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Journal Abstract Search

217 related items for PubMed ID: 7987823

  • 1. Kinetics of the in vivo interconversion of the carboxylate and lactone forms of irinotecan (CPT-11) and of its metabolite SN-38 in patients.
    Rivory LP, Chatelut E, Canal P, Mathieu-Boué A, Robert J.
    Cancer Res; 1994 Dec 15; 54(24):6330-3. PubMed ID: 7987823
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  • 2. Clinical pharmacokinetics of irinotecan and its metabolites: a population analysis.
    Xie R, Mathijssen RH, Sparreboom A, Verweij J, Karlsson MO.
    J Clin Oncol; 2002 Aug 01; 20(15):3293-301. PubMed ID: 12149304
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  • 4. Pharmacological correlation between total drug concentration and lactones of CPT-11 and SN-38 in patients treated with CPT-11.
    Sasaki Y, Yoshida Y, Sudoh K, Hakusui H, Fujii H, Ohtsu T, Wakita H, Igarashi T, Itoh K.
    Jpn J Cancer Res; 1995 Jan 01; 86(1):111-6. PubMed ID: 7737902
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  • 6. The transformation of irinotecan (CPT-11) to its active metabolite SN-38 by human liver microsomes. Differential hydrolysis for the lactone and carboxylate forms.
    Haaz MC, Rivory LP, Riché C, Robert J.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Aug 01; 356(2):257-62. PubMed ID: 9272733
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  • 7. 20-O-acylcamptothecin derivatives: evidence for lactone stabilization.
    Zhao H, Lee C, Sai P, Choe YH, Boro M, Pendri A, Guan S, Greenwald RB.
    J Org Chem; 2000 Jul 28; 65(15):4601-6. PubMed ID: 10959865
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  • 10. Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in the rat.
    Yang X, Hu Z, Chan SY, Goh BC, Duan W, Chan E, Zhou S.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2005 Jul 25; 821(2):221-8. PubMed ID: 15936253
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  • 13. Determination of irinotecan and its metabolite SN-38 in rabbit plasma and tumors using a validated method of tandem mass spectrometry coupled with liquid chromatography.
    Park DJ, Won JH, Cho AR, Yun HJ, Heo JH, Hwhang TH, Lee DH, Kim WM.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Jul 01; 962():147-152. PubMed ID: 24927278
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  • 18. Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates.
    Blaney SM, Takimoto C, Murry DJ, Kuttesch N, McCully C, Cole DE, Godwin K, Balis FM.
    Cancer Chemother Pharmacol; 1998 Jul 01; 41(6):464-8. PubMed ID: 9554590
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  • 19. Identification of a new metabolite of CPT-11 (irinotecan): pharmacological properties and activation to SN-38.
    Dodds HM, Haaz MC, Riou JF, Robert J, Rivory LP.
    J Pharmacol Exp Ther; 1998 Jul 01; 286(1):578-83. PubMed ID: 9655905
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  • 20. Kinetics of lactone hydrolysis in antitumor drugs of camptothecin series as studied by fluorescence spectroscopy.
    Chourpa I, Millot JM, Sockalingum GD, Riou JF, Manfait M.
    Biochim Biophys Acta; 1998 Mar 02; 1379(3):353-66. PubMed ID: 9545598
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