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Journal Abstract Search

116 related items for PubMed ID: 7945403

  • 1. Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine.
    Navé JF, Eschbach A, Wolff-Kugel D, Halazy S, Balzarini J.
    Biochem Pharmacol; 1994 Sep 15; 48(6):1105-12. PubMed ID: 7945403
    [Abstract] [Full Text] [Related]

  • 2. Cellular phosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key intermediate in the activation of the antiviral agent DDI, in human peripheral blood mononuclear cells.
    Robbins BL, Greenhaw J, Fridland A.
    Nucleosides Nucleotides Nucleic Acids; 2000 Sep 15; 19(1-2):405-13. PubMed ID: 10772723
    [Abstract] [Full Text] [Related]

  • 3. Interpretation of the roles of adenylosuccinate lyase and of AMP deaminase in the anti-HIV activity of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
    Nair V, Sells TB.
    Biochim Biophys Acta; 1992 Feb 26; 1119(2):201-4. PubMed ID: 1540653
    [Abstract] [Full Text] [Related]

  • 4. 9-Beta-D-arabinofuranosyladenine 5'-monophosphate (araAMP) is converted directly to its antivirally active 5'-triphosphate form by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Balzarini J, De Clercq E.
    Biochem Biophys Res Commun; 1990 Dec 31; 173(3):781-7. PubMed ID: 1702630
    [Abstract] [Full Text] [Related]

  • 5. Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    Kewn S, Hoggard PG, Henry-Mowatt JS, Veal GJ, Sales SD, Barry MG, Back DJ.
    AIDS Res Hum Retroviruses; 1999 Jun 10; 15(9):793-802. PubMed ID: 10381167
    [Abstract] [Full Text] [Related]

  • 6. The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
    Cherney MM, Cherney LT, Garen CR, James MN.
    J Mol Biol; 2011 Nov 04; 413(4):844-56. PubMed ID: 21963988
    [Abstract] [Full Text] [Related]

  • 7. Conversion of acyclic nucleoside phosphonates to their diphosphate derivatives by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Balzarini J, De Clercq E.
    Adv Exp Med Biol; 1991 Nov 04; 309A():29-32. PubMed ID: 1665008
    [No Abstract] [Full Text] [Related]

  • 8. Determination of ddATP levels in human immunodeficiency virus-infected patients treated with dideoxyinosine.
    Le Saint C, Terreux R, Duval D, Durant J, Ettesse H, Dellamonica P, Guedj R, Vincent JP, Cupo A.
    Antimicrob Agents Chemother; 2004 Feb 04; 48(2):589-95. PubMed ID: 14742213
    [Abstract] [Full Text] [Related]

  • 9. Anomalous accumulation and decay of 2',3'-dideoxyadenosine-5'-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2',3'-dideoxyinosine.
    Ahluwalia G, Cooney DA, Hartman NR, Mitsuya H, Yarchoan R, Fridland A, Broder S, Johns DG.
    Drug Metab Dispos; 1993 Feb 04; 21(2):369-76. PubMed ID: 8097711
    [Abstract] [Full Text] [Related]

  • 10. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP, Nandy P, Avramis VI.
    In Vivo; 2000 Feb 04; 14(3):377-88. PubMed ID: 10904870
    [Abstract] [Full Text] [Related]

  • 11. Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity (phosphoribosyl diphosphate forming): dual role in phosphonate degradation and NAD biosynthesis pathways.
    Hove-Jensen B, Rosenkrantz TJ, Haldimann A, Wanner BL.
    J Bacteriol; 2003 May 04; 185(9):2793-801. PubMed ID: 12700258
    [Abstract] [Full Text] [Related]

  • 12. Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
    Hartman NR, Ahluwalia GS, Cooney DA, Mitsuya H, Kageyama S, Fridland A, Broder S, Johns DG.
    Mol Pharmacol; 1991 Jul 04; 40(1):118-24. PubMed ID: 1677450
    [Abstract] [Full Text] [Related]

  • 13. Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication.
    Placidi L, Faraj A, Loi AG, Pierra C, Egron D, Cretton-Scott E, Gosseli G, Périgaud C, Martin LT, Schinazi RF, Imbach JL, el Kouni MH, Bryant ML, Sommadossi JP.
    Antivir Chem Chemother; 2001 Mar 04; 12(2):99-108. PubMed ID: 11527047
    [Abstract] [Full Text] [Related]

  • 14. Uptake and distribution of 2',3'-dideoxyinosine and its derivatives in a human monocytoid cell line.
    Vázquez-Padua MA, Mayol N, López M.
    Cell Mol Biol (Noisy-le-grand); 1995 Mar 04; 41 Suppl 1():S113-9. PubMed ID: 8574139
    [Abstract] [Full Text] [Related]

  • 15. Phosphorylation of 2',3'-dideoxyinosine by cytosolic 5'-nucleotidase of human lymphoid cells.
    Johnson MA, Fridland A.
    Mol Pharmacol; 1989 Aug 04; 36(2):291-5. PubMed ID: 2549385
    [Abstract] [Full Text] [Related]

  • 16. Increased 5-phospho-alpha-D-ribose-1-diphosphate synthetase (ribosephosphate pyrophosphokinase, EC 2.7.6.1) activity in rat hepatomas.
    Baló-Banga JM, Weber G.
    Cancer Res; 1984 Nov 04; 44(11):5004-9. PubMed ID: 6091867
    [Abstract] [Full Text] [Related]

  • 17. Intracellular substrates for the primer-unblocking reaction by human immunodeficiency virus type 1 reverse transcriptase: detection and quantitation in extracts from quiescent- and activated-lymphocyte subpopulations.
    Smith AJ, Meyer PR, Asthana D, Ashman MR, Scott WA.
    Antimicrob Agents Chemother; 2005 May 04; 49(5):1761-9. PubMed ID: 15855493
    [Abstract] [Full Text] [Related]

  • 18. 5-Amino-4-imidazolecarboxamide riboside potentiates the metabolism and anti-human immunodeficiency virus activity of 2',3'-dideoxyinosine.
    Gong YF, Srinivas RV, Fridland A.
    Mol Pharmacol; 1993 Jul 04; 44(1):30-6. PubMed ID: 8341276
    [Abstract] [Full Text] [Related]

  • 19. Carbocyclic analogues of D-ribose-5-phosphate: synthesis and behavior with 5-phosphoribosyl alpha-1-pyrophosphate synthetases.
    Parry RJ, Burns MR, Skae PN, Hoyt JC, Pal B.
    Bioorg Med Chem; 1996 Jul 04; 4(7):1077-88. PubMed ID: 8831979
    [Abstract] [Full Text] [Related]

  • 20. Regulation of energy metabolism in macrophages during hypoxia. Roles of fructose 2,6-bisphosphate and ribose 1,5-bisphosphate.
    Kawaguchi T, Veech RL, Uyeda K.
    J Biol Chem; 2001 Jul 27; 276(30):28554-61. PubMed ID: 11373280
    [Abstract] [Full Text] [Related]

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