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Journal Abstract Search

129 related items for PubMed ID: 7917903

  • 1. Oxygen dependence of the cytotoxicity and metabolic activation of 4-alkylamino-5-nitroquinoline bioreductive drugs.
    Siim BG, Atwell GJ, Wilson WR.
    Br J Cancer; 1994 Oct; 70(4):596-603. PubMed ID: 7917903
    [Abstract] [Full Text] [Related]

  • 2. Metabolic and radiolytic reduction of 4-alkylamino-5-nitroquinoline bioreductive drugs. Relationship to hypoxia-selective cytotoxicity.
    Siim BG, Atwell GJ, Wilson WR.
    Biochem Pharmacol; 1994 Oct 18; 48(8):1593-604. PubMed ID: 7980625
    [Abstract] [Full Text] [Related]

  • 3. Hypoxia-selective antitumor agents. 15. Modification of rate of nitroreduction and extent of lysosomal uptake by polysubstitution of 4-(alkylamino)-5-nitroquinoline bioreductive drugs.
    Siim BG, Atwell GJ, Anderson RF, Wardman P, Pullen SM, Wilson WR, Denny WA.
    J Med Chem; 1997 Apr 25; 40(9):1381-90. PubMed ID: 9135035
    [Abstract] [Full Text] [Related]

  • 4. Efficient redox cycling of nitroquinoline bioreductive drugs due to aerobic nitroreduction in Chinese hamster cells.
    Siim BG, Wilson WR.
    Biochem Pharmacol; 1995 Jun 29; 50(1):75-82. PubMed ID: 7605348
    [Abstract] [Full Text] [Related]

  • 5. Does DNA targeting affect the cytotoxicity and cell uptake of basic nitroquinoline bioreductive drugs?
    Siim BG, Denny WA, Wilson WR.
    Int J Radiat Oncol Biol Phys; 1994 May 15; 29(2):311-5. PubMed ID: 8195025
    [Abstract] [Full Text] [Related]

  • 6. Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide.
    Wilson WR, Van Zijl P, Denny WA.
    Int J Radiat Oncol Biol Phys; 1992 May 15; 22(4):693-6. PubMed ID: 1544839
    [Abstract] [Full Text] [Related]

  • 7. Exploiting tumor hypoxia through bioreductive release of diffusible cytotoxins: the cobalt(III)-nitrogen mustard complex SN 24771.
    Wilson WR, Moselen JW, Cliffe S, Denny WA, Ware DC.
    Int J Radiat Oncol Biol Phys; 1994 May 15; 29(2):323-7. PubMed ID: 8195027
    [Abstract] [Full Text] [Related]

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  • 9. N-[2-(2-methyl-5-nitroimidazolyl)ethyl]-4-(2-nitroimidazolyl)butanamide (NSC 639862), a bisnitroimidazole with enhanced selectivity as a bioreductive drug.
    Moselen JW, Hay MP, Denny WA, Wilson WR.
    Cancer Res; 1995 Feb 01; 55(3):574-80. PubMed ID: 7834627
    [Abstract] [Full Text] [Related]

  • 10. The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline.
    Paragas EM, Humphreys SC, Min J, Joswig-Jones CA, Jones JP.
    Biochem Pharmacol; 2017 Dec 01; 145():210-217. PubMed ID: 28888950
    [Abstract] [Full Text] [Related]

  • 11. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 01; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 12. Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.
    Denny WA, Atwell GJ, Roberts PB, Anderson RF, Boyd M, Lock CJ, Wilson WR.
    J Med Chem; 1992 Dec 25; 35(26):4832-41. PubMed ID: 1479583
    [Abstract] [Full Text] [Related]

  • 13. Caffeine inhibition of the metabolic activation of a carcinogen, 4-nitroquinoline-1-oxide, in cultured Chinese hamster cells.
    Tsuda H, Yoshida D, Mizusaki S.
    Carcinogenesis; 1984 Mar 25; 5(3):331-4. PubMed ID: 6200248
    [Abstract] [Full Text] [Related]

  • 14. The effect of hypoxia on cytotoxicity, accumulation and DNA binding of cisplatin in Chinese hamster ovary cells.
    Matthews JB, Adomat H, Skov KA.
    Anticancer Drugs; 1993 Aug 25; 4(4):463-70. PubMed ID: 8400349
    [Abstract] [Full Text] [Related]

  • 15. Oxygen dependence of the cytotoxicity of the enediyne anti-tumour antibiotic esperamicin A1.
    Batchelder RM, Wilson WR, Hay MP, Denny WA.
    Br J Cancer Suppl; 1996 Jul 25; 27():S52-6. PubMed ID: 8763846
    [Abstract] [Full Text] [Related]

  • 16. Hypoxia-selective antitumor agents. 12. Nitrobenzyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine.
    Tercel M, Wilson WR, Anderson RF, Denny WA.
    J Med Chem; 1996 Mar 01; 39(5):1084-94. PubMed ID: 8676343
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug 01; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 18. Oxygen and exposure kinetics as factors influencing the cytotoxicity of porfiromycin, a mitomycin C analogue, in Chinese hamster ovary cells.
    Marshall RS, Rauth AM.
    Cancer Res; 1988 Oct 15; 48(20):5655-9. PubMed ID: 3167822
    [Abstract] [Full Text] [Related]

  • 19. Relationship between sensitivity of cells from patients with hereditary cutaneous malignant melanoma to killing and mutations by 4-nitroquinoline 1-oxide and adduct formation.
    Sato K, Howell JN, Greene MH, Maher VM, McCormick JJ.
    Cancer Res; 1988 Sep 15; 48(18):5145-50. PubMed ID: 3136916
    [Abstract] [Full Text] [Related]

  • 20. Unusual oxygen concentration dependence of toxicity of SR-4233, a hypoxic cell toxin.
    Koch CJ.
    Cancer Res; 1993 Sep 01; 53(17):3992-7. PubMed ID: 8358728
    [Abstract] [Full Text] [Related]

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