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Journal Abstract Search

778 related items for PubMed ID: 7969089

  • 1. Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.
    Hawkinson JE, Kimbrough CL, Belelli D, Lambert JJ, Purdy RH, Lan NC.
    Mol Pharmacol; 1994 Nov; 46(5):977-85. PubMed ID: 7969089
    [Abstract] [Full Text] [Related]

  • 2. 3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor.
    Hawkinson JE, Drewe JA, Kimbrough CL, Chen JS, Hogenkamp DJ, Lan NC, Gee KW, Shen KZ, Whittemore ER, Woodward RM.
    Mol Pharmacol; 1996 May; 49(5):897-906. PubMed ID: 8622640
    [Abstract] [Full Text] [Related]

  • 3. Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
    Hawkinson JE, Acosta-Burruel M, Yang KC, Hogenkamp DJ, Chen JS, Lan NC, Drewe JA, Whittemore ER, Woodward RM, Carter RB, Upasani RB.
    J Pharmacol Exp Ther; 1998 Oct; 287(1):198-207. PubMed ID: 9765338
    [Abstract] [Full Text] [Related]

  • 4. Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.
    Gee KW, Bolger MB, Brinton RE, Coirini H, McEwen BS.
    J Pharmacol Exp Ther; 1988 Aug; 246(2):803-12. PubMed ID: 2841455
    [Abstract] [Full Text] [Related]

  • 5. Selective actions of certain neuroactive pregnanediols at the gamma-aminobutyric acid type A receptor complex in rat brain.
    McCauley LD, Liu V, Chen JS, Hawkinson JE, Lan NC, Gee KW.
    Mol Pharmacol; 1995 Feb; 47(2):354-62. PubMed ID: 7870044
    [Abstract] [Full Text] [Related]

  • 6. Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes.
    Pregenzer JF, Im WB, Carter DB, Thomsen DR.
    Mol Pharmacol; 1993 May; 43(5):801-6. PubMed ID: 8388991
    [Abstract] [Full Text] [Related]

  • 7. Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
    Harrison NL, Majewska MD, Harrington JW, Barker JL.
    J Pharmacol Exp Ther; 1987 Apr; 241(1):346-53. PubMed ID: 3033209
    [Abstract] [Full Text] [Related]

  • 8. Correlation between gamma-aminobutyric acidA receptor ligand-induced changes in t-butylbicyclophosphoro[35S]thionate binding and 36Cl- uptake in rat cerebrocortical membranes.
    Im WB, Blakeman DP.
    Mol Pharmacol; 1991 Mar; 39(3):394-8. PubMed ID: 1848661
    [Abstract] [Full Text] [Related]

  • 9. Loreclezole modulates [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding via a distinct site on the GABAA receptor complex.
    Xue BG, Friend JM, Gee KW.
    Eur J Pharmacol; 1996 Apr 04; 300(1-2):125-30. PubMed ID: 8741177
    [Abstract] [Full Text] [Related]

  • 10. Regional gamma-aminobutyric acid sensitivity of t-butylbicyclophosphoro[35S]thionate binding depends on gamma-aminobutyric acidA receptor alpha subunit.
    Korpi ER, Lüddens H.
    Mol Pharmacol; 1993 Jul 04; 44(1):87-92. PubMed ID: 8393526
    [Abstract] [Full Text] [Related]

  • 11. Influence of the estrus cycle on the discrimination of apparent neuroactive steroid site subtypes on the gamma-aminobutyric acidA receptor complex in the rat.
    McCauley LD, Gee KW.
    J Pharmacol Exp Ther; 1995 Dec 04; 275(3):1412-7. PubMed ID: 8531110
    [Abstract] [Full Text] [Related]

  • 12. Steroid modulation of GABAA receptors in an amphibian brain.
    Orchinik M, Murray TF, Moore FL.
    Brain Res; 1994 May 23; 646(2):258-66. PubMed ID: 8069672
    [Abstract] [Full Text] [Related]

  • 13. Radiation inactivation of brain [35S]t-butylbicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.
    Nielsen M, Honore T, Braestrup C.
    Biochem Pharmacol; 1985 Oct 15; 34(20):3633-42. PubMed ID: 2413862
    [Abstract] [Full Text] [Related]

  • 14. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.
    Carter RB, Wood PL, Wieland S, Hawkinson JE, Belelli D, Lambert JJ, White HS, Wolf HH, Mirsadeghi S, Tahir SH, Bolger MB, Lan NC, Gee KW.
    J Pharmacol Exp Ther; 1997 Mar 15; 280(3):1284-95. PubMed ID: 9067315
    [Abstract] [Full Text] [Related]

  • 15. Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.
    Turner DM, Ransom RW, Yang JS, Olsen RW.
    J Pharmacol Exp Ther; 1989 Mar 15; 248(3):960-6. PubMed ID: 2539464
    [Abstract] [Full Text] [Related]

  • 16. 3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
    Giusti L, Belfiore MS, Martini C, Lucacchini A.
    J Steroid Biochem Mol Biol; 1993 Apr 15; 45(4):309-14. PubMed ID: 8388709
    [Abstract] [Full Text] [Related]

  • 17. The activity of zolpidem and other hypnotics within the gamma-aminobutyric acid (GABAA) receptor supramolecular complex, as determined by 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding to rat cerebral cortex membranes.
    Lloyd GK, Danielou G, Thuret F.
    J Pharmacol Exp Ther; 1990 Nov 15; 255(2):690-6. PubMed ID: 2173755
    [Abstract] [Full Text] [Related]

  • 18. Effects of pentobarbital on t-[35S]butylbicyclophosphorothionate and [3H]flunitrazepam binding to membrane-bound and solubilized preparations from rat forebrain.
    Richter JA, Yamamura HI.
    J Pharmacol Exp Ther; 1985 Apr 15; 233(1):125-33. PubMed ID: 2984410
    [Abstract] [Full Text] [Related]

  • 19. Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
    Corda MG, Longoni B, Cau A, Paci S, Salvadori S, Laudani U, Biggio G.
    J Neurochem; 1989 Apr 15; 52(4):1025-34. PubMed ID: 2538558
    [Abstract] [Full Text] [Related]

  • 20. The neuroactive steroid 3 alpha-hydroxy-5 beta-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor.
    Hawkinson JE, Kimbrough CL, McCauley LD, Bolger MB, Lan NC, Gee KW.
    Eur J Pharmacol; 1994 Oct 14; 269(2):157-63. PubMed ID: 7851492
    [Abstract] [Full Text] [Related]

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