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232 related items for PubMed ID: 7991583
41. Expression and purification of recombinant immunotoxin--a fusion protein stabilizes a single-chain Fv (scFv) in denaturing condition. Kim SH. Protein Expr Purif; 2003 Jan; 27(1):85-9. PubMed ID: 12509988 [Abstract] [Full Text] [Related]
42. In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma. Onda M, Wang QC, Guo HF, Cheung NK, Pastan I. Cancer Res; 2004 Feb 15; 64(4):1419-24. PubMed ID: 14973056 [Abstract] [Full Text] [Related]
43. Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments. Nagata S, Onda M, Numata Y, Santora K, Beers R, Kreitman RJ, Pastan I. Clin Cancer Res; 2002 Jul 15; 8(7):2345-55. PubMed ID: 12114439 [Abstract] [Full Text] [Related]
44. New immunotoxins targeting CD123, a stem cell antigen on acute myeloid leukemia cells. Du X, Ho M, Pastan I. J Immunother; 2007 Sep 15; 30(6):607-13. PubMed ID: 17667524 [Abstract] [Full Text] [Related]
45. A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies. Buchner J, Pastan I, Brinkmann U. Anal Biochem; 1992 Sep 15; 205(2):263-70. PubMed ID: 1332541 [Abstract] [Full Text] [Related]
46. Reduction of the nonspecific animal toxicity of anti-Tac(Fv)-PE38 by mutations in the framework regions of the Fv which lower the isoelectric point. Onda M, Kreitman RJ, Vasmatzis G, Lee B, Pastan I. J Immunol; 1999 Dec 01; 163(11):6072-7. PubMed ID: 10570296 [Abstract] [Full Text] [Related]
47. A variant of exotoxin A that forms potent and specific chemically conjugated immunotoxins. Chaudry GJ, Fulton RJ, Draper RK. J Biol Chem; 1993 May 05; 268(13):9437-41. PubMed ID: 8486636 [Abstract] [Full Text] [Related]
48. Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin. Pai LH, Batra JK, FitzGerald DJ, Willingham MC, Pastan I. Proc Natl Acad Sci U S A; 1991 Apr 15; 88(8):3358-62. PubMed ID: 2014255 [Abstract] [Full Text] [Related]
49. Antitumor activity and pharmacokinetics in mice of a recombinant immunotoxin containing a disulfide-stabilized Fv fragment. Reiter Y, Pai LH, Brinkmann U, Wang QC, Pastan I. Cancer Res; 1994 May 15; 54(10):2714-8. PubMed ID: 8168102 [Abstract] [Full Text] [Related]
50. In vitro and in vivo efficacy of a recombinant immunotoxin against folate receptor beta on the activation and proliferation of rheumatoid arthritis synovial cells. Nagai T, Tanaka M, Tsuneyoshi Y, Matsushita K, Sunahara N, Matsuda T, Yoshida H, Komiya S, Onda M, Matsuyama T. Arthritis Rheum; 2006 Oct 15; 54(10):3126-34. PubMed ID: 17009233 [Abstract] [Full Text] [Related]
52. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv). Batra JK, Fitzgerald DJ, Chaudhary VK, Pastan I. Mol Cell Biol; 1991 Apr 15; 11(4):2200-5. PubMed ID: 2005905 [Abstract] [Full Text] [Related]
53. Enhanced formation of disulfide-bridged dimer (Fab-PE38)2 utilizing repeats of the Fab binding domain of protein G. Lee Y, Park J, Kweon S, Choe M. J Biol Chem; 2010 Feb 19; 285(8):5127-31. PubMed ID: 20022943 [Abstract] [Full Text] [Related]
54. Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor. Kreitman RJ, Pastan I. Biochem J; 1995 Apr 01; 307 ( Pt 1)(Pt 1):29-37. PubMed ID: 7717988 [Abstract] [Full Text] [Related]
57. Comparison of recombinant immunotoxins against LeY antigen expressing tumor cells: influence of affinity, size, and stability. Bera TK, Pastan I. Bioconjug Chem; 1998 Apr 01; 9(6):736-43. PubMed ID: 9815167 [Abstract] [Full Text] [Related]
58. Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A. Kaplan G, Lee F, Onda M, Kolyvas E, Bhardwaj G, Baker D, Pastan I. Toxins (Basel); 2016 Jul 25; 8(8):. PubMed ID: 27463727 [Abstract] [Full Text] [Related]
59. Application of 13C NMR spectroscopy to paratope mapping for larger antigen-Fab complexes. Kim H, Kato K, Yamato S, Igarashi T, Matsunaga C, Ohtsuka H, Higuchi A, Nomura N, Noguchi H, Arata Y. FEBS Lett; 1994 Jun 13; 346(2-3):246-50. PubMed ID: 8013642 [Abstract] [Full Text] [Related]