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112 related items for PubMed ID: 7893672

  • 21. In vitro and in vivo characterization of a neutral boron-containing thrombin inhibitor.
    Tapparelli C, Metternich R, Ehrhardt C, Zurini M, Claeson G, Scully MF, Stone SR.
    J Biol Chem; 1993 Mar 05; 268(7):4734-41. PubMed ID: 8444849
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  • 22. Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models.
    Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD.
    Biochemistry; 1996 Mar 12; 35(10):3147-55. PubMed ID: 8605148
    [Abstract] [Full Text] [Related]

  • 23. Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes.
    Stoll VS, Eger BT, Hynes RC, Martichonok V, Jones JB, Pai EF.
    Biochemistry; 1998 Jan 13; 37(2):451-62. PubMed ID: 9425066
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  • 25. Selective boron-containing thrombin inhibitors--X-ray analysis reveals surprising binding mode.
    von Matt A, Ehrhardt C, Burkhard P, Metternich R, Walkinshaw M, Tapparelli C.
    Bioorg Med Chem; 2000 Sep 13; 8(9):2291-303. PubMed ID: 11026541
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  • 26. The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor.
    Chirgadze NY, Sall DJ, Klimkowski VJ, Clawson DK, Briggs SL, Hermann R, Smith GF, Gifford-Moore DS, Wery JP.
    Protein Sci; 1997 Jul 13; 6(7):1412-7. PubMed ID: 9232642
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  • 27. Molecular basis for the inhibition of human alpha-thrombin by the macrocyclic peptide cyclotheonamide A.
    Maryanoff BE, Qiu X, Padmanabhan KP, Tulinsky A, Almond HR, Andrade-Gordon P, Greco MN, Kauffman JA, Nicolaou KC, Liu A.
    Proc Natl Acad Sci U S A; 1993 Sep 01; 90(17):8048-52. PubMed ID: 8367461
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  • 28. Exploring the chiral space within the active site of alpha-thrombin with a constrained mimic of D-Phe-Pro-Arg--design, synthesis, inhibitory activity, and X-ray structure of an enzyme-inhibitor complex.
    Hanessian S, Balaux E, Musil D, Olsson LL, Nilsson I.
    Bioorg Med Chem Lett; 2000 Feb 07; 10(3):243-7. PubMed ID: 10698445
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  • 29. Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin-binding protein.
    Zervosen A, Herman R, Kerff F, Herman A, Bouillez A, Prati F, Pratt RF, Frère JM, Joris B, Luxen A, Charlier P, Sauvage E.
    J Am Chem Soc; 2011 Jul 20; 133(28):10839-48. PubMed ID: 21574608
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  • 32. Interactions of hirudin-based inhibitor with thrombin: critical role of the IleH59 side chain of the inhibitor.
    Tsuda Y, Szewczuk Z, Wang J, Yue SY, Purisima E, Konishi Y.
    Biochemistry; 1995 Jul 11; 34(27):8708-14. PubMed ID: 7612610
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  • 33. Crystal structure of a peptidyl pyridinium methyl ketone inhibitor with thrombin.
    Rehse PH, Steinmetzer T, Li Y, Konishi Y, Cygler M.
    Biochemistry; 1995 Sep 12; 34(36):11537-44. PubMed ID: 7547884
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  • 34. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
    Malikayil JA, Burkhart JP, Schreuder HA, Broersma RJ, Tardif C, Kutcher LW, Mehdi S, Schatzman GL, Neises B, Peet NP.
    Biochemistry; 1997 Feb 04; 36(5):1034-40. PubMed ID: 9033393
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  • 35. Crystallographic analysis of transition-state mimics bound to penicillopepsin: phosphorus-containing peptide analogues.
    Fraser ME, Strynadka NC, Bartlett PA, Hanson JE, James MN.
    Biochemistry; 1992 Jun 09; 31(22):5201-14. PubMed ID: 1606144
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  • 36. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.
    Zdanov A, Wu S, DiMaio J, Konishi Y, Li Y, Wu X, Edwards BF, Martin PD, Cygler M.
    Proteins; 1993 Nov 09; 17(3):252-65. PubMed ID: 8272424
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  • 37. New peptide boronic acid inhibitors of thrombin.
    Elgendy S, Deadman J, Claeson G.
    Adv Exp Med Biol; 1993 Nov 09; 340():173-8. PubMed ID: 8154333
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  • 38. Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
    Féthière J, Tsuda Y, Coulombe R, Konishi Y, Cygler M.
    Protein Sci; 1996 Jun 09; 5(6):1174-83. PubMed ID: 8762149
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  • 39. Kinetic properties of the binding of alpha-lytic protease to peptide boronic acids.
    Kettner CA, Bone R, Agard DA, Bachovchin WW.
    Biochemistry; 1988 Oct 04; 27(20):7682-8. PubMed ID: 3207699
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  • 40. Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.
    Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M.
    Biochemistry; 1992 Jul 28; 31(29):6646-59. PubMed ID: 1637805
    [Abstract] [Full Text] [Related]

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