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Journal Abstract Search

141 related items for PubMed ID: 7858182

  • 1. Humanization of the murine anti-human CD3 monoclonal antibody OKT3.
    Adair JR, Athwal DS, Bodmer MW, Bright SM, Collins AM, Pulito VL, Rao PE, Reedman R, Rothermel AL, Xu D.
    Hum Antibodies Hybridomas; 1994; 5(1-2):41-7. PubMed ID: 7858182
    [Abstract] [Full Text] [Related]

  • 2. Humanized OKT3 antibodies: successful transfer of immune modulating properties and idiotype expression.
    Woodle ES, Thistlethwaite JR, Jolliffe LK, Zivin RA, Collins A, Adair JR, Bodmer M, Athwal D, Alegre ML, Bluestone JA.
    J Immunol; 1992 May 01; 148(9):2756-63. PubMed ID: 1533410
    [Abstract] [Full Text] [Related]

  • 3. Human IgG2 variants of chimeric anti-CD3 are nonmitogenic to T cells.
    Cole MS, Anasetti C, Tso JY.
    J Immunol; 1997 Oct 01; 159(7):3613-21. PubMed ID: 9317161
    [Abstract] [Full Text] [Related]

  • 4. In vitro characterization of five humanized OKT3 effector function variant antibodies.
    Xu D, Alegre ML, Varga SS, Rothermel AL, Collins AM, Pulito VL, Hanna LS, Dolan KP, Parren PW, Bluestone JA, Jolliffe LK, Zivin RA.
    Cell Immunol; 2000 Feb 25; 200(1):16-26. PubMed ID: 10716879
    [Abstract] [Full Text] [Related]

  • 5. Effect of a single amino acid mutation on the activating and immunosuppressive properties of a "humanized" OKT3 monoclonal antibody.
    Alegre ML, Collins AM, Pulito VL, Brosius RA, Olson WC, Zivin RA, Knowles R, Thistlethwaite JR, Jolliffe LK, Bluestone JA.
    J Immunol; 1992 Jun 01; 148(11):3461-8. PubMed ID: 1534096
    [Abstract] [Full Text] [Related]

  • 6. Immunosuppressive properties of anti-CD3 single-chain Fv and diabody.
    Le Gall F, Reusch U, Moldenhauer G, Little M, Kipriyanov SM.
    J Immunol Methods; 2004 Feb 01; 285(1):111-27. PubMed ID: 14871540
    [Abstract] [Full Text] [Related]

  • 7. An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.
    Alegre ML, Tso JY, Sattar HA, Smith J, Desalle F, Cole M, Bluestone JA.
    J Immunol; 1995 Aug 01; 155(3):1544-55. PubMed ID: 7636216
    [Abstract] [Full Text] [Related]

  • 8. Construction and characterization of a humanized anti-human CD3 monoclonal antibody 12F6 with effective immunoregulation functions.
    Li B, Wang H, Dai J, Ji J, Qian W, Zhang D, Hou S, Guo Y.
    Immunology; 2005 Dec 01; 116(4):487-98. PubMed ID: 16313362
    [Abstract] [Full Text] [Related]

  • 9. Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells.
    Rodrigues ML, Shalaby MR, Werther W, Presta L, Carter P.
    Int J Cancer Suppl; 1992 Dec 01; 7():45-50. PubMed ID: 1428403
    [Abstract] [Full Text] [Related]

  • 10. Novel humanized anti-CD3 antibodies induce a predominantly immunoregulatory profile in human peripheral blood mononuclear cells.
    Silva HM, Vieira PM, Costa PL, Pimentel BM, Moro AM, Kalil J, Maranhão AQ, Coelho V, Brigido MM.
    Immunol Lett; 2009 Aug 15; 125(2):129-36. PubMed ID: 19573559
    [Abstract] [Full Text] [Related]

  • 11. A non-activating "humanized" anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo.
    Alegre ML, Peterson LJ, Xu D, Sattar HA, Jeyarajah DR, Kowalkowski K, Thistlethwaite JR, Zivin RA, Jolliffe L, Bluestone JA.
    Transplantation; 1994 Jun 15; 57(11):1537-43. PubMed ID: 8009586
    [Abstract] [Full Text] [Related]

  • 12. HuM291, a humanized anti-CD3 antibody, is immunosuppressive to T cells while exhibiting reduced mitogenicity in vitro.
    Cole MS, Stellrecht KE, Shi JD, Homola M, Hsu DH, Anasetti C, Vasquez M, Tso JY.
    Transplantation; 1999 Aug 27; 68(4):563-71. PubMed ID: 10480417
    [Abstract] [Full Text] [Related]

  • 13. Phase I evaluation of humanized OKT3: toxicity and immunomodulatory effects of hOKT3gamma4.
    Richards J, Auger J, Peace D, Gale D, Michel J, Koons A, Haverty T, Zivin R, Jolliffe L, Bluestone JA.
    Cancer Res; 1999 May 01; 59(9):2096-101. PubMed ID: 10232594
    [Abstract] [Full Text] [Related]

  • 14. Modulation of antigen-specific T cell response by a non-mitogenic anti-CD3 antibody.
    Li J, Davis J, Bracht M, Carton J, Armstrong J, Gao W, Scallon B, Fung R, Emmell E, Zimmerman M, Griswold DE, Li L.
    Int Immunopharmacol; 2006 Jun 01; 6(6):880-91. PubMed ID: 16644473
    [Abstract] [Full Text] [Related]

  • 15. Humanization of anti-human insulin receptor antibody for drug targeting across the human blood-brain barrier.
    Boado RJ, Zhang Y, Zhang Y, Pardridge WM.
    Biotechnol Bioeng; 2007 Feb 01; 96(2):381-91. PubMed ID: 16937408
    [Abstract] [Full Text] [Related]

  • 16. Humanization and pharmacokinetics of a monoclonal antibody with specificity for both E- and P-selectin.
    He XY, Xu Z, Melrose J, Mullowney A, Vasquez M, Queen C, Vexler V, Klingbeil C, Co MS, Berg EL.
    J Immunol; 1998 Jan 15; 160(2):1029-35. PubMed ID: 9551944
    [Abstract] [Full Text] [Related]

  • 17. Humanization and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A.
    Pulito VL, Roberts VA, Adair JR, Rothermel AL, Collins AM, Varga SS, Martocello C, Bodmer M, Jolliffe LK, Zivin RA.
    J Immunol; 1996 Apr 15; 156(8):2840-50. PubMed ID: 8609403
    [Abstract] [Full Text] [Related]

  • 18. A humanized monovalent CD3 antibody which can activate homologous complement.
    Routledge EG, Lloyd I, Gorman SD, Clark M, Waldmann H.
    Eur J Immunol; 1991 Nov 15; 21(11):2717-25. PubMed ID: 1834468
    [Abstract] [Full Text] [Related]

  • 19. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H, Nie Y, Huse WD, Watkins JD.
    J Mol Biol; 1999 Nov 19; 294(1):151-62. PubMed ID: 10556035
    [Abstract] [Full Text] [Related]

  • 20. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1.
    Werther WA, Gonzalez TN, O'Connor SJ, McCabe S, Chan B, Hotaling T, Champe M, Fox JA, Jardieu PM, Berman PW, Presta LG.
    J Immunol; 1996 Dec 01; 157(11):4986-95. PubMed ID: 8943405
    [Abstract] [Full Text] [Related]

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