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146 related items for PubMed ID: 7864895
1. Changing the inhibitory specificity and function of Cucurbita maxima trypsin inhibitor-V by site-directed mutagenesis. Wen L, Lee I, Chen G, Huang JK, Gong Y, Krishnamoorthi R. Biochem Biophys Res Commun; 1995 Feb 27; 207(3):897-902. PubMed ID: 7864895 [Abstract] [Full Text] [Related]
2. Chemical synthesis, molecular cloning, overexpression, and site-directed mutagenesis of the gene coding for pumpkin (Curcubita maxima) trypsin inhibitor CMTI-V. Wen L, Kim SS, Tinn TT, Huang JK, Krishnamoorthi R, Gong YX, Lwin YN, Kyin S. Protein Expr Purif; 1993 Jun 27; 4(3):215-22. PubMed ID: 8518561 [Abstract] [Full Text] [Related]
3. Reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor-V: function, thermodynamic stability, and NMR solution structure. Cai M, Gong Y, Prakash O, Krishnamoorthi R. Biochemistry; 1995 Sep 26; 34(38):12087-94. PubMed ID: 7547948 [Abstract] [Full Text] [Related]
4. NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor (CMTI)-III of the squash family and comparison with those of counterparts of CMTI-V of the potato I family. Liu J, Gong Y, Prakash O, Wen L, Lee I, Huang JK, Krishnamoorthi R. Protein Sci; 1998 Jan 26; 7(1):132-41. PubMed ID: 9514268 [Abstract] [Full Text] [Related]
5. Distance between the basic group of the amino acid residue's side chain in position P1 of trypsin inhibitor CMTI-III and Asp189 in the substrate pocket of trypsin has an essential influence on the inhibitory activity. Jaśkiewicz A, Lesner A, Rózycki J, Rodziewicz S, Rolka K, Ragnarsson U, Kupryszewski G. Biochem Biophys Res Commun; 1997 Nov 26; 240(3):869-71. PubMed ID: 9398660 [Abstract] [Full Text] [Related]
6. Replacement of lysine by arginine, phenylalanine and tryptophan in the reactive site of the bovine trypsin-kallikrein inhibitor (Kunitz) and change of the inhibitory properties. Jering H, Tschesche H. Eur J Biochem; 1976 Jan 15; 61(2):453-63. PubMed ID: 129327 [Abstract] [Full Text] [Related]
7. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Scheidig AJ, Hynes TR, Pelletier LA, Wells JA, Kossiakoff AA. Protein Sci; 1997 Sep 15; 6(9):1806-24. PubMed ID: 9300481 [Abstract] [Full Text] [Related]
8. Single peptide bond hydrolysis/resynthesis in squash inhibitors of serine proteinases. 1. Kinetics and thermodynamics of the interaction between squash inhibitors and bovine beta-trypsin. Otlewski J, Zbyryt T. Biochemistry; 1994 Jan 11; 33(1):200-7. PubMed ID: 8286341 [Abstract] [Full Text] [Related]
9. High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes. Helland R, Berglund GI, Otlewski J, Apostoluk W, Andersen OA, Willassen NP, Smalås AO. Acta Crystallogr D Biol Crystallogr; 1999 Jan 11; 55(Pt 1):139-48. PubMed ID: 10089404 [Abstract] [Full Text] [Related]
10. Internal mobility of reactive-site-hydrolyzed recombinant Cucurbita maxima trypsin inhibitor-V characterized by NMR spectroscopy: evidence for differential stabilization of newly formed C- and N-termini. Liu J, Prakash O, Huang Y, Wen L, Wen JJ, Huang JK, Krishnamoorthi R. Biochemistry; 1996 Sep 24; 35(38):12503-10. PubMed ID: 8823186 [Abstract] [Full Text] [Related]
11. Synthesis of a squash-type protease inhibitor by gene engineering and effects of replacements of conserved hydrophobic amino acid residues on its inhibitory activity. Kojima S, Miyoshi K, Miura K. Protein Eng; 1996 Dec 24; 9(12):1241-6. PubMed ID: 9010939 [Abstract] [Full Text] [Related]
12. Two-dimensional NMR studies of squash family inhibitors. Sequence-specific proton assignments and secondary structure of reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor III. Krishnamoorthi R, Gong YX, Lin CL, VanderVelde D. Biochemistry; 1992 Jan 28; 31(3):898-904. PubMed ID: 1731946 [Abstract] [Full Text] [Related]
13. Differential modulation of binding loop flexibility and stability by Arg50 and Arg52 in Cucurbita maxima trypsin inhibitor-V deduced by trypsin-catalyzed hydrolysis and NMR spectroscopy. Cai M, Huang Y, Prakash O, Wen L, Dunkelbarger SP, Huang JK, Liu J, Krishnamoorthi R. Biochemistry; 1996 Apr 16; 35(15):4784-94. PubMed ID: 8664268 [Abstract] [Full Text] [Related]
14. Design, chemical synthesis and kinetic studies of trypsin chromogenic substrates based on the proteinase binding loop of Cucurbita maxima trypsin inhibitor (CMTI-III). Lesner A, Brzozowski K, Kupryszewski G, Rolka K. Biochem Biophys Res Commun; 2000 Mar 05; 269(1):81-4. PubMed ID: 10694481 [Abstract] [Full Text] [Related]
15. Correlation of binding-loop internal dynamics with stability and function in potato I inhibitor family: relative contributions of Arg(50) and Arg(52) in Cucurbita maxima trypsin inhibitor-V as studied by site-directed mutagenesis and NMR spectroscopy. Cai M, Gong YX, Wen L, Krishnamoorthi R. Biochemistry; 2002 Jul 30; 41(30):9572-9. PubMed ID: 12135379 [Abstract] [Full Text] [Related]
16. Selection of low-molecular-mass trypsin and chymotrypsin inhibitors based on the binding loop of CMTI-III using combinatorial chemistry methods. Kaźmierczak K, Zabłotna E, Jaśkiewicz A, Miecznikowska H, Rolka K. Biochem Biophys Res Commun; 2003 Oct 24; 310(3):811-5. PubMed ID: 14550276 [Abstract] [Full Text] [Related]
17. Synthesis, cloning and expression in Escherichia coli of a gene coding for the Met8-->Leu CMTI I--a representative of the squash inhibitors of serine proteinases. Bolewska K, Krowarsch D, Otlewski J, Jaroszewski L, Bierzynski A. FEBS Lett; 1995 Dec 18; 377(2):172-4. PubMed ID: 8543044 [Abstract] [Full Text] [Related]
18. New active analogues of Cucurbita maxima trypsin inhibitor III (CMTI-III) modified in the non-contact region. Rózycki J, Kupryszewski G, Rolka K, Ragnarsson U, Zbyryt T, Krokoszyńska I, Wilusz T. Biol Chem Hoppe Seyler; 1994 Jan 18; 375(1):21-3. PubMed ID: 8003251 [Abstract] [Full Text] [Related]
19. New analogues of Cucurbita maxima trypsin inhibitor III (CMTI III) with simplified structure. Rolka K, Kupryszewski G, Rózycki J, Ragnarsson U, Zbyryt T, Otlewski J. Biol Chem Hoppe Seyler; 1992 Oct 18; 373(10):1055-60. PubMed ID: 1418676 [Abstract] [Full Text] [Related]
20. Reaction of lentil trypsin-chymotrypsin inhibitors with human and bovine proteinases. Weder JK, Kahleyss R. J Agric Food Chem; 2003 Dec 31; 51(27):8045-50. PubMed ID: 14690394 [Abstract] [Full Text] [Related] Page: [Next] [New Search]