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240 related items for PubMed ID: 7996550

  • 21. Synthesis and biological activities of cyclic lanthionine enkephalin analogues: delta-opioid receptor selective ligands.
    Rew Y, Malkmus S, Svensson C, Yaksh TL, Chung NN, Schiller PW, Cassel JA, DeHaven RN, Taulane JP, Goodman M.
    J Med Chem; 2002 Aug 15; 45(17):3746-54. PubMed ID: 12166947
    [Abstract] [Full Text] [Related]

  • 22. Comparison of mu-, delta- and kappa-receptor binding sites through pharmacologic evaluation of p-nitrophenylalanine analogs of opioid peptides.
    Schiller PW, Nguyen TM, DiMaio J, Lemieux C.
    Life Sci; 1983 Aug 15; 33 Suppl 1():319-22. PubMed ID: 6319885
    [Abstract] [Full Text] [Related]

  • 23. Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin.
    Witt KA, Slate CA, Egleton RD, Huber JD, Yamamura HI, Hruby VJ, Davis TP.
    J Neurochem; 2000 Jul 15; 75(1):424-35. PubMed ID: 10854288
    [Abstract] [Full Text] [Related]

  • 24. De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
    Liao S, Alfaro-Lopez J, Shenderovich MD, Hosohata K, Lin J, Li X, Stropova D, Davis P, Jernigan KA, Porreca F, Yamamura HI, Hruby VJ.
    J Med Chem; 1998 Nov 19; 41(24):4767-76. PubMed ID: 9822547
    [Abstract] [Full Text] [Related]

  • 25. Opioid receptor affinity and selectivity effects of second residue and carboxy terminal residue variation in a cyclic disulfide-containing opioid tetrapeptide.
    Heyl DL, Omnaas JR, Sobczyk-Kojiro K, Medzihradsky F, Smith CB, Mosberg HI.
    Int J Pept Protein Res; 1991 Mar 19; 37(3):224-9. PubMed ID: 1651290
    [Abstract] [Full Text] [Related]

  • 26. Cyclic dermorphin-like tetrapeptides with delta-opioid receptor selectivity. 3. Effect of residue 3 modification on in vitro opioid activity.
    Mosberg HI, Heyl DL, Haaseth RC, Omnaas JR, Medzihradsky F, Smith CB.
    Mol Pharmacol; 1990 Dec 19; 38(6):924-8. PubMed ID: 2174509
    [Abstract] [Full Text] [Related]

  • 27. Cyclic enkephalin analogs containing various para-substituted phenylalanine derivatives in place of Tyr1 are potent opioid agonists.
    Weltrowska G, Lemieux C, Chung NN, Schiller PW.
    J Pept Res; 2005 Jan 19; 65(1):36-41. PubMed ID: 15686532
    [Abstract] [Full Text] [Related]

  • 28. Development and validation of opioid ligand-receptor interaction models: the structural basis of mu vs delta selectivity.
    Mosberg HI, Fowler CB.
    J Pept Res; 2002 Dec 19; 60(6):329-35. PubMed ID: 12464111
    [Abstract] [Full Text] [Related]

  • 29. Opioid profiles of Cys2-containing enkephalin analogues.
    Pencheva N, Milanov P, Vezenkov L, Pajpanova T, Naydenova E.
    Eur J Pharmacol; 2004 Sep 13; 498(1-3):249-56. PubMed ID: 15364002
    [Abstract] [Full Text] [Related]

  • 30. The mu- and delta-opioid pharmacophore conformations of cyclic beta-casomorphin analogues indicate docking of the Phe3 residue to different domains of the opioid receptors.
    Brandt W, Stoldt M, Schinke H.
    J Comput Aided Mol Des; 1996 Jun 13; 10(3):201-12. PubMed ID: 8808737
    [Abstract] [Full Text] [Related]

  • 31. In vitro potency, affinity and agonist efficacy of highly selective delta opioid receptor ligands.
    Kramer TH, Davis P, Hruby VJ, Burks TF, Porreca F.
    J Pharmacol Exp Ther; 1993 Aug 13; 266(2):577-84. PubMed ID: 8394911
    [Abstract] [Full Text] [Related]

  • 32. Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) and related novel nonpeptide delta opioid receptor ligands.
    Calderon SN, Rice KC, Rothman RB, Porreca F, Flippen-Anderson JL, Kayakiri H, Xu H, Becketts K, Smith LE, Bilsky EJ, Davis P, Horvath R.
    J Med Chem; 1997 Feb 28; 40(5):695-704. PubMed ID: 9057856
    [Abstract] [Full Text] [Related]

  • 33. Pharmacologic evaluation of a cyclic somatostatin analog with antagonist activity at mu opioid receptors in vitro.
    Shook JE, Pelton JT, Wire WS, Hirning LD, Hruby VJ, Burks TF.
    J Pharmacol Exp Ther; 1987 Mar 28; 240(3):772-7. PubMed ID: 2882015
    [Abstract] [Full Text] [Related]

  • 34. [D-Pen2,D-Pen5]enkephalin analogues with increased affinity and selectivity for delta opioid receptors.
    Toth G, Kramer TH, Knapp R, Lui G, Davis P, Burks TF, Yamamura HI, Hruby VJ.
    J Med Chem; 1990 Jan 28; 33(1):249-53. PubMed ID: 2153205
    [Abstract] [Full Text] [Related]

  • 35. Para-substituted Phe3 deltorphin analogues: enhanced selectivity of halogenated derivatives for delta opioid receptor sites.
    Salvadori S, Bianchi C, Lazarus LH, Scaranari V, Attila M, Tomatis R.
    J Med Chem; 1992 Dec 11; 35(25):4651-7. PubMed ID: 1335080
    [Abstract] [Full Text] [Related]

  • 36. Ring substituted and other conformationally constrained tyrosine analogues of [D-Pen2,D-Pen5]enkephalin with delta opioid receptor selectivity.
    Toth G, Russell KC, Landis G, Kramer TH, Fang L, Knapp R, Davis P, Burks TF, Yamamura HI, Hruby VJ.
    J Med Chem; 1992 Jun 26; 35(13):2384-91. PubMed ID: 1320122
    [Abstract] [Full Text] [Related]

  • 37. Conformational analysis of beta-methyl-para-nitrophenylalanine stereoisomers of cyclo[D-Pen2, D-Pen5]enkephalin by NMR spectroscopy and conformational energy calculations.
    Shenderovich MD, Kövér KE, Nikiforovich GV, Jiao D, Hruby VJ.
    Biopolymers; 1996 Feb 26; 38(2):141-56. PubMed ID: 8589249
    [Abstract] [Full Text] [Related]

  • 38. Conformational features responsible for the binding of cyclic analogues of enkephalin to opioid receptors. III. Probable binding conformations of mu-agonists with phenylalanine in position 3.
    Shenderovich MD, Nikiforovich GV, Golbraikh AA.
    Int J Pept Protein Res; 1991 Apr 26; 37(4):241-51. PubMed ID: 1654306
    [Abstract] [Full Text] [Related]

  • 39. Structure-activity relationships of cyclic beta-casomorphin-5 analogues.
    Schmidt R, Neubert K, Barth A, Liebmann C, Schnittler M, Chung NN, Schiller PW.
    Peptides; 1991 Apr 26; 12(6):1175-80. PubMed ID: 1667685
    [Abstract] [Full Text] [Related]

  • 40. Synthesis of stable and potent delta/mu opioid peptides: analogues of H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-OH by ring-closing metathesis.
    Mollica A, Guardiani G, Davis P, Ma SW, Porreca F, Lai J, Mannina L, Sobolev AP, Hruby VJ.
    J Med Chem; 2007 Jun 28; 50(13):3138-42. PubMed ID: 17539621
    [Abstract] [Full Text] [Related]

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