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Journal Abstract Search

170 related items for PubMed ID: 7929041

  • 1. Alterations of the regiospecificity of progesterone metabolism by the mutagenesis of two key amino acid residues in rabbit cytochrome P450 2C3v.
    Richardson TH, Johnson EF.
    J Biol Chem; 1994 Sep 30; 269(39):23937-43. PubMed ID: 7929041
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  • 2. A single amino acid substitution confers progesterone 6 beta-hydroxylase activity to rabbit cytochrome P450 2C3.
    Hsu MH, Griffin KJ, Wang Y, Kemper B, Johnson EF.
    J Biol Chem; 1993 Apr 05; 268(10):6939-44. PubMed ID: 8463225
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  • 3. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity.
    Straub P, Johnson EF, Kemper B.
    Arch Biochem Biophys; 1993 Nov 01; 306(2):521-7. PubMed ID: 8215458
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  • 4. Role of residues 363 and 206 in conversion of cytochrome P450 2B1 from a steroid 16-hydroxylase to a 15 alpha-hydroxylase.
    Luo Z, He YA, Halpert JR.
    Arch Biochem Biophys; 1994 Feb 15; 309(1):52-7. PubMed ID: 8117113
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  • 5. Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11.
    Liu J, He YA, Halpert JR.
    Arch Biochem Biophys; 1996 Mar 01; 327(1):167-73. PubMed ID: 8615687
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  • 8. Interconversion of the androstenedione hydroxylase specificities of cytochromes P450 2B4 and 2B5 upon simultaneous site-directed mutagenesis of four key substrate recognition residues.
    He YQ, Szklarz GD, Halpert JR.
    Arch Biochem Biophys; 1996 Nov 01; 335(1):152-60. PubMed ID: 8914846
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  • 11. Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.
    He YA, He YQ, Szklarz GD, Halpert JR.
    Biochemistry; 1997 Jul 22; 36(29):8831-9. PubMed ID: 9220969
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  • 12. Constitutive forms of rabbit-liver microsomal cytochrome P-450: enzymatic diversity, polymorphism and allosteric regulation.
    Johnson EF, Schwab GE.
    Xenobiotica; 1984 Jul 22; 14(1-2):3-18. PubMed ID: 6609490
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  • 13. Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.
    Szklarz GD, He YQ, Kedzie KM, Halpert JR, Burnett VL.
    Arch Biochem Biophys; 1996 Mar 15; 327(2):308-18. PubMed ID: 8619620
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  • 14. Point mutations at threonine-301 modify substrate specificity of rabbit liver microsomal cytochromes P-450 (laurate (omega-1)-hydroxylase and testosterone 16 alpha-hydroxylase).
    Imai Y, Nakamura M.
    Biochem Biophys Res Commun; 1989 Feb 15; 158(3):717-22. PubMed ID: 2493247
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  • 15. Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.
    Iwasaki M, Lindberg RL, Juvonen RO, Negishi M.
    Biochem J; 1993 Apr 15; 291 ( Pt 2)(Pt 2):569-73. PubMed ID: 8484736
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  • 16. Inactivation of Escherichia coli-expressed rabbit cytochrome P-450 2C enzymes by 17 beta-substituted steroids.
    Klekotka PA, Richardson TH, Johnson EF, Halpert JR.
    J Pharmacol Exp Ther; 1995 Sep 15; 274(3):1450-5. PubMed ID: 7562521
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  • 17. Altering the regiospecificity of androstenedione hydroxylase activity in P450s 2a-4/5 by a mutation of the residue at position 481.
    Iwasaki M, Darden TA, Pedersen LG, Negishi M.
    Biochemistry; 1995 Apr 18; 34(15):5054-9. PubMed ID: 7711025
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  • 19. Structural determinants of cytochrome P450 2B1 specificity: evidence for five substrate recognition sites.
    He Y, Luo Z, Klekotka PA, Burnett VL, Halpert JR.
    Biochemistry; 1994 Apr 12; 33(14):4419-24. PubMed ID: 8155660
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