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Journal Abstract Search

129 related items for PubMed ID: 7923467

  • 1. Synthesis and structure-activity relationships of 7-[3-(1-aminoalkyl)pyrrolidinyl]- and 7-[3-1-aminocycloalkyl)pyrrolidinyl]-quinolone antibacterials.
    Kimura Y, Atarashi S, Takahashi M, Hayakawa I.
    Chem Pharm Bull (Tokyo); 1994 Jul; 42(7):1442-54. PubMed ID: 7923467
    [Abstract] [Full Text] [Related]

  • 2. Quinolone antibacterials containing the new 7-[3-(1-aminoethyl)-1- pyrrolidinyl] side chain: the effects of the 1-aminoethyl moiety and its stereochemical configurations on potency and in vivo efficacy.
    Domagala JM, Hagen SE, Joannides T, Kiely JS, Laborde E, Schroeder MC, Sesnie JA, Shapiro MA, Suto MJ, Vanderroest S.
    J Med Chem; 1993 Apr 02; 36(7):871-82. PubMed ID: 8385225
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and antibacterial activity of new quinolones containing a 7-[3-(1-amino-1-methylethyl)-1-pyrrolidinyl] moiety. Gram-positive agents with excellent oral activity and low side-effect potential.
    Hagen SE, Domagala JM, Gracheck SJ, Sesnie JA, Stier MA, Suto MJ.
    J Med Chem; 1994 Mar 18; 37(6):733-8. PubMed ID: 8145222
    [Abstract] [Full Text] [Related]

  • 4. Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents.
    Atarashi S, Imamura M, Kimura Y, Yoshida A, Hayakawa I.
    J Med Chem; 1993 Oct 29; 36(22):3444-8. PubMed ID: 8230135
    [Abstract] [Full Text] [Related]

  • 5. (Fluorocyclopropyl)quinolones. 2. Synthesis and Stereochemical structure-activity relationships of chiral 7-(7-amino-5-azaspiro[2.4]heptan-5-yl)-1-(2-fluorocyclopropyl)quinolone antibacterial agents.
    Kimura Y, Atarashi S, Kawakami K, Sato K, Hayakawa I.
    J Med Chem; 1994 Sep 30; 37(20):3344-52. PubMed ID: 7932562
    [Abstract] [Full Text] [Related]

  • 6. 5-Amino-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4- dihydro-4-oxo-3-quinolinecarboxylic acid (PD 124,816). Synthesis and biological evaluation of a new class of quinolone antibacterials.
    Domagala JM, Hagen SE, Hutt MP, Sanchez JP, Sesnie J, Trehan AK.
    Drugs Exp Clin Res; 1988 Sep 30; 14(7):453-60. PubMed ID: 2853667
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships in quinolone antibacterials: design, synthesis and biological activities of novel isothiazoloquinolones.
    Chu DT, Fernandes PB, Claiborne AK, Shen L, Pernet AG.
    Drugs Exp Clin Res; 1988 Sep 30; 14(6):379-83. PubMed ID: 2850902
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and antibacterial activity of novel 7-(3-substituted-3 or 4-trifluoromethyl-1-pyrrolidinyl)-8-methoxyfluoroquinolones.
    Fukui H, Shibata T, Naito T, Nakano J, Maejima T, Senda H, Iwatani W, Tatsumi Y, Suda M, Arika T.
    Bioorg Med Chem Lett; 1998 Oct 20; 8(20):2833-8. PubMed ID: 9873632
    [Abstract] [Full Text] [Related]

  • 9. Quinolone antibacterials: synthesis and biological activity of carbon isosteres of the 1-piperazinyl and 3-amino-1-pyrrolidinyl side chains.
    Laborde E, Kiely JS, Culbertson TP, Lesheski LE.
    J Med Chem; 1993 Jul 09; 36(14):1964-70. PubMed ID: 8393112
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and antimicrobial evaluation of a series of 7-[3-amino (or aminomethyl)-4-aryl (or cyclopropyl)-1-pyrrolidinyl]-4-quinolone- and -1,8-naphthyridone-3-carboxylic acids.
    Bucsh RA, Domagala JM, Laborde E, Sesnie JC.
    J Med Chem; 1993 Dec 24; 36(26):4139-51. PubMed ID: 8277495
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and antibacterial activity of novel pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid derivatives carrying the 3-cyclopropylaminomethyl-4-substituted-1-pyrrolidinyl group as a C-10 substituent.
    Asahina Y, Takei M, Kimura T, Fukuda Y.
    J Med Chem; 2008 Jun 12; 51(11):3238-49. PubMed ID: 18457383
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and antibacterial activity of new tetracyclic quinolone antibacterials.
    Taguchi M, Kondo H, Inoue Y, Kawahata Y, Jinbo Y, Sakamoto F, Tsukamoto G.
    J Med Chem; 1992 Jan 12; 35(1):94-9. PubMed ID: 1310116
    [Abstract] [Full Text] [Related]

  • 13. 7-(2-Aminomethyl-1-azetidinyl)-4-oxoquinoline-3-carboxylic acids as potent antibacterial agents: design, synthesis, and antibacterial activity.
    Fujita M, Chiba K, Tominaga Y, Hino K.
    Chem Pharm Bull (Tokyo); 1998 May 12; 46(5):787-96. PubMed ID: 9621413
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and in vitro activity of new methylenepiperidinyl and methylenepyrrolidinyl oxazolidinone antibacterial agents.
    Kim HY, Lee JS, Cha JH, Pae AN, Cho YS, Chang MH, Koh HY.
    Bioorg Med Chem Lett; 2003 Jul 07; 13(13):2227-30. PubMed ID: 12798339
    [Abstract] [Full Text] [Related]

  • 15. In vitro antibacterial activity of FA103, a new quinolone derivative of C-7 position with 7-perhydrodiazepinone.
    Imamori K, Asaoka T, Matsumoto M, Maebashi K, Matsuda H, Tahara Y.
    Jpn J Antibiot; 1995 Dec 07; 48(12):1891-8. PubMed ID: 8587163
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and in vitro antibacterial activity of some N-(5-aryl-1,3,4-thiadiazole-2-yl)piperazinyl quinolone derivatives.
    Foroumadi A, Soltani F, Moshafi MH, Ashraf-Askari R.
    Farmaco; 2003 Oct 07; 58(10):1023-8. PubMed ID: 14505733
    [Abstract] [Full Text] [Related]

  • 17. Novel fluoroquinolone antibacterial agents containing oxime-substituted (aminomethyl)pyrrolidines: synthesis and antibacterial activity of 7-(4-(aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6- fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid (LB20304).
    Hong CY, Kim YK, Chang JH, Kim SH, Choi H, Nam DH, Kim YZ, Kwak JH.
    J Med Chem; 1997 Oct 24; 40(22):3584-93. PubMed ID: 9357525
    [Abstract] [Full Text] [Related]

  • 18. Imidazo- and triazoloquinolones as antibacterial agents. Synthesis and structure-activity relationships.
    Fujita M, Egawa H, Kataoka M, Miyamoto T, Nakano J, Matsumoto J.
    Chem Pharm Bull (Tokyo); 1995 Dec 24; 43(12):2123-32. PubMed ID: 8582014
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and in vitro antibacterial activity of N-[5-(5-nitro-2-furyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolone derivatives.
    Foroumadi A, Ashraf-Askari R, Moshafi MH, Emami S, Zeynali A.
    Pharmazie; 2003 Jun 24; 58(6):432-3. PubMed ID: 12857013
    [No Abstract] [Full Text] [Related]

  • 20. New trifluoromethyl quinolone derivatives: synthesis and investigation of antimicrobial properties.
    Panda SS, Jain SC.
    Bioorg Med Chem Lett; 2013 Jun 01; 23(11):3225-9. PubMed ID: 23611733
    [Abstract] [Full Text] [Related]

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