These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

150 related items for PubMed ID: 7981057

  • 21. Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2647-54. PubMed ID: 1385949
    [Abstract] [Full Text] [Related]

  • 22. Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
    Grem JL, Allegra CJ.
    Biochem Pharmacol; 1991 Jul 05; 42(2):409-18. PubMed ID: 1713459
    [Abstract] [Full Text] [Related]

  • 23. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells.
    Rhee MS, Balinska M, Bunni M, Priest DG, Maley GF, Maley F, Galivan J.
    Cancer Res; 1990 Jul 01; 50(13):3979-84. PubMed ID: 2162250
    [Abstract] [Full Text] [Related]

  • 24. Characterization of trimetrexate transport in human lymphoblastoid cells and development of impaired influx as a mechanism of resistance to lipophilic antifolates.
    Fry DW, Besserer JA.
    Cancer Res; 1988 Dec 15; 48(24 Pt 1):6986-91. PubMed ID: 2973370
    [Abstract] [Full Text] [Related]

  • 25. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues.
    Miyachi H, Takemura Y, Kobayashi H, Ando K, Ando Y.
    Jpn J Cancer Res; 1993 Jan 15; 84(1):9-12. PubMed ID: 8449831
    [Abstract] [Full Text] [Related]

  • 26. Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations.
    Piper JR, Johnson CA, Krauth CA, Carter RL, Hosmer CA, Queener SF, Borotz SE, Pfefferkorn ER.
    J Med Chem; 1996 Mar 15; 39(6):1271-80. PubMed ID: 8632434
    [Abstract] [Full Text] [Related]

  • 27. Lipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease.
    Senkovich O, Bhatia V, Garg N, Chattopadhyay D.
    Antimicrob Agents Chemother; 2005 Aug 15; 49(8):3234-8. PubMed ID: 16048931
    [Abstract] [Full Text] [Related]

  • 28. Dihydrofolate reductase as a target for chemotherapy in parasites.
    Gangjee A, Kurup S, Namjoshi O.
    Curr Pharm Des; 2007 Aug 15; 13(6):609-39. PubMed ID: 17346178
    [Abstract] [Full Text] [Related]

  • 29. New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.
    Zhang Q, Nguyen T, McMichael M, Velu SE, Zou J, Zhou X, Wu H.
    Int J Antimicrob Agents; 2015 Aug 15; 46(2):174-82. PubMed ID: 26022931
    [Abstract] [Full Text] [Related]

  • 30. Modulation of fluorouracil cytotoxicity by interferon-alpha and -gamma.
    Ismail A, Van Groeningen CJ, Hardcastle A, Ren Q, Aherne GW, Geoffroy F, Allegra CJ, Grem JL.
    Mol Pharmacol; 1998 Feb 15; 53(2):252-61. PubMed ID: 9463483
    [Abstract] [Full Text] [Related]

  • 31. Mechanism of the induction of the differentiation of HL-60 leukemia cells by antifolates.
    Sokoloski JA, Beardsley GP, Sartorelli AC.
    Cancer Commun; 1989 Feb 15; 1(3):199-207. PubMed ID: 2700913
    [Abstract] [Full Text] [Related]

  • 32. Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
    Antosiewicz A, Jarmuła A, Przybylska D, Mosieniak G, Szczepanowska J, Kowalkowska A, Rode W, Cieśla J.
    J Biomol Struct Dyn; 2017 May 15; 35(7):1474-1490. PubMed ID: 27187663
    [Abstract] [Full Text] [Related]

  • 33. Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells: elevated dTTP pools and enhanced cytotoxicity.
    Mullany S, Svingen PA, Kaufmann SH, Erlichman C.
    Cancer Chemother Pharmacol; 1998 May 15; 42(5):391-9. PubMed ID: 9771954
    [Abstract] [Full Text] [Related]

  • 34. Implications for improved high-dose methotrexate therapeutic effects in cultured human breast cancer and bone marrow cells.
    Bowen D, Southerland WM, Johnson DH, Hawkins M, Hughes DE.
    Cancer Detect Prev; 2000 May 15; 24(5):452-8. PubMed ID: 11129987
    [Abstract] [Full Text] [Related]

  • 35. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
    Mayer-Kuckuk P, Banerjee D, Malhotra S, Doubrovin M, Iwamoto M, Akhurst T, Balatoni J, Bornmann W, Finn R, Larson S, Fong Y, Gelovani Tjuvajev J, Blasberg R, Bertino JR.
    Proc Natl Acad Sci U S A; 2002 Mar 19; 99(6):3400-5. PubMed ID: 11891321
    [Abstract] [Full Text] [Related]

  • 36. A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    FitzGerald GB, Wick MM.
    Anticancer Drug Des; 1989 Jun 19; 4(1):79-87. PubMed ID: 2757754
    [Abstract] [Full Text] [Related]

  • 37. Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
    Curtin NJ, Harris AL, Aherne GW.
    Cancer Res; 1991 May 01; 51(9):2346-52. PubMed ID: 2015598
    [Abstract] [Full Text] [Related]

  • 38. Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: the critical role of polyglutamylation.
    Faessel HM, Slocum HK, Jackson RC, Boritzki TJ, Rustum YM, Nair MG, Greco WR.
    Cancer Res; 1998 Jul 15; 58(14):3036-50. PubMed ID: 9679969
    [Abstract] [Full Text] [Related]

  • 39. Selectivity in human breast cancer and human bone marrow using trimetrexate in combination with 5-fluorouracil.
    Bowen D, Johnson DH, Southerland WM, Hughes DE, Hawkins M.
    Anticancer Res; 1999 Jul 15; 19(5B):3837-40. PubMed ID: 10628320
    [Abstract] [Full Text] [Related]

  • 40. A randomized trial of two schedules of trimetrexate versus 5-fluorouracil in advanced colorectal cancer: a Southwest Oncology Group study.
    Brown TD, Fleming TR, Goodman PJ, Macdonald JS, Pugh RP, O'Rourke T.
    Anticancer Drugs; 1995 Apr 15; 6(2):219-23. PubMed ID: 7795270
    [Abstract] [Full Text] [Related]

    Page: [Previous] [Next] [New Search]
    of 8.