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208 related items for PubMed ID: 7890748
1. A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons. Knab AM, Fertala J, Bjornsti MA. J Biol Chem; 1995 Mar 17; 270(11):6141-8. PubMed ID: 7890748 [Abstract] [Full Text] [Related]
2. Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants. Knab AM, Fertala J, Bjornsti MA. J Biol Chem; 1993 Oct 25; 268(30):22322-30. PubMed ID: 8226741 [Abstract] [Full Text] [Related]
3. Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I. Morham SG, Shuman S. J Biol Chem; 1992 Aug 05; 267(22):15984-92. PubMed ID: 1322412 [Abstract] [Full Text] [Related]
4. An engineered mutant of vaccinia virus DNA topoisomerase I is sensitive to the anti-cancer drug camptothecin. Gupta M, Zhu CX, Tse-Dinh YC. J Biol Chem; 1992 Dec 05; 267(34):24177-80. PubMed ID: 1332948 [Abstract] [Full Text] [Related]
5. Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine. Benedetti P, Fiorani P, Capuani L, Wang JC. Cancer Res; 1993 Sep 15; 53(18):4343-8. PubMed ID: 8395982 [Abstract] [Full Text] [Related]
7. Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity. Fiorani P, Amatruda JF, Silvestri A, Butler RH, Bjornsti MA, Benedetti P. Mol Pharmacol; 1999 Dec 15; 56(6):1105-15. PubMed ID: 10570037 [Abstract] [Full Text] [Related]
8. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Eng WK, Faucette L, Johnson RK, Sternglanz R. Mol Pharmacol; 1988 Dec 15; 34(6):755-60. PubMed ID: 2849043 [Abstract] [Full Text] [Related]
12. Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I. Gromova II, Kjeldsen E, Svejstrup JQ, Alsner J, Christiansen K, Westergaard O. Nucleic Acids Res; 1993 Feb 11; 21(3):593-600. PubMed ID: 8382801 [Abstract] [Full Text] [Related]
13. Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line. Urasaki Y, Laco GS, Pourquier P, Takebayashi Y, Kohlhagen G, Gioffre C, Zhang H, Chatterjee D, Pantazis P, Pommier Y. Cancer Res; 2001 Mar 01; 61(5):1964-9. PubMed ID: 11280753 [Abstract] [Full Text] [Related]
14. DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin. Wright CM, van der Merwe M, DeBrot AH, Bjornsti MA. J Biol Chem; 2015 May 08; 290(19):12068-78. PubMed ID: 25795777 [Abstract] [Full Text] [Related]
15. Yeast Saccharomyces cerevisiae as a model system to study the cytotoxic activity of the antitumor drug camptothecin. Bjornsti MA, Knab AM, Benedetti P. Cancer Chemother Pharmacol; 1994 May 08; 34 Suppl():S1-5. PubMed ID: 8070016 [Abstract] [Full Text] [Related]
16. Overexpression of human topoisomerase I in baby hamster kidney cells: hypersensitivity of clonal isolates to camptothecin. Madden KR, Champoux JJ. Cancer Res; 1992 Feb 01; 52(3):525-32. PubMed ID: 1310066 [Abstract] [Full Text] [Related]
17. Cloning of Chinese hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance. Tanizawa A, Beitrand R, Kohlhagen G, Tabuchi A, Jenkins J, Pommier Y. J Biol Chem; 1993 Dec 05; 268(34):25463-8. PubMed ID: 8244980 [Abstract] [Full Text] [Related]
18. Directed evolution to increase camptothecin sensitivity of human DNA topoisomerase I. Scaldaferro S, Tinelli S, Borgnetto ME, Azzini A, Capranico G. Chem Biol; 2001 Sep 05; 8(9):871-81. PubMed ID: 11564555 [Abstract] [Full Text] [Related]
19. The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives. A model for topoisomerase I inhibition by indolocarbazoles. Bailly C, Carrasco C, Hamy F, Vezin H, Prudhomme M, Saleem A, Rubin E. Biochemistry; 1999 Jul 06; 38(27):8605-11. PubMed ID: 10393535 [Abstract] [Full Text] [Related]