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Journal Abstract Search


118 related items for PubMed ID: 7932558

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  • 2. Nonpeptidic inhibitors of human leukocyte elastase. 3. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of orally active 3-amino-6-phenylpyridin-2-one trifluoromethyl ketones.
    Bernstein PR, Andisik D, Bradley PK, Bryant CB, Ceccarelli C, Damewood JR, Earley R, Edwards PD, Feeney S, Gomes BC.
    J Med Chem; 1994 Sep 30; 37(20):3313-26. PubMed ID: 7932559
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  • 8. Non-peptidic inhibitors of human leukocyte elastase. 4. Design, synthesis, and in vitro and in vivo activity of a series of beta-carbolinone-containing trifluoromethyl ketones.
    Veale CA, Damewood JR, Steelman GB, Bryant C, Gomes B, Williams J.
    J Med Chem; 1995 Jan 06; 38(1):86-97. PubMed ID: 7837244
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  • 9. Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1.
    Skiles JW, Miao C, Sorcek R, Jacober S, Mui PW, Chow G, Weldon SM, Possanza G, Skoog M, Keirns J.
    J Med Chem; 1992 Dec 25; 35(26):4795-808. PubMed ID: 1479581
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  • 11. Inhibition of human leukocyte elastase by N-substituted tripeptide trifluoromethyl ketones.
    Skiles JW, Fuchs V, Chow G, Skoog M.
    Res Commun Chem Pathol Pharmacol; 1990 Jun 25; 68(3):365-74. PubMed ID: 2385759
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  • 12. Proline-valine pseudo peptide enol lactones. Effective and selective inhibitors of chymotrypsin and human leukocyte elastase.
    Reed PE, Katzenellenbogen JA.
    J Biol Chem; 1991 Jan 05; 266(1):13-21. PubMed ID: 1985887
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  • 13. Structure-activity studies of fluoroketone inhibitors of alpha-lytic protease and human leukocyte elastase.
    Govardhan CP, Abeles RH.
    Arch Biochem Biophys; 1990 Jul 05; 280(1):137-46. PubMed ID: 2353815
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  • 14. Specificity, stability, and potency of monocyclic beta-lactam inhibitors of human leucocyte elastase.
    Knight WB, Green BG, Chabin RM, Gale P, Maycock AL, Weston H, Kuo DW, Westler WM, Dorn CP, Finke PE.
    Biochemistry; 1992 Sep 08; 31(35):8160-70. PubMed ID: 1525156
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  • 15. Binding pockets on the surface of human leukocyte elastase and human leukocyte cathepsin G. Implications to the design of inhibitors derived from human C-reactive protein.
    Yavin EJ, Eisenstein M, Fridkin M.
    Biomed Pept Proteins Nucleic Acids; 1992 Sep 08; 2(3):71-8. PubMed ID: 9575343
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  • 16. 2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.
    Loughlin WA, Jenkins ID, Karis ND, Schweiker SS, Healy PC.
    Eur J Med Chem; 2016 Mar 23; 111():1-14. PubMed ID: 26851835
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  • 17. Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones.
    Shah SK, Dorn CP, Finke PE, Hale JJ, Hagmann WK, Brause KA, Chandler GO, Kissinger AL, Ashe BM, Weston H.
    J Med Chem; 1992 Oct 16; 35(21):3745-54. PubMed ID: 1433189
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  • 18. Substituted 2-pyrones, 2-pyridones, and other congeners of elasnin as potential agents for the treatment of chronic obstructive lung diseases.
    Groutas WC, Stanga MA, Brubaker MJ, Huang TL, Moi MK, Carroll RT.
    J Med Chem; 1985 Aug 16; 28(8):1106-9. PubMed ID: 3848491
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  • 19. Synthetic inhibitors of human leukocyte elastase, Part 3. Peptides with alkyl groups at the N- or C-terminus. Non-toxic competitive inhibitors of human leukocyte elastase.
    Lentini A, Farchione F, Ternai B, Kreua-Ongarjnukool N, Tovivich P.
    Biol Chem Hoppe Seyler; 1987 Apr 16; 368(4):369-78. PubMed ID: 3649243
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