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Journal Abstract Search

172 related items for PubMed ID: 7870050

  • 1. Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae.
    Rogers MJ, Xiong X, Brown RJ, Watts DJ, Russell RG, Bayless AV, Ebetino FH.
    Mol Pharmacol; 1995 Feb; 47(2):398-402. PubMed ID: 7870050
    [Abstract] [Full Text] [Related]

  • 2. Inhibitory effects of bisphosphonates on growth of amoebae of the cellular slime mold Dictyostelium discoideum.
    Rogers MJ, Watts DJ, Russell RG, Ji X, Xiong X, Blackburn GM, Bayless AV, Ebetino FH.
    J Bone Miner Res; 1994 Jul; 9(7):1029-39. PubMed ID: 7942149
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates.
    Dunford JE, Thompson K, Coxon FP, Luckman SP, Hahn FM, Poulter CD, Ebetino FH, Rogers MJ.
    J Pharmacol Exp Ther; 2001 Feb; 296(2):235-42. PubMed ID: 11160603
    [Abstract] [Full Text] [Related]

  • 4. Differential effects of aminosubstituted analogs of hydroxy bisphosphonates on the growth of Dictyostelium discoideum.
    Brown RJ, van Beek E, Watts DJ, Löwik CW, Papapoulos SE.
    J Bone Miner Res; 1998 Feb; 13(2):253-8. PubMed ID: 9495518
    [Abstract] [Full Text] [Related]

  • 5. Bisphosphonates: structure-activity relations from a clinical perspective.
    Papapoulos SE.
    Medicina (B Aires); 1997 Feb; 57 Suppl 1():61-4. PubMed ID: 9567357
    [Abstract] [Full Text] [Related]

  • 6. The relationship between the chemistry and biological activity of the bisphosphonates.
    Ebetino FH, Hogan AM, Sun S, Tsoumpra MK, Duan X, Triffitt JT, Kwaasi AA, Dunford JE, Barnett BL, Oppermann U, Lundy MW, Boyde A, Kashemirov BA, McKenna CE, Russell RG.
    Bone; 2011 Jul; 49(1):20-33. PubMed ID: 21497677
    [Abstract] [Full Text] [Related]

  • 7. Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum.
    Rogers MJ, Ji X, Russell RG, Blackburn GM, Williamson MP, Bayless AV, Ebetino FH, Watts DJ.
    Biochem J; 1994 Oct 01; 303 ( Pt 1)(Pt 1):303-11. PubMed ID: 7945256
    [Abstract] [Full Text] [Related]

  • 8. Molecular mechanisms of action of bisphosphonates: current status.
    Roelofs AJ, Thompson K, Gordon S, Rogers MJ.
    Clin Cancer Res; 2006 Oct 15; 12(20 Pt 2):6222s-6230s. PubMed ID: 17062705
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of growth of Dictyostelium discoideum amoebae by bisphosphonate drugs is dependent on cellular uptake.
    Rogers MJ, Xiong X, Ji X, Mönkkönen J, Russell RG, Williamson MP, Ebetino FH, Watts DJ.
    Pharm Res; 1997 May 15; 14(5):625-30. PubMed ID: 9165534
    [Abstract] [Full Text] [Related]

  • 10. A quantitative structure-activity relationship and pharmacophore modeling investigation of aryl-X and heterocyclic bisphosphonates as bone resorption agents.
    Kotsikorou E, Oldfield E.
    J Med Chem; 2003 Jul 03; 46(14):2932-44. PubMed ID: 12825934
    [Abstract] [Full Text] [Related]

  • 11. From molds and macrophages to mevalonate: a decade of progress in understanding the molecular mode of action of bisphosphonates.
    Rogers MJ.
    Calcif Tissue Int; 2004 Dec 03; 75(6):451-61. PubMed ID: 15332174
    [Abstract] [Full Text] [Related]

  • 12. Antiresorptive dose-response relationships across three generations of bisphosphonates.
    Sietsema WK, Ebetino FH, Salvagno AM, Bevan JA.
    Drugs Exp Clin Res; 1989 Dec 03; 15(9):389-96. PubMed ID: 2630251
    [Abstract] [Full Text] [Related]

  • 13. Differential effects of Ca(2+) on bisphosphonate-induced growth inhibition in breast cancer and mesothelioma cells.
    Merrell MA, Wakchoure S, Ilvesaro JM, Zinn K, Gehrs B, Lehenkari PP, Harris KW, Selander KS.
    Eur J Pharmacol; 2007 Mar 15; 559(1):21-31. PubMed ID: 17214981
    [Abstract] [Full Text] [Related]

  • 14. Structural requirements for bisphosphonate actions in vitro.
    van Beek E, Hoekstra M, van de Ruit M, Löwik C, Papapoulos S.
    J Bone Miner Res; 1994 Dec 15; 9(12):1875-82. PubMed ID: 7872052
    [Abstract] [Full Text] [Related]

  • 15. Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
    Sanders JM, Song Y, Chan JM, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Gómez AO, González-Pacanowska D, Raker AM, Wang H, van Beek ER, Papapoulos SE, Morita CT, Oldfield E.
    J Med Chem; 2005 Apr 21; 48(8):2957-63. PubMed ID: 15828834
    [Abstract] [Full Text] [Related]

  • 16. An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.
    Szabo CM, Martin MB, Oldfield E.
    J Med Chem; 2002 Jul 04; 45(14):2894-903. PubMed ID: 12086477
    [Abstract] [Full Text] [Related]

  • 17. Bisphosphonate inhibitors of Toxoplasma gondi growth: in vitro, QSAR, and in vivo investigations.
    Ling Y, Sahota G, Odeh S, Chan JM, Araujo FG, Moreno SN, Oldfield E.
    J Med Chem; 2005 May 05; 48(9):3130-40. PubMed ID: 15857119
    [Abstract] [Full Text] [Related]

  • 18. The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase.
    Grove JE, Brown RJ, Watts DJ.
    J Bone Miner Res; 2000 May 05; 15(5):971-81. PubMed ID: 10804029
    [Abstract] [Full Text] [Related]

  • 19. Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes.
    Rogers MJ, Brown RJ, Hodkin V, Blackburn GM, Russell RG, Watts DJ.
    Biochem Biophys Res Commun; 1996 Jul 25; 224(3):863-9. PubMed ID: 8713136
    [Abstract] [Full Text] [Related]

  • 20. Antitumor effects of bisphosphonates.
    Green JR.
    Cancer; 2003 Feb 01; 97(3 Suppl):840-7. PubMed ID: 12548584
    [Abstract] [Full Text] [Related]

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