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Journal Abstract Search

142 related items for PubMed ID: 7923480

  • 21. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholestan-15-one and its 17 beta-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
    Siddiqui AU, Wilson WK, Parish EJ, Gerst N, Pinkerton FD, Schroepfer GJ.
    Chem Phys Lipids; 1994 Oct 20; 74(1):1-15. PubMed ID: 7820900
    [Abstract] [Full Text] [Related]

  • 22. Metabolism of a novel side chain modified Delta8(14)-15-ketosterol, a potential cholesterol lowering drug: 28-hydroxylation by CYP27A1.
    Pettersson H, Norlin M, Andersson U, Pikuleva I, Björkhem I, Misharin AY, Wikvall K.
    Biochim Biophys Acta; 2008 Aug 20; 1781(8):383-90. PubMed ID: 18603016
    [Abstract] [Full Text] [Related]

  • 23. Inhibitors of sterol synthesis. 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, an active metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one.
    Swaminathan S, Pinkerton FD, Schroepfer GJ.
    J Med Chem; 1992 Feb 21; 35(4):793-5. PubMed ID: 1542104
    [No Abstract] [Full Text] [Related]

  • 24. Chemical synthesis of 15-ketosterols and their inhibitions of cholesteryl ester transfer protein.
    Kim HS, Oh SH, Kim DI, Kim IC, Cho KH, Park YB.
    Bioorg Med Chem; 1995 Apr 21; 3(4):367-74. PubMed ID: 8581419
    [Abstract] [Full Text] [Related]

  • 25. Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Schroepfer GJ, Parish EJ, Tsuda M, Kandutsch AA.
    Chem Phys Lipids; 1988 Jul 21; 47(3):187-207. PubMed ID: 3168085
    [Abstract] [Full Text] [Related]

  • 26. Inhibitors of sterol synthesis. Chemical synthesis, structure, and biological activities of (25R)-3 beta,26-dihydroxy-5 alpha-cholest-8(14)-en-15-one, a metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one.
    Kim HS, Wilson WK, Needleman DH, Pinkerton FD, Wilson DK, Quiocho FA, Schroepfer GJ.
    J Lipid Res; 1989 Feb 21; 30(2):247-61. PubMed ID: 2715729
    [Abstract] [Full Text] [Related]

  • 27. Inhibitors of sterol synthesis: 3 beta-hydroxy-25,26,26,26,27,27,27- heptafluoro-5 alpha-cholestan-15-one, an analog of a potent hypocholesterolemic agent in which its major metabolism is blocked.
    Swaminathan S, Siddiqui AU, Pinkerton FD, Gerst N, Wilson WK, Schroepfer GJ.
    Biochem Biophys Res Commun; 1994 May 30; 201(1):168-73. PubMed ID: 8198571
    [Abstract] [Full Text] [Related]

  • 28. Inhibitors of cholesterol biosynthesis. Further studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in rat liver preparations.
    Monger DJ, Schroepfer GJ.
    Chem Phys Lipids; 1988 May 30; 47(1):21-46. PubMed ID: 3396133
    [Abstract] [Full Text] [Related]

  • 29. Inhibitors of sterol synthesis. Studies of the metabolism of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one in Chinese hamster ovary cells and its effects on activities of early enzymes in cholesterol biosynthesis.
    Pajewski TN, Pinkerton FD, Miller LR, Schroepfer GJ.
    Chem Phys Lipids; 1988 Oct 30; 48(3-4):153-68. PubMed ID: 2907421
    [Abstract] [Full Text] [Related]

  • 30. Inhibitors of sterol synthesis. Chemical synthesis of 5 beta-cholest-8-ene-3 beta,15 alpha-diol and its effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK, Pinkerton FD, Kirkpatrick ND, Schroepfer GJ.
    J Lipid Res; 1989 Jun 30; 30(6):919-28. PubMed ID: 2794782
    [Abstract] [Full Text] [Related]

  • 31. Concerning the chemical synthesis of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one, a novel regulator of cholesterol metabolism.
    Wilson WK, Wang KS, Kisic A, Schroepfer GJ.
    Chem Phys Lipids; 1988 Sep 30; 48(1-2):7-17. PubMed ID: 3208416
    [Abstract] [Full Text] [Related]

  • 32. Synthesis of 3 beta-hydroxy-5 alpha-cholest-8-en-7-one and 3 beta-hydroxy-5 alpha-cholest-8-en-11-one: evaluation as potential hypocholesterolemic agents.
    Parish EJ, Nanduri VB, Seikel JM, Kohl HH, Nusbaum KE.
    Steroids; 1986 Sep 30; 48(5-6):407-18. PubMed ID: 3445290
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  • 35. Inhibitors of sterol biosynthesis. Synthesis and activities of ring C oxygenated sterols.
    Schroepfer GJ, Parish EJ, Kandutsch AA.
    Chem Phys Lipids; 1988 Feb 30; 46(2):147-54. PubMed ID: 3342458
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  • 40. Synergistic action of two oxysterols in the lowering of HMG-CoA reductase activity in CHO-K1 cells.
    Pinkerton FD, Pelley RP, Schroepfer GJ.
    Biochem Biophys Res Commun; 1992 Jul 15; 186(1):569-73. PubMed ID: 1632792
    [Abstract] [Full Text] [Related]

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