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Journal Abstract Search

369 related items for PubMed ID: 8012813

  • 1. Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence.
    Shen KF, Crain SM.
    Brain Res; 1994 Feb 14; 636(2):286-97. PubMed ID: 8012813
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  • 2. Biphalin, an enkephalin analog with unexpectedly high antinociceptive potency and low dependence liability in vivo, selectively antagonizes excitatory opioid receptor functions of sensory neurons in culture.
    Shen KF, Crain SM.
    Brain Res; 1995 Dec 01; 701(1-2):158-66. PubMed ID: 8925279
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  • 3. Etorphine elicits anomalous excitatory opioid effects on sensory neurons treated with GM1 ganglioside or pertussis toxin in contrast to its potent inhibitory effects on naive or chronic morphine-treated cells.
    Crain SM, Shen KF.
    Brain Res; 1996 Nov 25; 741(1-2):275-83. PubMed ID: 9001733
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  • 5. Chronic selective activation of excitatory opioid receptor functions in sensory neurons results in opioid 'dependence' without tolerance.
    Shen KF, Crain SM.
    Brain Res; 1992 Nov 27; 597(1):74-83. PubMed ID: 1335822
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  • 7. Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment.
    Crain SM, Shen KF.
    Proc Natl Acad Sci U S A; 1995 Nov 07; 92(23):10540-4. PubMed ID: 7479836
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  • 9. Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture.
    Shen KF, Crain SM.
    Brain Res; 1989 Jul 10; 491(2):227-42. PubMed ID: 2548663
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  • 11. After GM1 ganglioside treatment of sensory neurons naloxone paradoxically prolongs the action potential but still antagonizes opioid inhibition.
    Crain SM, Shen KF.
    J Pharmacol Exp Ther; 1992 Jan 10; 260(1):182-6. PubMed ID: 1731037
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  • 16. Acute thermal hyperalgesia elicited by low-dose morphine in normal mice is blocked by ultra-low-dose naltrexone, unmasking potent opioid analgesia.
    Crain SM, Shen KF.
    Brain Res; 2001 Jan 05; 888(1):75-82. PubMed ID: 11146054
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  • 19. Chronic opioid treatment of neuroblastoma x dorsal root ganglion neuron hybrid F11 cells results in elevated GM1 ganglioside and cyclic adenosine monophosphate levels and onset of naloxone-evoked decreases in membrane K+ currents.
    Wu G, Fan SF, Lu ZH, Ledeen RW, Crain SM.
    J Neurosci Res; 1995 Nov 01; 42(4):493-503. PubMed ID: 8568936
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  • 20. Opioids at low concentration decrease openings of K+ channels in sensory ganglion neurons.
    Fan SF, Shen KF, Crain SM.
    Brain Res; 1991 Aug 30; 558(1):166-70. PubMed ID: 1682013
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