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468 related items for PubMed ID: 7958499

  • 1. Pancreatic expression and secretion of human islet amyloid polypeptide in a transgenic mouse.
    D'Alessio DA, Verchere CB, Kahn SE, Hoagland V, Baskin DG, Palmiter RD, Ensinck JW.
    Diabetes; 1994 Dec; 43(12):1457-61. PubMed ID: 7958499
    [Abstract] [Full Text] [Related]

  • 2. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
    Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.
    Diabetes; 2000 Dec; 49(12):2056-62. PubMed ID: 11118007
    [Abstract] [Full Text] [Related]

  • 3. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.
    Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905
    [Abstract] [Full Text] [Related]

  • 4. Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans.
    de Koning EJ, Höppener JW, Verbeek JS, Oosterwijk C, van Hulst KL, Baker CA, Lips CJ, Morris JF, Clark A.
    Diabetes; 1994 May 30; 43(5):640-4. PubMed ID: 8168639
    [Abstract] [Full Text] [Related]

  • 5. Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.
    Tokuyama T, Yagui K, Yamaguchi T, Huang CI, Kuramoto N, Shimada F, Miyazaki J, Horie H, Saito Y, Makino H, Kanatsuka A.
    Metabolism; 1997 Sep 30; 46(9):1044-51. PubMed ID: 9284894
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.
    Hull RL, Zraika S, Udayasankar J, Kisilevsky R, Szarek WA, Wight TN, Kahn SE.
    Am J Physiol Cell Physiol; 2007 Nov 30; 293(5):C1586-93. PubMed ID: 17804609
    [Abstract] [Full Text] [Related]

  • 7. Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
    Verchere CB, D'Alessio DA, Palmiter RD, Weir GC, Bonner-Weir S, Baskin DG, Kahn SE.
    Proc Natl Acad Sci U S A; 1996 Apr 16; 93(8):3492-6. PubMed ID: 8622964
    [Abstract] [Full Text] [Related]

  • 8. Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin.
    Yagui K, Yamaguchi T, Kanatsuka A, Shimada F, Huang CI, Tokuyama Y, Ohsawa H, Yamamura K, Miyazaki J, Mikata A.
    Eur J Endocrinol; 1995 Apr 16; 132(4):487-96. PubMed ID: 7711888
    [Abstract] [Full Text] [Related]

  • 9. Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
    Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.
    Diabetologia; 1999 Apr 16; 42(4):427-34. PubMed ID: 10230646
    [Abstract] [Full Text] [Related]

  • 10. Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
    Wong HY, Ahrén B, Lips CJ, Höppener JW, Sundler F.
    Regul Pept; 2003 May 15; 113(1-3):89-94. PubMed ID: 12686466
    [Abstract] [Full Text] [Related]

  • 11. Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
    Hull RL, Andrikopoulos S, Verchere CB, Vidal J, Wang F, Cnop M, Prigeon RL, Kahn SE.
    Diabetes; 2003 Feb 15; 52(2):372-9. PubMed ID: 12540610
    [Abstract] [Full Text] [Related]

  • 12. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J, Moreno-Vedia J, Obach M, Castaño C, de Pablo S, Alcarraz-Vizán G, Díaz-Catalán D, Mestre A, Horrillo R, Costa M, Novials A, Servitja JM.
    Mol Metab; 2020 Jul 15; 37():100984. PubMed ID: 32229246
    [Abstract] [Full Text] [Related]

  • 13. Effects of islet amyloid polypeptide (IAPP) on insulin biosynthesis or secretion in rat islets and mouse beta TC3 cells. Biosynthesis of IAPP in mouse beta TC3 cells.
    Nagamatsu S, Nishi M, Steiner DF.
    Diabetes Res Clin Pract; 1992 Jan 15; 15(1):49-55. PubMed ID: 1541235
    [Abstract] [Full Text] [Related]

  • 14. The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
    Verchere CB, D'Alessio DA, Prigeon RL, Hull RL, Kahn SE.
    Diabetes; 2000 Sep 15; 49(9):1477-84. PubMed ID: 10969831
    [Abstract] [Full Text] [Related]

  • 15. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY, Chehroudi CA, Denroche HC, Courtade JA, Ehses JA, Verchere CB.
    Diabetologia; 2015 Mar 15; 58(3):575-85. PubMed ID: 25491100
    [Abstract] [Full Text] [Related]

  • 16. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT, Entrup L, Templin AT, Hogan MF, Mellati M, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2016 Oct 15; 59(10):2166-71. PubMed ID: 27393137
    [Abstract] [Full Text] [Related]

  • 17. Elevated islet amyloid pancreatic polypeptide and proinsulin in lean gestational diabetes.
    Kautzky-Willer A, Thomaseth K, Ludvik B, Nowotny P, Rabensteiner D, Waldhäusl W, Pacini G, Prager R.
    Diabetes; 1997 Apr 15; 46(4):607-14. PubMed ID: 9075800
    [Abstract] [Full Text] [Related]

  • 18. An in vitro model of early islet amyloid polypeptide (IAPP) fibrillogenesis using human IAPP-transgenic mouse islets.
    Henson MS, Buman BL, Jordan K, Rahrmann EP, Hardy RM, Johnson KH, O'Brien TD.
    Amyloid; 2006 Dec 15; 13(4):250-9. PubMed ID: 17107885
    [Abstract] [Full Text] [Related]

  • 19. The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
    Vidal J, Verchere CB, Andrikopoulos S, Wang F, Hull RL, Cnop M, Olin KL, LeBoeuf RC, O'Brien KD, Chait A, Kahn SE.
    Diabetologia; 2003 Jan 15; 46(1):71-9. PubMed ID: 12637985
    [Abstract] [Full Text] [Related]

  • 20. Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
    Jaikaran ET, Clark A.
    Biochim Biophys Acta; 2001 Nov 29; 1537(3):179-203. PubMed ID: 11731221
    [Abstract] [Full Text] [Related]

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