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Journal Abstract Search

240 related items for PubMed ID: 7996550

  • 1. Development of a model for the delta opioid receptor pharmacophore. 2. Conformationally restricted Phe3 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).
    Mosberg HI, Omnaas JR, Lomize A, Heyl DL, Nordan I, Mousigian C, Davis P, Porreca F.
    J Med Chem; 1994 Dec 09; 37(25):4384-91. PubMed ID: 7996550
    [Abstract] [Full Text] [Related]

  • 2. Development of a model for the delta opioid receptor pharmacophore. 1. Conformationally restricted Tyr1 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).
    Mosberg HI, Lomize AL, Wang C, Kroona H, Heyl DL, Sobczyk-Kojiro K, Ma W, Mousigian C, Porreca F.
    J Med Chem; 1994 Dec 09; 37(25):4371-83. PubMed ID: 7996549
    [Abstract] [Full Text] [Related]

  • 3. Development of a model for the delta-opioid receptor pharmacophore. 4. Residue 3 dehydrophenylalanine analogues of Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13) confirm required gauche orientation of aromatic side chain.
    Mosberg HI, Dua RK, Pogozheva ID, Lomize AL.
    Biopolymers; 1996 Sep 09; 39(3):287-96. PubMed ID: 8756510
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  • 4. Synthesis and biological properties of beta-MePhe3 analogues of deltorphin I and dermenkephalin: influence of biased chi 1 Phe3 residues on peptide recognition for delta-opioid receptors.
    Misicka A, Cavagnero S, Horvath R, Davis P, Porreca F, Yamamura HI, Hruby VJ.
    J Pept Res; 1997 Jul 09; 50(1):48-54. PubMed ID: 9273887
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  • 5. Phe3-substituted analogues of deltorphin C. Spatial conformation and topography of the aromatic ring in peptide recognition by delta opioid receptors.
    Salvadori S, Bryant SD, Bianchi C, Balboni G, Scaranari V, Attila M, Lazarus LH.
    J Med Chem; 1993 Nov 26; 36(24):3748-56. PubMed ID: 8254604
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  • 7. Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analogue: effects on receptor selectivity and stereospecificity.
    Schiller PW, Weltrowska G, Nguyen TM, Lemieux C, Chung NN, Marsden BJ, Wilkes BC.
    J Med Chem; 1991 Oct 26; 34(10):3125-32. PubMed ID: 1656045
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  • 8. Side chain methyl substitution in the delta-opioid receptor antagonist TIPP has an important effect on the activity profile.
    Tourwé D, Mannekens E, Diem TN, Verheyden P, Jaspers H, Tóth G, Péter A, Kertész I, Török G, Chung NN, Schiller PW.
    J Med Chem; 1998 Dec 17; 41(26):5167-76. PubMed ID: 9857087
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  • 9. Development of a model for the delta-opioid receptor pharmacophore: 3. Comparison of the cyclic tetrapeptide, Tyr-c[D-Cys-Phe-D-Pen]OH with other conformationally constrained delta-receptor selective ligands.
    Lomize AL, Pogozheva ID, Mosberg HI.
    Biopolymers; 1996 Feb 17; 38(2):221-34. PubMed ID: 8589255
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  • 11. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
    Bonner GG, Davis P, Stropova D, Edsall S, Yamamura HI, Porreca F, Hruby VJ.
    J Med Chem; 2000 Feb 24; 43(4):569-80. PubMed ID: 10691683
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  • 12. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
    Salvadori S, Balboni G, Guerrini R, Tomatis R, Bianchi C, Bryant SD, Cooper PS, Lazarus LH.
    J Med Chem; 1997 Sep 12; 40(19):3100-8. PubMed ID: 9301674
    [Abstract] [Full Text] [Related]

  • 13. Conformationally restricted deltorphin analogues.
    Schiller PW, Weltrowska G, Nguyen TM, Wilkes BC, Chung NN, Lemieux C.
    J Med Chem; 1992 Oct 16; 35(21):3956-61. PubMed ID: 1331451
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  • 15. Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.
    Schiller PW, Nguyen TM, Weltrowska G, Wilkes BC, Marsden BJ, Lemieux C, Chung NN.
    Proc Natl Acad Sci U S A; 1992 Dec 15; 89(24):11871-5. PubMed ID: 1334552
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  • 16. Synthesis and activity profiles of novel cyclic opioid peptide monomers and dimers.
    Schiller PW, Nguyen TM, Lemieux C, Maziak LA.
    J Med Chem; 1985 Dec 15; 28(12):1766-71. PubMed ID: 2999401
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  • 19. Cyclic, disulfide- and dithioether-containing opioid tetrapeptides: development of a ligand with high delta opioid receptor selectivity and affinity.
    Mosberg HI, Omnaas JR, Medzihradsky F, Smith CB.
    Life Sci; 1988 Dec 15; 43(12):1013-20. PubMed ID: 2845204
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