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Journal Abstract Search

170 related items for PubMed ID: 7896234

  • 21. Short-term maintenance of phase I and II metabolism in precision-cut liver slices in dynamic organ culture.
    Ekins S.
    Drug Metab Dispos; 1996 Mar; 24(3):364-6. PubMed ID: 8820429
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  • 22. Empirical validation of a rat in vitro organ slice model as a tool for in vivo clearance prediction.
    de Graaf IA, de Kanter R, de Jager MH, Camacho R, Langenkamp E, van de Kerkhof EG, Groothuis GM.
    Drug Metab Dispos; 2006 Apr; 34(4):591-9. PubMed ID: 16415126
    [Abstract] [Full Text] [Related]

  • 23. The metabolism of 7-ethoxycoumarin in primary maintenance cultures of adult rat hepatocytes.
    Fry JR, Bridges JW.
    Naunyn Schmiedebergs Arch Pharmacol; 1980 Feb; 311(1):85-90. PubMed ID: 7366743
    [Abstract] [Full Text] [Related]

  • 24. Metabolism of [3-14C] coumarin by human liver microsomes.
    van Iersel ML, Henderson CJ, Walters DG, Price RJ, Wolf CR, Lake BG.
    Xenobiotica; 1994 Aug; 24(8):795-803. PubMed ID: 7839702
    [Abstract] [Full Text] [Related]

  • 25. Induction of physical dependence by chronic alcohol treatment and enhancement of hepatic metabolism of 7-ethoxycoumarin and subsequent conjugation of its metabolite in perfused rat livers.
    Hong SS, Roh HK, Dong MS, Cha YN.
    Arch Int Pharmacodyn Ther; 1987 Feb; 285(2):249-62. PubMed ID: 3579427
    [Abstract] [Full Text] [Related]

  • 26. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA, Vezina CM, McGarrigle BP, Ersing N, Box HC, Maccubbin AE, Olson JR.
    Toxicol Sci; 2004 Feb; 77(2):307-14. PubMed ID: 14691214
    [Abstract] [Full Text] [Related]

  • 27. A microfluidic approach for in vitro assessment of interorgan interactions in drug metabolism using intestinal and liver slices.
    van Midwoud PM, Merema MT, Verpoorte E, Groothuis GM.
    Lab Chip; 2010 Oct 21; 10(20):2778-86. PubMed ID: 20835427
    [Abstract] [Full Text] [Related]

  • 28. Functional relationship between initial oxidation of 7-ethoxycoumarin and subsequent conjugation of 7-hydroxycoumarin in isolated perfused rat livers.
    Cha YN, Dong MS, Hong SS.
    Chem Biol Interact; 1987 Feb 21; 61(2):125-37. PubMed ID: 3829139
    [Abstract] [Full Text] [Related]

  • 29. Metabolism of nicotine and induction of CYP1A forms in precision-cut rat liver and lung slices.
    Price RJ, Renwick AB, Walters DG, Young PJ, Lake BG.
    Toxicol In Vitro; 2004 Apr 21; 18(2):179-85. PubMed ID: 14757108
    [Abstract] [Full Text] [Related]

  • 30. Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies.
    van de Kerkhof EG, de Graaf IA, de Jager MH, Meijer DK, Groothuis GM.
    Drug Metab Dispos; 2005 Nov 21; 33(11):1613-20. PubMed ID: 16051733
    [Abstract] [Full Text] [Related]

  • 31. Kinetics of drug metabolism in rat liver slices. Rates of oxidation of ethoxycoumarin and tolbutamide, examples of high- and low-clearance compounds.
    Worboys PD, Bradbury A, Houston JB.
    Drug Metab Dispos; 1995 Mar 21; 23(3):393-7. PubMed ID: 7628306
    [Abstract] [Full Text] [Related]

  • 32. Metabolism of [3-14C]coumarin to polar and covalently bound products by hepatic microsomes from the rat, Syrian hamster, gerbil and humans.
    Lake BG, Gaudin H, Price RJ, Walters DG.
    Food Chem Toxicol; 1992 Feb 21; 30(2):105-15. PubMed ID: 1555792
    [Abstract] [Full Text] [Related]

  • 33. Metabolism of dichlorobenzenes in organ cultured liver slices.
    Fisher R, McCarthy S, Sipes IG, Hanzlik RP, Brendel K.
    Adv Exp Med Biol; 1991 Feb 21; 283():717-23. PubMed ID: 2069046
    [Abstract] [Full Text] [Related]

  • 34. Metabolism of coumarin by rat, gerbil and human liver microsomes.
    Fentem JH, Fry JR.
    Xenobiotica; 1992 Mar 21; 22(3):357-67. PubMed ID: 1496825
    [Abstract] [Full Text] [Related]

  • 35. Cytochrome P450-dependent metabolic pathways and glucuronidation in trout liver slices.
    Cravedi JP, Perdu-Durand E, Paris A.
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol; 1998 Nov 21; 121(1-3):267-75. PubMed ID: 9972468
    [Abstract] [Full Text] [Related]

  • 36. Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
    Carlile DJ, Hakooz N, Houston JB.
    Drug Metab Dispos; 1999 Apr 21; 27(4):526-32. PubMed ID: 10101148
    [Abstract] [Full Text] [Related]

  • 37. In Vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices.
    Nave R, Fisher R, Zech K.
    Biopharm Drug Dispos; 2006 May 21; 27(4):197-207. PubMed ID: 16566061
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  • 38. Quantitative differences in phase I and II metabolism between rat precision-cut liver slices and isolated hepatocytes.
    Ekins S, Murray GI, Burke MD, Williams JA, Marchant NC, Hawksworth GM.
    Drug Metab Dispos; 1995 Nov 21; 23(11):1274-9. PubMed ID: 8591730
    [Abstract] [Full Text] [Related]

  • 39. Determination of 7-hydroxycoumarin and its glucuronide and sulphate conjugates in liver slice incubates by capillary zone electrophoresis.
    Duffy CF, O'Kennedy R.
    J Pharm Biomed Anal; 1998 Sep 21; 17(8):1279-84. PubMed ID: 9800648
    [Abstract] [Full Text] [Related]

  • 40. Predictive value of liver slices for metabolism and toxicity in vivo: use of acetaminophen as a model hepatotoxicant.
    Miller MG, Beyer J, Hall GL, deGraffenried LA, Adams PE.
    Toxicol Appl Pharmacol; 1993 Sep 21; 122(1):108-16. PubMed ID: 8378925
    [Abstract] [Full Text] [Related]

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