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Journal Abstract Search

208 related items for PubMed ID: 7908437

  • 1. X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
    Eigenbrot C, Gonzalez T, Mayeda J, Carter P, Werther W, Hotaling T, Fox J, Kessler J.
    Proteins; 1994 Jan; 18(1):49-62. PubMed ID: 7908437
    [Abstract] [Full Text] [Related]

  • 2. X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling.
    Eigenbrot C, Randal M, Presta L, Carter P, Kossiakoff AA.
    J Mol Biol; 1993 Feb 20; 229(4):969-95. PubMed ID: 8095303
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC, Shan L, Goldsteen BZ, Guddat LW, Thakur A, Landolfi NF, Co MS, Vasquez M, Queen C, Ramsland PA, Edmundson AB.
    J Mol Recognit; 1999 Feb 20; 12(1):19-32. PubMed ID: 10398393
    [Abstract] [Full Text] [Related]

  • 4. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
    Chen Y, Wiesmann C, Fuh G, Li B, Christinger HW, McKay P, de Vos AM, Lowman HB.
    J Mol Biol; 1999 Nov 05; 293(4):865-81. PubMed ID: 10543973
    [Abstract] [Full Text] [Related]

  • 5. Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms.
    Bourne PC, Terzyan SS, Cloud G, Landolfi NF, Vásquez M, Edmundson AB.
    Acta Crystallogr D Biol Crystallogr; 2004 Oct 05; 60(Pt 10):1761-9. PubMed ID: 15388922
    [Abstract] [Full Text] [Related]

  • 6. The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.
    Nakasako M, Takahashi H, Shimba N, Shimada I, Arata Y.
    J Mol Biol; 1999 Aug 06; 291(1):117-34. PubMed ID: 10438610
    [Abstract] [Full Text] [Related]

  • 7. Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
    Mylvaganam SE, Paterson Y, Getzoff ED.
    J Mol Biol; 1998 Aug 14; 281(2):301-22. PubMed ID: 9698550
    [Abstract] [Full Text] [Related]

  • 8. Refined structure of an intact IgG2a monoclonal antibody.
    Harris LJ, Larson SB, Hasel KW, McPherson A.
    Biochemistry; 1997 Feb 18; 36(7):1581-97. PubMed ID: 9048542
    [Abstract] [Full Text] [Related]

  • 9. Crystal structure of the disulfide-stabilized Fv fragment of anticancer antibody B1: conformational influence of an engineered disulfide bond.
    Almog O, Benhar I, Vasmatzis G, Tordova M, Lee B, Pastan I, Gilliland GL.
    Proteins; 1998 May 01; 31(2):128-38. PubMed ID: 9593187
    [Abstract] [Full Text] [Related]

  • 10. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
    Wu H, Nie Y, Huse WD, Watkins JD.
    J Mol Biol; 1999 Nov 19; 294(1):151-62. PubMed ID: 10556035
    [Abstract] [Full Text] [Related]

  • 11. Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex.
    Sogabe S, Stuart F, Henke C, Bridges A, Williams G, Birch A, Winkler FK, Robinson JA.
    J Mol Biol; 1997 Nov 07; 273(4):882-97. PubMed ID: 9367779
    [Abstract] [Full Text] [Related]

  • 12. Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.
    Cheetham GM, Hale G, Waldmann H, Bloomer AC.
    J Mol Biol; 1998 Nov 20; 284(1):85-99. PubMed ID: 9811544
    [Abstract] [Full Text] [Related]

  • 13. Optimal humanization of 1B4, an anti-CD18 murine monoclonal antibody, is achieved by correct choice of human V-region framework sequences.
    Singer II, Kawka DW, DeMartino JA, Daugherty BL, Elliston KO, Alves K, Bush BL, Cameron PM, Cuca GC, Davies P.
    J Immunol; 1993 Apr 01; 150(7):2844-57. PubMed ID: 8095956
    [Abstract] [Full Text] [Related]

  • 14. Crystallization and preliminary X-ray diffraction study of an idiotope-anti-idiotope Fv-Fv complex.
    Goldbaum FA, Fields BA, Cauerhff A, Ysern X, Houdusse A, Eisele JL, Poljak RJ, Mariuzza RA.
    J Mol Biol; 1994 Sep 02; 241(5):739-43. PubMed ID: 8071997
    [Abstract] [Full Text] [Related]

  • 15. Humanization of an anti-human IL-6 mouse monoclonal antibody glycosylated in its heavy chain variable region.
    Sato K, Ohtomo T, Hirata Y, Saito H, Matsuura T, Akimoto T, Akamatsu K, Koishihara Y, Ohsugi Y, Tsuchiya M.
    Hum Antibodies Hybridomas; 1996 Sep 02; 7(4):175-83. PubMed ID: 9140729
    [Abstract] [Full Text] [Related]

  • 16. Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding.
    Bhat TN, Bentley GA, Fischmann TO, Boulot G, Poljak RJ.
    Nature; 1990 Oct 04; 347(6292):483-5. PubMed ID: 2215663
    [Abstract] [Full Text] [Related]

  • 17. Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes.
    Schulze-Gahmen U, Rini JM, Wilson IA.
    J Mol Biol; 1993 Dec 20; 234(4):1098-118. PubMed ID: 8263915
    [Abstract] [Full Text] [Related]

  • 18. The third IgG-binding domain from streptococcal protein G. An analysis by X-ray crystallography of the structure alone and in a complex with Fab.
    Derrick JP, Wigley DB.
    J Mol Biol; 1994 Nov 11; 243(5):906-18. PubMed ID: 7966308
    [Abstract] [Full Text] [Related]

  • 19. The variable domain glycosylation in a monoclonal antibody specific to GnRH modulates antigen binding.
    Khurana S, Raghunathan V, Salunke DM.
    Biochem Biophys Res Commun; 1997 May 19; 234(2):465-9. PubMed ID: 9177294
    [Abstract] [Full Text] [Related]

  • 20. Crystal structure of an antigen-binding fragment bound to single-stranded DNA.
    Tanner JJ, Komissarov AA, Deutscher SL.
    J Mol Biol; 2001 Dec 07; 314(4):807-22. PubMed ID: 11733999
    [Abstract] [Full Text] [Related]

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