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438 related items for PubMed ID: 7949469

  • 1. Modulation of 1-[beta-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C.
    Grant S, Turner AJ, Bartimole TM, Nelms PA, Joe VC, Jarvis WD.
    Oncol Res; 1994; 6(2):87-99. PubMed ID: 7949469
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Grant S, Jarvis WD, Swerdlow PS, Turner AJ, Traylor RS, Wallace HJ, Lin PS, Pettit GR, Gewirtz DA.
    Cancer Res; 1992 Nov 15; 52(22):6270-8. PubMed ID: 1423273
    [Abstract] [Full Text] [Related]

  • 3. Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
    Grant S, Freemerman AJ, Birrer MJ, Martin HA, Turner AJ, Szabo E, Chelliah J, Jarvis WD.
    Cell Growth Differ; 1996 May 15; 7(5):603-13. PubMed ID: 8732670
    [Abstract] [Full Text] [Related]

  • 4. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
    Jarvis WD, Turner AJ, Povirk LF, Traylor RS, Grant S.
    Cancer Res; 1994 Apr 01; 54(7):1707-14. PubMed ID: 7511048
    [Abstract] [Full Text] [Related]

  • 5. Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells.
    Bullock G, Ray S, Reed J, Miyashita T, Maria Ibrado A, Huang Y, Bhalla K.
    Clin Cancer Res; 1995 May 01; 1(5):559-64. PubMed ID: 9816016
    [Abstract] [Full Text] [Related]

  • 6. Modulation of the expression of Bcl-2 and related proteins in human leukemia cells by protein kinase C activators: relationship to effects on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis.
    Bartimole TM, Vrana JA, Freemerman AJ, Jarvis WD, Reed JC, Boise LH, Grant S.
    Cell Death Differ; 1997 May 01; 4(4):294-303. PubMed ID: 16465244
    [Abstract] [Full Text] [Related]

  • 7. Induction of apoptotic DNA fragmentation and c-jun downregulation in human myeloid leukemia cells by the permeant Ca2+ chelator BAPTA/AM.
    Grant S, Freemerman AJ, Gregory PC, Martin HA, Turner AJ, Mikkelsen R, Chelliah J, Yanovich S, Jarvis WD.
    Oncol Res; 1995 May 01; 7(7-8):381-92. PubMed ID: 8747601
    [Abstract] [Full Text] [Related]

  • 8. Potentiation of the activity of nitric oxide by the protein kinase C activator phorbol ester in human myeloid leukemic HL-60 cells: association with enhanced fragmentation of mature genomic DNA.
    Jun CD, Park SJ, Choi BM, Kwak HJ, Park YC, Kim MS, Park RK, Chung HT.
    Cell Immunol; 1997 Feb 25; 176(1):41-9. PubMed ID: 9070316
    [Abstract] [Full Text] [Related]

  • 9. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis.
    Grant S, Turner AJ, Freemerman AJ, Wang Z, Kramer L, Jarvis WD.
    Exp Cell Res; 1996 Oct 10; 228(1):65-75. PubMed ID: 8892972
    [Abstract] [Full Text] [Related]

  • 10. Dysregulation of the cyclin-dependent kinase inhibitor p21WAF1/CIP1/MDA6 increases the susceptibility of human leukemia cells (U937) to 1-beta-D-arabinofuranosylcytosine-mediated mitochondrial dysfunction and apoptosis.
    Wang Z, Van Tuyle G, Conrad D, Fisher PB, Dent P, Grant S.
    Cancer Res; 1999 Mar 15; 59(6):1259-67. PubMed ID: 10096557
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of ribonucleotide reductase by a new class of isoindole derivatives: drug synergism with cytarabine (Ara-C) and induction of cellular apoptosis.
    Nandy P, Lien EJ, Avramis VI.
    Anticancer Res; 1999 Mar 15; 19(3A):1625-33. PubMed ID: 10470093
    [Abstract] [Full Text] [Related]

  • 12. Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
    Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S.
    Mol Pharmacol; 1997 Dec 15; 52(6):1000-9. PubMed ID: 9396780
    [Abstract] [Full Text] [Related]

  • 13. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells.
    Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S.
    Biochem Pharmacol; 1994 Mar 02; 47(5):839-52. PubMed ID: 8135859
    [Abstract] [Full Text] [Related]

  • 14. Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.
    Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S.
    Clin Cancer Res; 2001 Feb 02; 7(2):320-30. PubMed ID: 11234887
    [Abstract] [Full Text] [Related]

  • 15. Enforced expression of Bcl-XS induces differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-beta-D-arabinofuranosylcytosine-mediated differentiation and apoptosis.
    Ray S, Bullock G, Nuñez G, Tang C, Ibrado AM, Huang Y, Bhalla K.
    Cell Growth Differ; 1996 Dec 02; 7(12):1617-23. PubMed ID: 8959329
    [Abstract] [Full Text] [Related]

  • 16. 1-beta-D-arabinofuranosylcytosine activates serine/threonine protein kinases and c-jun gene expression in phorbol ester-resistant myeloid leukemia cells.
    Kharbanda S, Emoto Y, Kisaki H, Saleem A, Kufe D.
    Mol Pharmacol; 1994 Jul 02; 46(1):67-72. PubMed ID: 8058058
    [Abstract] [Full Text] [Related]

  • 17. The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells.
    Cartee L, Wang Z, Decker RH, Chellappan SP, Fusaro G, Hirsch KG, Sankala HM, Dent P, Grant S.
    Cancer Res; 2001 Mar 15; 61(6):2583-91. PubMed ID: 11289135
    [Abstract] [Full Text] [Related]

  • 18. Augmentation of 1-beta-D-arabinofuranosylcytosine cytotoxicity in human tumor cells by inhibiting drug efflux.
    Chan TC.
    Cancer Res; 1989 May 15; 49(10):2656-60. PubMed ID: 2713849
    [Abstract] [Full Text] [Related]

  • 19. Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds.
    Okazaki T, Kato Y, Mochizuki T, Tashima M, Sawada H, Uchino H.
    Exp Hematol; 1988 Jan 15; 16(1):42-8. PubMed ID: 2826200
    [Abstract] [Full Text] [Related]

  • 20. Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SY5Y human neuroblastoma cells through an alpha-, beta-, and zeta-protein kinase C-independent pathway.
    Jalava A, Akerman K, Heikkilä J.
    J Cell Physiol; 1993 May 15; 155(2):301-12. PubMed ID: 8482723
    [Abstract] [Full Text] [Related]

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