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3. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine. Dolan ME, Pegg AE, Dumenco LL, Moschel RC, Gerson SL. Carcinogenesis; 1991 Dec; 12(12):2305-9. PubMed ID: 1747932 [Abstract] [Full Text] [Related]
4. Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Dolan ME, Moschel RC, Pegg AE. Proc Natl Acad Sci U S A; 1990 Jul; 87(14):5368-72. PubMed ID: 2164681 [Abstract] [Full Text] [Related]
6. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea. Dolan ME, Stine L, Mitchell RB, Moschel RC, Pegg AE. Cancer Commun; 1990 Jul; 2(11):371-7. PubMed ID: 2242301 [Abstract] [Full Text] [Related]
9. Effect of DNA on the inactivation of O6-alkylguanine-DNA alkyltransferase by 9-substituted O6-benzylguanine derivatives. Pegg AE, Chung L, Moschel RC. Biochem Pharmacol; 1997 May 15; 53(10):1559-64. PubMed ID: 9260884 [Abstract] [Full Text] [Related]
10. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities. Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME. J Pharmacol Exp Ther; 2005 Dec 15; 315(3):1247-55. PubMed ID: 16126841 [Abstract] [Full Text] [Related]
11. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea. Loktionova NA, Pegg AE. Cancer Res; 1996 Apr 01; 56(7):1578-83. PubMed ID: 8603405 [Abstract] [Full Text] [Related]
12. Inactivation of O6-alkylguanine-DNA alkyltransferase by 8-substituted O6-benzylguanine analogs in mice. Ewesuedo RB, Wilson LR, Friedman HS, Moschel RC, Dolan ME. Cancer Chemother Pharmacol; 2001 Apr 01; 47(1):63-9. PubMed ID: 11221964 [Abstract] [Full Text] [Related]
16. 8-Substituted O6-benzylguanine, substituted 6(4)-(benzyloxy)pyrimidine, and related derivatives as inactivators of human O6-alkylguanine-DNA alkyltransferase. Chae MY, Swenn K, Kanugula S, Dolan ME, Pegg AE, Moschel RC. J Med Chem; 1995 Jan 20; 38(2):359-65. PubMed ID: 7830279 [Abstract] [Full Text] [Related]
17. Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine. Crone TM, Goodtzova K, Edara S, Pegg AE. Cancer Res; 1994 Dec 01; 54(23):6221-7. PubMed ID: 7954470 [Abstract] [Full Text] [Related]
18. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine. Crone TM, Pegg AE. Cancer Res; 1993 Oct 15; 53(20):4750-3. PubMed ID: 8402653 [Abstract] [Full Text] [Related]
19. Activation of human O6-alkylguanine-DNA alkyltransferase by DNA. Goodtzova K, Crone TM, Pegg AE. Biochemistry; 1994 Jul 19; 33(28):8385-90. PubMed ID: 8031773 [Abstract] [Full Text] [Related]
20. Effects of inhibition of O6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea. Lijinsky W, Pegg AE, Anver MR, Moschel RC. Jpn J Cancer Res; 1994 Mar 19; 85(3):226-30. PubMed ID: 8188519 [Abstract] [Full Text] [Related] Page: [Next] [New Search]