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2. Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Seldon PM, Barnes PJ, Meja K, Giembycz MA. Mol Pharmacol; 1995 Oct; 48(4):747-57. PubMed ID: 7476903 [Abstract] [Full Text] [Related]
3. Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes. Seldon PM, Barnes PJ, Giembycz MA. Cell Biochem Biophys; 1998 Oct; 29(1-2):179-201. PubMed ID: 9631245 [Abstract] [Full Text] [Related]
4. Cyclic nucleotide phosphodiesterase type IV participates in the regulation of IL-10 and in the subsequent inhibition of TNF-alpha and IL-6 release by endotoxin-stimulated macrophages. Kambayashi T, Jacob CO, Zhou D, Mazurek N, Fong M, Strassmann G. J Immunol; 1995 Nov 15; 155(10):4909-16. PubMed ID: 7594495 [Abstract] [Full Text] [Related]
5. In vitro differentiation of human monocytes to macrophages: change of PDE profile and its relationship to suppression of tumour necrosis factor-alpha release by PDE inhibitors. Gantner F, Kupferschmidt R, Schudt C, Wendel A, Hatzelmann A. Br J Pharmacol; 1997 May 15; 121(2):221-31. PubMed ID: 9154331 [Abstract] [Full Text] [Related]
6. The ability of phosphodiesterase IV inhibitors to suppress superoxide production in guinea pig eosinophils is correlated with inhibition of phosphodiesterase IV catalytic activity. Barnette MS, Manning CD, Cieslinski LB, Burman M, Christensen SB, Torphy TJ. J Pharmacol Exp Ther; 1995 May 15; 273(2):674-9. PubMed ID: 7752069 [Abstract] [Full Text] [Related]
7. Modulation of antigen- and mitogen-induced proliferative responses of peripheral blood mononuclear cells by nonselective and isozyme selective cyclic nucleotide phosphodiesterase inhibitors. Essayan DM, Huang SK, Undem BJ, Kagey-Sobotka A, Lichtenstein LM. J Immunol; 1994 Oct 15; 153(8):3408-16. PubMed ID: 7930566 [Abstract] [Full Text] [Related]
8. Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site. Barnette MS, Grous M, Cieslinski LB, Burman M, Christensen SB, Torphy TJ. J Pharmacol Exp Ther; 1995 Jun 15; 273(3):1396-402. PubMed ID: 7791113 [Abstract] [Full Text] [Related]
9. Identification, characterization, and functional role of phosphodiesterase type IV in cerebral vessels: effects of selective phosphodiesterase inhibitors. Willette RN, Shiloh AO, Sauermelch CF, Sulpizio A, Michell MP, Cieslinski LB, Torphy TJ, Ohlstein EH. J Cereb Blood Flow Metab; 1997 Feb 15; 17(2):210-9. PubMed ID: 9040501 [Abstract] [Full Text] [Related]
10. Differential modulation of cytokine production by drugs: implications for therapy in heart failure. Matsumori A, Ono K, Sato Y, Shioi T, Nose Y, Sasayama S. J Mol Cell Cardiol; 1996 Dec 15; 28(12):2491-9. PubMed ID: 9004165 [Abstract] [Full Text] [Related]
11. In vitro down-regulation of antigen-induced IL-5 gene expression and protein production by cAMP-specific phosphodiesterase type 4 inhibitor. Foissier L, Lonchampt M, Cogé F, Canet E. J Pharmacol Exp Ther; 1996 Sep 15; 278(3):1484-90. PubMed ID: 8819536 [Abstract] [Full Text] [Related]
12. Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity. Torphy TJ, Zhou HL, Cieslinski LB. J Pharmacol Exp Ther; 1992 Dec 15; 263(3):1195-205. PubMed ID: 1335058 [Abstract] [Full Text] [Related]
13. Potentiation of erectile response and cAMP accumulation by combination of prostaglandin E1 and rolipram, a selective inhibitor of the type 4 phosphodiesterase (PDE 4). Bivalacqua TJ, Champion HC, Rajasekaran M, Sikka SC, Kadowitz PJ, Doherty PC, Hellstrom WJ. J Urol; 1999 Nov 15; 162(5):1848-55. PubMed ID: 10524946 [Abstract] [Full Text] [Related]
14. Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S. Eur J Immunol; 1995 Jan 15; 25(1):147-53. PubMed ID: 7843225 [Abstract] [Full Text] [Related]
18. Preliminary identification and role of phosphodiesterase isozymes in human basophils. Peachell PT, Undem BJ, Schleimer RP, MacGlashan DW, Lichtenstein LM, Cieslinski LB, Torphy TJ. J Immunol; 1992 Apr 15; 148(8):2503-10. PubMed ID: 1373172 [Abstract] [Full Text] [Related]
19. Characterization of indolidan- and rolipram-sensitive cyclic nucleotide phosphodiesterases in canine and human cardiac microsomal fractions. Lugnier C, Muller B, Le Bec A, Beaudry C, Rousseau E. J Pharmacol Exp Ther; 1993 Jun 15; 265(3):1142-51. PubMed ID: 8389853 [Abstract] [Full Text] [Related]
20. Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol. Dent G, Giembycz MA, Evans PM, Rabe KF, Barnes PJ. J Pharmacol Exp Ther; 1994 Dec 15; 271(3):1167-74. PubMed ID: 7996422 [Abstract] [Full Text] [Related] Page: [Next] [New Search]