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164 related items for PubMed ID: 7838
21. Pharmacokinetics of the toxic hydrazino metabolites formed from isoniazid in humans. Lauterburg BH, Smith CV, Todd EL, Mitchell JR. J Pharmacol Exp Ther; 1985 Dec; 235(3):566-70. PubMed ID: 4078724 [Abstract] [Full Text] [Related]
23. Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydranize metabolites. Mitchell JR, Thorgeirsson UP, Black M, Timbrell JA, Snodgrass WR, Potter WZ, Jollow HR, Keiser HR. Clin Pharmacol Ther; 1975 Jul; 18(1):70-9. PubMed ID: 1149365 [Abstract] [Full Text] [Related]
24. Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model. Tafazoli S, Mashregi M, O'Brien PJ. Toxicol Appl Pharmacol; 2008 May 15; 229(1):94-101. PubMed ID: 18295292 [Abstract] [Full Text] [Related]
25. [Effects of ascorbic acid on the free radical formations of isoniazid and its metabolites]. Matsuki Y, Akazawa M, Tsuchiya K, Sakurai H, Kiwada H, Goromaru T. Yakugaku Zasshi; 1991 Oct 15; 111(10):600-5. PubMed ID: 1812280 [Abstract] [Full Text] [Related]
26. [Reactive metabolites of xenobiotics : their role in the hepatotoxicity of drugs]. Pessayre D, Benhamou JP. C R Seances Soc Biol Fil; 1979 Oct 15; 173(2):458-68. PubMed ID: 159767 [Abstract] [Full Text] [Related]
27. Enzymatic activation of hydrazine derivatives. A spin-trapping study. Sinha BK. J Biol Chem; 1983 Jan 25; 258(2):796-801. PubMed ID: 6296081 [Abstract] [Full Text] [Related]
28. Binding of toxic metabolites of isoniazid by aconiazide. Held HR, Landi S. J Pharm Sci; 1980 Nov 25; 69(11):1284-7. PubMed ID: 7452457 [Abstract] [Full Text] [Related]
29. Monoacetylhydrazine as a metabolite of isoniazid in man. Timbrell JA, Wright JM, Baillie TA. Clin Pharmacol Ther; 1977 Nov 25; 22(5 Pt 1):602-8. PubMed ID: 913027 [Abstract] [Full Text] [Related]
30. The role of oxygen free radicals in isoniazid-induced hepatotoxicity. Walubo A, Smith P, Folb PI. Methods Find Exp Clin Pharmacol; 1998 Oct 25; 20(8):649-55. PubMed ID: 9922980 [Abstract] [Full Text] [Related]
31. Inhibition of isoniazid-induced hepatotoxicity in rabbits by pretreatment with an amidase inhibitor. Sarich TC, Adams SP, Petricca G, Wright JM. J Pharmacol Exp Ther; 1999 May 25; 289(2):695-702. PubMed ID: 10215642 [Abstract] [Full Text] [Related]
32. Metabolism-dependent inhibition of CYP2E1 by isoniazid, a mediator of idiosyncratic liver injury. Masubuchi Y, Miyauchi K. Chem Biol Interact; 2024 Sep 01; 400():111160. PubMed ID: 39047805 [Abstract] [Full Text] [Related]
33. Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats. Metushi IG, Nakagawa T, Uetrecht J. Chem Res Toxicol; 2012 Nov 19; 25(11):2567-76. PubMed ID: 23016703 [Abstract] [Full Text] [Related]
34. Role of hydrazine in the mechanism of isoniazid hepatotoxicity in rabbits. Sarich TC, Youssefi M, Zhou T, Adams SP, Wall RA, Wright JM. Arch Toxicol; 1996 Nov 19; 70(12):835-40. PubMed ID: 8911642 [Abstract] [Full Text] [Related]
35. Factors affecting the metabolism of [14C]acetylhydrazine in rats. Wright JM, Timbrell JA. Drug Metab Dispos; 1978 Nov 19; 6(5):561-6. PubMed ID: 30606 [Abstract] [Full Text] [Related]
36. Effects of ascorbic acid on iproniazid-induced hepatitis in phenobarbital-treated rats. Matsuki Y, Bandou R, Kiwada H, Maeda H, Goromaru T. Biol Pharm Bull; 1994 Aug 19; 17(8):1078-82. PubMed ID: 7820112 [Abstract] [Full Text] [Related]
37. Metabolism of [14C]acetylisoniazid and [14C]acetylhydrazine by the rat and rabbit. Thomas BH, Whitehouse LW, Zeitz W. Fundam Appl Toxicol; 1984 Aug 19; 4(4):646-53. PubMed ID: 6479511 [Abstract] [Full Text] [Related]
38. More about isonicotinic acid hydrazide toxicity. Food Cosmet Toxicol; 1970 Oct 19; 8(5):578-9. PubMed ID: 4923938 [No Abstract] [Full Text] [Related]
39. Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1). Albano E, Comoglio A, Clot P, Iannone A, Tomasi A, Ingelman-Sundberg M. Biochim Biophys Acta; 1995 Apr 13; 1243(3):414-20. PubMed ID: 7727516 [Abstract] [Full Text] [Related]
40. Effects of rifampicin on pharmacokinetics of isoniazid and its metabolite acetylhydrazine in rats. Zhang RL, Wang ZY, Li D, Cheng WB. Zhongguo Yao Li Xue Bao; 1992 Nov 13; 13(6):494-6. PubMed ID: 1302435 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]