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142 related items for PubMed ID: 7923480

  • 1. Inhibitors of sterol synthesis: synthesis and spectral properties of derivatives of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one fluorinated at carbon 7 or carbon 9 and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Siddiqui AU, Swaminathan S, Pinkerton FD, Gerst N, Wilson WK, Choi H, Schroephfer GJ.
    Chem Phys Lipids; 1994 Jun 24; 72(1):59-75. PubMed ID: 7923480
    [Abstract] [Full Text] [Related]

  • 2. Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Swaminathan S, Wilson WK, Pinkerton FD, Gerst N, Ramser M, Schroepfer GJ.
    J Lipid Res; 1993 Oct 24; 34(10):1805-23. PubMed ID: 8245728
    [Abstract] [Full Text] [Related]

  • 3. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholesta-8(14),24-dien-15-one, 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, and 3 beta,24-dihydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Swaminathan S, Pinkerton FD, Numazawa S, Wilson WK, Schroepfer GJ.
    J Lipid Res; 1992 Oct 24; 33(10):1503-15. PubMed ID: 1431575
    [Abstract] [Full Text] [Related]

  • 4. Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Siddiqui AU, Wilson WK, Ruecker KE, Pinkerton FD, Schroepfer GJ.
    Chem Phys Lipids; 1992 Nov 24; 63(1-2):77-90. PubMed ID: 1486662
    [Abstract] [Full Text] [Related]

  • 5. Inhibitors of sterol synthesis. Characterization of trimethylsilyl dienol ethers of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one. Applications in the analysis of mitochondrial metabolites of the 15-ketosterol by gas chromatography-mass spectrometry.
    St Pyrek J, Wilson WK, Numazawa S, Schoepfer GJ.
    J Lipid Res; 1991 Aug 24; 32(8):1371-80. PubMed ID: 1770319
    [Abstract] [Full Text] [Related]

  • 6. Inhibitors of sterol synthesis. Characterization of beta,gamma-unsaturated analogs of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK, Wheeler ME, Pinkerton FD, St Pyrek J, Schroepfer GJ.
    J Lipid Res; 1991 Jul 24; 32(7):1215-27. PubMed ID: 1940644
    [Abstract] [Full Text] [Related]

  • 7. Inhibitors of sterol synthesis. Chemical synthesis of 7 alpha-ethyl and 16 alpha-ethyl derivatives of delta 8(14)-15-oxygenated sterols and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase in CHO-K1 cells.
    Kim HS, Wilson WK, Kirkpatrick ND, Pinkerton FD, Swaminathan S, Hylarides MD, Schroepfer GJ.
    Chem Phys Lipids; 1992 Jul 24; 62(1):55-67. PubMed ID: 1423803
    [Abstract] [Full Text] [Related]

  • 8. Inhibitors of sterol synthesis. Metabolism-based design and construction of a new analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects in cultured mammalian cells and in rats.
    Swaminathan S, Siddiqui AU, Gerst N, Pinkerton FD, Kisic A, Kim LJ, Wilson WK, Schroepfer GJ.
    J Lipid Res; 1995 Apr 24; 36(4):767-86. PubMed ID: 7616123
    [Abstract] [Full Text] [Related]

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  • 10. Sterol synthesis. Synthesis of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats.
    Carroll JN, Pinkerton FD, Su X, Gerst N, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1998 Aug 24; 94(2):209-25. PubMed ID: 9779586
    [Abstract] [Full Text] [Related]

  • 11. Inhibitors of sterol synthesis: effects of a 7 alpha-alkyl analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats.
    Siddiqui AU, Gerst N, Kim LJ, Pinkerton FD, Kisic A, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1994 Apr 19; 70(2):163-78. PubMed ID: 8033288
    [Abstract] [Full Text] [Related]

  • 12. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholestan-15-one.
    Siddiqui AU, Swaminathan S, Su X, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1997 Apr 25; 86(2):95-119. PubMed ID: 9179993
    [Abstract] [Full Text] [Related]

  • 13. Inhibitors of sterol biosynthesis. Carbon-13 nuclear magnetic resonance studies of 9 alpha-fluoro-5 alpha-cholest-8(14)-en-3 beta-ol-15-one and related compounds.
    Tsuda M, Schroepfer GJ.
    J Lipid Res; 1981 Nov 25; 22(8):1188-97. PubMed ID: 7320629
    [Abstract] [Full Text] [Related]

  • 14. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5 alpha-cholest-8(14)-ene-3 beta,15 beta,26-triol, a potential metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells.
    Swaminathan S, Pinkerton FD, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1992 May 25; 61(3):235-42. PubMed ID: 1525963
    [Abstract] [Full Text] [Related]

  • 15. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-24-dimethylamino-5 alpha-chol-8(14)-en-15-one and its effects on HMG-CoA reductase activity in CHO-K1 cells.
    Herz JE, Wilson WK, Pinkerton FD, Schroepfer GJ.
    Chem Phys Lipids; 1991 Nov 25; 60(1):61-9. PubMed ID: 1813179
    [Abstract] [Full Text] [Related]

  • 16. Inhibitors of sterol synthesis. Spectral characterization of derivatives of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
    St Pyrek J, Wilson WK, Schroepfer GJ.
    J Lipid Res; 1987 Nov 25; 28(11):1296-307. PubMed ID: 3430060
    [Abstract] [Full Text] [Related]

  • 17. Inhibitors of sterol synthesis. Effects of fluorine substitution at carbon atom 25 of cholesterol on its spectral and chromatographic properties and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK, Swaminathan S, Pinkerton FD, Gerst N, Schroepfer GJ.
    Steroids; 1994 May 25; 59(5):310-7. PubMed ID: 8073444
    [Abstract] [Full Text] [Related]

  • 18. Inhibitors of sterol synthesis. An improved chemical synthesis of 26-oxygenated delta 8(14)-15-ketosterols having the 25R configuration.
    Siddiqui AU, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1994 May 23; 71(2):205-18. PubMed ID: 8076403
    [Abstract] [Full Text] [Related]

  • 19. Sterol synthesis. Preparation and characterization of fluorinated and deuterated analogs of oxygenated derivatives of cholesterol.
    Li S, Pang J, Wilson WK, Schroepfer GJ.
    Chem Phys Lipids; 1999 May 23; 99(1):33-71. PubMed ID: 10377963
    [Abstract] [Full Text] [Related]

  • 20. Inhibitors of sterol synthesis. Effects of a new fluorinated analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one in rats.
    Gerst N, Pinkerton FD, Kisic A, Wilson WK, Swaminathan S, Schroepfer GJ.
    J Lipid Res; 1994 Jun 23; 35(6):1040-56. PubMed ID: 8077843
    [Abstract] [Full Text] [Related]

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