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Journal Abstract Search

376 related items for PubMed ID: 7923572

  • 1. Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity.
    Seaton MJ, Schlosser PM, Bond JA, Medinsky MA.
    Carcinogenesis; 1994 Sep; 15(9):1799-806. PubMed ID: 7923572
    [Abstract] [Full Text] [Related]

  • 2. Benzene metabolism by reconstituted cytochromes P450 2B1 and 2E1 and its modulation by cytochrome b5, microsomal epoxide hydrolase, and glutathione transferases: evidence for an important role of microsomal epoxide hydrolase in the formation of hydroquinone.
    Snyder R, Chepiga T, Yang CS, Thomas H, Platt K, Oesch F.
    Toxicol Appl Pharmacol; 1993 Oct; 122(2):172-81. PubMed ID: 8211999
    [Abstract] [Full Text] [Related]

  • 3. Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochromes P450 2E1 and 3A4 and human, mouse and rat liver microsomes.
    Seaton MJ, Follansbee MH, Bond JA.
    Carcinogenesis; 1995 Oct; 16(10):2287-93. PubMed ID: 7586124
    [Abstract] [Full Text] [Related]

  • 4. In vitro conjugation of benzene metabolites by human liver: potential influence of interindividual variability on benzene toxicity.
    Seaton MJ, Schlosser P, Medinsky MA.
    Carcinogenesis; 1995 Jul; 16(7):1519-27. PubMed ID: 7614685
    [Abstract] [Full Text] [Related]

  • 5. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.
    Kharasch ED, Thummel KE.
    Anesthesiology; 1993 Oct; 79(4):795-807. PubMed ID: 8214760
    [Abstract] [Full Text] [Related]

  • 6. Differences in rates of benzene metabolism correlate with observed genotoxicity.
    Kenyon EM, Kraichely RE, Hudson KT, Medinsky MA.
    Toxicol Appl Pharmacol; 1996 Jan; 136(1):49-56. PubMed ID: 8560479
    [Abstract] [Full Text] [Related]

  • 7. Human liver microsomes are efficient catalysts of 1,3-butadiene oxidation: evidence for major roles by cytochromes P450 2A6 and 2E1.
    Duescher RJ, Elfarra AA.
    Arch Biochem Biophys; 1994 Jun; 311(2):342-9. PubMed ID: 8203896
    [Abstract] [Full Text] [Related]

  • 8. Metabolism of the chlorofluorocarbon substitute 1,1-dichloro-2,2,2-trifluoroethane by rat and human liver microsomes: the role of cytochrome P450 2E1.
    Urban G, Speerschneider P, Dekant W.
    Chem Res Toxicol; 1994 Jun; 7(2):170-6. PubMed ID: 8199305
    [Abstract] [Full Text] [Related]

  • 9. Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether.
    Köster U, Speerschneider P, Kerssebaum R, Wittmann H, Dekant W.
    Drug Metab Dispos; 1994 Jun; 22(5):667-72. PubMed ID: 7835215
    [Abstract] [Full Text] [Related]

  • 10. The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
    Dekant W, Assmann M, Urban G.
    Toxicol Appl Pharmacol; 1995 Dec; 135(2):200-7. PubMed ID: 8545828
    [Abstract] [Full Text] [Related]

  • 11. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 12. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes.
    Clarke SE, Baldwin SJ, Bloomer JC, Ayrton AD, Sozio RS, Chenery RJ.
    Chem Res Toxicol; 1994 Feb; 7(6):836-42. PubMed ID: 7696540
    [Abstract] [Full Text] [Related]

  • 13. Comparative studies of the in vitro metabolism and covalent binding of 14C-benzene by liver slices and microsomal fraction of mouse, rat, and human.
    Brodfuehrer JI, Chapman DE, Wilke TJ, Powis G.
    Drug Metab Dispos; 1990 Feb; 18(1):20-7. PubMed ID: 1970773
    [Abstract] [Full Text] [Related]

  • 14. Use of a mathematical model of rodent in vitro benzene metabolism to predict human in vitro metabolism data.
    Lovern MR, Maris ME, Schlosser PM.
    Carcinogenesis; 1999 Aug; 20(8):1511-20. PubMed ID: 10426800
    [Abstract] [Full Text] [Related]

  • 15. Benzene and phenol metabolism by mouse and rat liver microsomes.
    Schlosser PM, Bond JA, Medinsky MA.
    Carcinogenesis; 1993 Dec; 14(12):2477-86. PubMed ID: 8269615
    [Abstract] [Full Text] [Related]

  • 16. Catalytic properties of the human cytochrome P450 2E1 produced by cDNA expression in mammalian cells.
    Patten CJ, Ishizaki H, Aoyama T, Lee M, Ning SM, Huang W, Gonzalez FJ, Yang CS.
    Arch Biochem Biophys; 1992 Nov 15; 299(1):163-71. PubMed ID: 1444447
    [Abstract] [Full Text] [Related]

  • 17. Cytochrome P450 mediated bioactivation of methyleugenol to 1'-hydroxymethyleugenol in Fischer 344 rat and human liver microsomes.
    Gardner I, Wakazono H, Bergin P, de Waziers I, Beaune P, Kenna JG, Caldwell J.
    Carcinogenesis; 1997 Sep 15; 18(9):1775-83. PubMed ID: 9328175
    [Abstract] [Full Text] [Related]

  • 18. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Oct 15; 13(10):1789-94. PubMed ID: 1423839
    [Abstract] [Full Text] [Related]

  • 19. Oxidative and reductive metabolism by cytochrome P450 2E1.
    Koop DR.
    FASEB J; 1992 Jan 06; 6(2):724-30. PubMed ID: 1537462
    [Abstract] [Full Text] [Related]

  • 20. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A, Satoh H, Thomas PE, Bush E, Moore D.
    Drug Metab Dispos; 1996 Sep 06; 24(9):940-7. PubMed ID: 8886602
    [Abstract] [Full Text] [Related]

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