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89 related items for PubMed ID: 7986254

  • 1. Effects of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6yl-hydrogen phosphate] potassium salt on cerebral energy state and consciousness recovery following transient forebrain ischemia in gerbils.
    Kuribayashi Y, Naritomi H, Sasaki M, Sawada T.
    Arzneimittelforschung; 1994 Sep; 44(9):995-8. PubMed ID: 7986254
    [Abstract] [Full Text] [Related]

  • 2. Effect of bifemelane on the intracellular pH and energy state of the ischemic brain.
    Naritomi H, Sasaki M, Maruki Y, Izuta M, Kanashiro M, Sawada T.
    Arzneimittelforschung; 1990 Sep; 40(9):965-8. PubMed ID: 2127887
    [Abstract] [Full Text] [Related]

  • 3. In vitro studies on the influence of L-ascorbic acid 2-[3,4-dihydro- 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6yl-hy drogen phosphate] potassium salt on lipid peroxidation and phospholipase A2 activity.
    Kuribayashi Y, Yoshida K, Sakaue T, Okumura A.
    Arzneimittelforschung; 1992 Sep; 42(9):1072-4. PubMed ID: 1445471
    [Abstract] [Full Text] [Related]

  • 4. Effects of propentofylline on energy metabolism of the ischemic brain studied by in vivo 31P nuclear magnetic resonance spectroscopy.
    Sasaki M, Naritomi H, Kanashiro M, Nishimura H, Sawada T.
    Arzneimittelforschung; 1989 Aug; 39(8):886-9. PubMed ID: 2510744
    [Abstract] [Full Text] [Related]

  • 5. Attenuation of oxidative DNA damage with a novel antioxidant EPC-K1 in rat brain neuronal cells after transient middle cerebral artery occlusion.
    Zhang WR, Hayashi T, Sasaki C, Sato K, Nagano I, Manabe Y, Abe K.
    Neurol Res; 2001 Sep; 23(6):676-80. PubMed ID: 11547942
    [Abstract] [Full Text] [Related]

  • 6. The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia.
    Kato N, Yanaka K, Nagase S, Hirayama A, Nose T.
    Acta Neurochir (Wien); 2003 Jun; 145(6):489-93; discussion 493. PubMed ID: 12836074
    [Abstract] [Full Text] [Related]

  • 7. Restoration of the glucocorticoid receptor function by the phosphodiester compound of vitamins C and E, EPC-K1 (L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl hydrogen phosphate] potassium salt), via a redox-dependent mechanism.
    Okamoto K, Tanaka H, Makino Y, Makino I.
    Biochem Pharmacol; 1998 Jul 01; 56(1):79-86. PubMed ID: 9698091
    [Abstract] [Full Text] [Related]

  • 8. Duration threshold of induced hypertension on cerebral blood flow, energy metabolism, and edema after transient forebrain ischemia in gerbils.
    Hosomi N, Tsuda Y, Ichihara SI, Kitadai M, Ohyama H, Matsuo H.
    J Cereb Blood Flow Metab; 1996 Nov 01; 16(6):1224-9. PubMed ID: 8898695
    [Abstract] [Full Text] [Related]

  • 9. Reduced ischemia-reperfusion injury in muscle. Experiments in rats with EPC-K1, a new radical scavenger.
    Hirose J, Yamaga M, Ide J, Tanoue M, Takagi K.
    Acta Orthop Scand; 1997 Aug 01; 68(4):369-73. PubMed ID: 9310042
    [Abstract] [Full Text] [Related]

  • 10. [Effect of phosphate diester linkage of vitamin E and vitamin C (EPC-K1) on myocardial ischemia reperfusion injury in the isolated working rat heart].
    Inoue M.
    Nihon Kyobu Geka Gakkai Zasshi; 1997 May 01; 45(5):742-9. PubMed ID: 9170867
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory effects of a phosphate diester of alpha-tocopherol and ascorbic acid (EPC-K1) on myocardial infarction in rats.
    Kuribayashi Y, Katori M, Majima M, Yoshida K.
    Int J Tissue React; 1996 May 01; 18(2-3):73-9. PubMed ID: 9063769
    [Abstract] [Full Text] [Related]

  • 12. Hydroxyl radical generation after the third hour following ischemia contributes to brain damage.
    Takamatsu H, Kondo K, Ikeda Y, Umemura K.
    Eur J Pharmacol; 1998 Jul 10; 352(2-3):165-9. PubMed ID: 9716351
    [Abstract] [Full Text] [Related]

  • 13. EPC-K1 is effective in lung preservation in an ex vivo rabbit lung perfusion model.
    Nagahiro I, Aoe M, Yamashita M, Date H, Andou A, Shimizu N.
    Ann Thorac Surg; 1997 Apr 10; 63(4):954-9. PubMed ID: 9124970
    [Abstract] [Full Text] [Related]

  • 14. Dentin is dissolved by high concentrations of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl-hydrogen phosphate] potassium salt with or without hydrogen peroxide.
    Kozuka M, Tsujimoto Y.
    Biol Pharm Bull; 2004 Jun 10; 27(6):831-4. PubMed ID: 15187428
    [Abstract] [Full Text] [Related]

  • 15. Characterization of the activity of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-be nzopyran-6-yl-hydrogen phosphate] potassium salt in hydroxyl radical elimination.
    Tomita T, Kashima M, Tsujimoto Y.
    Chem Pharm Bull (Tokyo); 2000 Mar 10; 48(3):330-3. PubMed ID: 10726851
    [Abstract] [Full Text] [Related]

  • 16. Effects of mannitol and glycerol on cerebral energy metabolism in gerbils.
    Tsuda Y, Kitadai M, Hatanaka Y, Izumi Y.
    Acta Neurol Scand; 1998 Jul 10; 98(1):36-40. PubMed ID: 9696525
    [Abstract] [Full Text] [Related]

  • 17. Relation of postischemic delayed hypoperfusion and cerebral edema after transient forebrain ischemia.
    Hosomi N, Ohyama H, Ichihara S, Takahashi T, Naya T, Kohno M.
    J Stroke Cerebrovasc Dis; 2007 Jul 10; 16(3):103-8. PubMed ID: 17689403
    [Abstract] [Full Text] [Related]

  • 18. Antioxidant properties of EPC-K1: a study on mechanisms.
    Wei T, Chen C, Li F, Zhao B, Hou J, Xin W, Mori A.
    Biophys Chem; 1999 Mar 29; 77(2-3):153-60. PubMed ID: 10326248
    [Abstract] [Full Text] [Related]

  • 19. Effects of a hydroxyl radical scavenger, EPC-K1, and neutrophil depletion on reperfusion injury in rat skeletal muscle.
    Hirose J, Yamaga M, Kato T, Ikebe K, Takagi K.
    Acta Orthop Scand; 2001 Aug 29; 72(4):404-10. PubMed ID: 11580130
    [Abstract] [Full Text] [Related]

  • 20. Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils.
    Cao D, Li M, Xue R, Zheng W, Liu Z, Wang X.
    Life Sci; 2005 Nov 19; 78(1):74-81. PubMed ID: 16214179
    [Abstract] [Full Text] [Related]

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