8382708
    [Abstract] [Full Text] [Related]

  • 16. Infant rat model of the shaken baby syndrome: preliminary characterization and evidence for the role of free radicals in cortical hemorrhaging and progressive neuronal degeneration.
    Smith SL, Andrus PK, Gleason DD, Hall ED.
    J Neurotrauma; 1998 Sep 14; 15(9):693-705. PubMed ID: 9753217
    [Abstract] [Full Text] [Related]

  • 17. Effect of tirilazad mesylate given after permanent middle cerebral artery occlusion in rat.
    Hellström HO, Wanhainen A, Valtysson J, Persson L, Hillered L.
    Acta Neurochir (Wien); 1994 Sep 14; 129(3-4):188-92. PubMed ID: 7847162
    [Abstract] [Full Text] [Related]

  • 18. Decreased red blood cells deformability in acute pancreatitis in the rat. Effect of tirilazad mesylate.
    Chmiel B, Pajak J, Grabowska-Bochenek R, Cierpka L.
    Folia Med Cracov; 2003 Sep 14; 44(1-2):109-15. PubMed ID: 15232892
    [Abstract] [Full Text] [Related]

  • 19. Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat.
    Smith SL, Andrus PK, Zhang JR, Hall ED.
    J Neurotrauma; 1994 Aug 14; 11(4):393-404. PubMed ID: 7837280
    [Abstract] [Full Text] [Related]

  • 20. Amelioration of impaired cerebral metabolism after severe acidotic ischemia by tirilazad posttreatment in dogs.
    Kim H, Koehler RC, Hurn PD, Hall ED, Traystman RJ.
    Stroke; 1996 Jan 14; 27(1):114-21. PubMed ID: 8553386
    [Abstract] [Full Text] [Related]

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