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172 related items for PubMed ID: 7839142

  • 1. Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.
    Strobel SA, Cech TR.
    Science; 1995 Feb 03; 267(5198):675-9. PubMed ID: 7839142
    [Abstract] [Full Text] [Related]

  • 2. Exocyclic amine of the conserved G.U pair at the cleavage site of the Tetrahymena ribozyme contributes to 5'-splice site selection and transition state stabilization.
    Strobel SA, Cech TR.
    Biochemistry; 1996 Jan 30; 35(4):1201-11. PubMed ID: 8573575
    [Abstract] [Full Text] [Related]

  • 3. Dissection of the role of the conserved G.U pair in group I RNA self-splicing.
    Knitt DS, Narlikar GJ, Herschlag D.
    Biochemistry; 1994 Nov 22; 33(46):13864-79. PubMed ID: 7947795
    [Abstract] [Full Text] [Related]

  • 4. Divalent metal ion binding to a conserved wobble pair defining the upstream site of cleavage of group I self-splicing introns.
    Allain FH, Varani G.
    Nucleic Acids Res; 1995 Feb 11; 23(3):341-50. PubMed ID: 7885828
    [Abstract] [Full Text] [Related]

  • 5. Replacement of the conserved G.U with a G-C pair at the cleavage site of the Tetrahymena ribozyme decreases binding, reactivity, and fidelity.
    Pyle AM, Moran S, Strobel SA, Chapman T, Turner DH, Cech TR.
    Biochemistry; 1994 Nov 22; 33(46):13856-63. PubMed ID: 7947794
    [Abstract] [Full Text] [Related]

  • 6. Probing the role of a secondary structure element at the 5'- and 3'-splice sites in group I intron self-splicing: the tetrahymena L-16 ScaI ribozyme reveals a new role of the G.U pair in self-splicing.
    Karbstein K, Lee J, Herschlag D.
    Biochemistry; 2007 Apr 24; 46(16):4861-75. PubMed ID: 17385892
    [Abstract] [Full Text] [Related]

  • 7. The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA.
    Strobel SA, Cech TR, Usman N, Beigelman L.
    Biochemistry; 1994 Nov 22; 33(46):13824-35. PubMed ID: 7524665
    [Abstract] [Full Text] [Related]

  • 8. Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.
    Legault P, Herschlag D, Celander DW, Cech TR.
    Nucleic Acids Res; 1992 Dec 25; 20(24):6613-9. PubMed ID: 1480482
    [Abstract] [Full Text] [Related]

  • 9. A shortened form of the Tetrahymena thermophila group I intron can catalyze the complete splicing reaction in trans.
    Sargueil B, Tanner NK.
    J Mol Biol; 1993 Oct 20; 233(4):629-43. PubMed ID: 8411170
    [Abstract] [Full Text] [Related]

  • 10. Identification of A-minor tertiary interactions within a bacterial group I intron active site by 3-deazaadenosine interference mapping.
    Soukup JK, Minakawa N, Matsuda A, Strobel SA.
    Biochemistry; 2002 Aug 20; 41(33):10426-38. PubMed ID: 12173929
    [Abstract] [Full Text] [Related]

  • 11. Mutations in the Tetrahymena ribozyme internal guide sequence: effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity.
    Campbell TB, Cech TR.
    Biochemistry; 1996 Sep 03; 35(35):11493-502. PubMed ID: 8784205
    [Abstract] [Full Text] [Related]

  • 12. Solution structure of a metal-binding site in the major groove of RNA complexed with cobalt (III) hexammine.
    Kieft JS, Tinoco I.
    Structure; 1997 May 15; 5(5):713-21. PubMed ID: 9195889
    [Abstract] [Full Text] [Related]

  • 13. Recognition of the T stem-loop of a pre-tRNA substrate by the ribozyme from Bacillus subtilis ribonuclease P.
    Loria A, Pan T.
    Biochemistry; 1997 May 27; 36(21):6317-25. PubMed ID: 9174346
    [Abstract] [Full Text] [Related]

  • 14. Tertiary interactions with the internal guide sequence mediate docking of the P1 helix into the catalytic core of the Tetrahymena ribozyme.
    Strobel SA, Cech TR.
    Biochemistry; 1993 Dec 14; 32(49):13593-604. PubMed ID: 7504953
    [Abstract] [Full Text] [Related]

  • 15. RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.
    Doudna JA, Cormack BP, Szostak JW.
    Proc Natl Acad Sci U S A; 1989 Oct 14; 86(19):7402-6. PubMed ID: 2678103
    [Abstract] [Full Text] [Related]

  • 16. A hydrogen-bonding triad stabilizes the chemical transition state of a group I ribozyme.
    Strobel SA, Ortoleva-Donnelly L.
    Chem Biol; 1999 Mar 14; 6(3):153-65. PubMed ID: 10074469
    [Abstract] [Full Text] [Related]

  • 17. Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site.
    Herschlag D, Cech TR.
    Biochemistry; 1990 Nov 06; 29(44):10159-71. PubMed ID: 2271645
    [Abstract] [Full Text] [Related]

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  • 19. Ribozyme catalysis from the major groove of group II intron domain 5.
    Konforti BB, Abramovitz DL, Duarte CM, Karpeisky A, Beigelman L, Pyle AM.
    Mol Cell; 1998 Feb 06; 1(3):433-41. PubMed ID: 9660927
    [Abstract] [Full Text] [Related]

  • 20. Mechanistic investigations of a ribozyme derived from the Tetrahymena group I intron: insights into catalysis and the second step of self-splicing.
    Mei R, Herschlag D.
    Biochemistry; 1996 May 07; 35(18):5796-809. PubMed ID: 8639540
    [Abstract] [Full Text] [Related]

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