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Journal Abstract Search

167 related items for PubMed ID: 7891353

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  • 3. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.
    Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA.
    Chem Res Toxicol; 1999 Feb; 12(2):192-9. PubMed ID: 10027798
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  • 5. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 6. The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man.
    Maggs JL, Williams D, Pirmohamed M, Park BK.
    J Pharmacol Exp Ther; 1995 Dec; 275(3):1463-75. PubMed ID: 8531117
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  • 8. Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro.
    Williams DP, O'Donnell CJ, Maggs JL, Leeder JS, Uetrecht J, Pirmohamed M, Park BK.
    Chem Res Toxicol; 2003 Oct; 16(10):1359-64. PubMed ID: 14565776
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  • 10. Neutrophil cytotoxicity of the chemically reactive metabolite(s) of clozapine: possible role in agranulocytosis.
    Williams DP, Pirmohamed M, Naisbitt DJ, Maggs JL, Park BK.
    J Pharmacol Exp Ther; 1997 Dec; 283(3):1375-82. PubMed ID: 9400013
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  • 14. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.
    Wen B, Ma L, Zhu M.
    Chem Biol Interact; 2008 May 09; 173(1):59-67. PubMed ID: 18359012
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  • 15. Metabolism of the cytochrome P450 mechanism-based inhibitor N-benzyl-1-aminobenzotriazole to products that covalently bind with protein in guinea pig liver and lung microsomes: comparative study with 1-aminobenzotriazole.
    Woodcroft KJ, Webb CD, Yao M, Weedon AC, Bend JR.
    Chem Res Toxicol; 1997 May 09; 10(5):589-99. PubMed ID: 9168258
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  • 16. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Masubuchi Y, Igarashi S, Suzuki T, Horie T, Narimatsu S.
    J Pharmacol Exp Ther; 1996 Nov 09; 279(2):724-31. PubMed ID: 8930177
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  • 19. Protein-reactive metabolites of carbamazepine in mouse liver microsomes.
    Lillibridge JH, Amore BM, Slattery JT, Kalhorn TF, Nelson SD, Finnell RH, Bennett GD.
    Drug Metab Dispos; 1996 May 09; 24(5):509-14. PubMed ID: 8723729
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