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Journal Abstract Search

253 related items for PubMed ID: 7850779

  • 1.
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  • 2. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues.
    Miyachi H, Takemura Y, Kobayashi H, Ando K, Ando Y.
    Jpn J Cancer Res; 1993 Jan; 84(1):9-12. PubMed ID: 8449831
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  • 4. N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate.
    Takemura Y, Ohnuma T.
    Mt Sinai J Med; 1992 Oct; 59(5):419-24. PubMed ID: 1435841
    [Abstract] [Full Text] [Related]

  • 5. Specificity of ribozyme designed for mutated DHFR mRNA.
    Kobayashi H, Kim N, Halatsch ME, Ohnuma T.
    Biochem Pharmacol; 1994 Apr 29; 47(9):1607-13. PubMed ID: 8185675
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  • 6. Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugs.
    Takemura Y, Kobayashi H, Miyachi H, Gibson W, Kimbell R, Jackman AL.
    Jpn J Cancer Res; 1996 Jul 29; 87(7):773-80. PubMed ID: 8698629
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  • 8. Microsatellite instability and clonal heterogeneity of MDR1 messenger RNA expression in trimetrexate-resistant human leukemia MOLT-3 cells developed in thymidine.
    Miyachi H, Ma L, Takemura Y, Kobayashi H, Hirahara I, Sonehara H, Ando Y.
    Int J Cancer; 1999 Jul 02; 82(1):63-9. PubMed ID: 10360822
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  • 9. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H, Niethammer D, Jackson RC.
    Cancer Res; 1983 Nov 02; 43(11):5286-92. PubMed ID: 6225514
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  • 10. A human leukemia cell line made resistant to two folate analogues, trimetrexate and N10-propargyl-5,8-dideazafolic acid (CB3717).
    Takemura Y, Ohnuma T, Miyachi H, Sekiguchi S.
    J Cancer Res Clin Oncol; 1991 Nov 02; 117(6):519-25. PubMed ID: 1683871
    [Abstract] [Full Text] [Related]

  • 11. Multidrug resistance in a human leukemic cell line selected for resistance to trimetrexate.
    Arkin H, Ohnuma T, Kamen BA, Holland JF, Vallabhajosula S.
    Cancer Res; 1989 Dec 01; 49(23):6556-61. PubMed ID: 2573416
    [Abstract] [Full Text] [Related]

  • 12. Expression of dihydrofolate reductase and multidrug resistance genes in trimetrexate-resistant human leukemia cell lines.
    Li XK, Kobayashi H, Holland JF, Ohnuma T.
    Leuk Res; 1993 Jun 01; 17(6):483-90. PubMed ID: 8099375
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  • 13. Variable expression of the folylpolyglutamate synthetase gene at the level of mRNA transcription in human leukemia cell lines sensitive, or made resistant, to various antifolate drugs.
    Takemura Y, Kobayashi H, Miyachi H.
    Anticancer Drugs; 1999 Aug 01; 10(7):677-83. PubMed ID: 10507318
    [Abstract] [Full Text] [Related]

  • 14. Enzyme studies of methotrexate-resistant human leukemic cell (K562) subclones.
    Koizumi S, Allegra CJ.
    Leuk Res; 1992 Aug 01; 16(6-7):565-9. PubMed ID: 1378915
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  • 15. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
    Senkovich O, Schormann N, Chattopadhyay D.
    Acta Crystallogr D Biol Crystallogr; 2009 Jul 01; 65(Pt 7):704-16. PubMed ID: 19564691
    [Abstract] [Full Text] [Related]

  • 16. Molecular mechanism of antifolate transport-deficiency in a methotrexate-resistant MOLT-3 human leukemia cell line.
    Gong M, Yess J, Connolly T, Ivy SP, Ohnuma T, Cowan KH, Moscow JA.
    Blood; 1997 Apr 01; 89(7):2494-9. PubMed ID: 9116294
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  • 17. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate.
    Assaraf YG, Molina A, Schimke RT.
    J Biol Chem; 1989 Nov 05; 264(31):18326-34. PubMed ID: 2572592
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  • 18. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.
    Dixon KH, Trepel JB, Eng SC, Cowan KH.
    Cancer Commun; 1991 Nov 05; 3(12):357-65. PubMed ID: 16296001
    [Abstract] [Full Text] [Related]

  • 19. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
    Liani E, Rothem L, Bunni MA, Smith CA, Jansen G, Assaraf YG.
    Int J Cancer; 2003 Feb 20; 103(5):587-99. PubMed ID: 12494465
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  • 20. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
    Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, Bertino JR.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3400-5. PubMed ID: 11891321
    [Abstract] [Full Text] [Related]

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