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Journal Abstract Search


126 related items for PubMed ID: 8013642

  • 1. Application of 13C NMR spectroscopy to paratope mapping for larger antigen-Fab complexes.
    Kim H, Kato K, Yamato S, Igarashi T, Matsunaga C, Ohtsuka H, Higuchi A, Nomura N, Noguchi H, Arata Y.
    FEBS Lett; 1994 Jun 13; 346(2-3):246-50. PubMed ID: 8013642
    [Abstract] [Full Text] [Related]

  • 2. Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3.
    Jung SH, Pastan I, Lee B.
    Proteins; 1994 May 13; 19(1):35-47. PubMed ID: 8066084
    [Abstract] [Full Text] [Related]

  • 3. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I, Padlan EA, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1994 Dec 06; 91(25):12051-5. PubMed ID: 7991583
    [Abstract] [Full Text] [Related]

  • 4. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.
    Reiter Y, Brinkmann U, Webber KO, Jung SH, Lee B, Pastan I.
    Protein Eng; 1994 May 06; 7(5):697-704. PubMed ID: 8073039
    [Abstract] [Full Text] [Related]

  • 5. Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions.
    Reiter Y, Brinkmann U, Kreitman RJ, Jung SH, Lee B, Pastan I.
    Biochemistry; 1994 May 10; 33(18):5451-9. PubMed ID: 7910034
    [Abstract] [Full Text] [Related]

  • 6. Role of the domain-domain interaction in the construction of the antigen combining site. A comparative study by 1H-15N shift correlation NMR spectroscopy of the Fv and Fab fragments of anti-dansyl mouse monoclonal antibody.
    Takahashi H, Tamura H, Shimba N, Shimada I, Arata Y.
    J Mol Biol; 1994 Oct 28; 243(3):494-503. PubMed ID: 7966275
    [Abstract] [Full Text] [Related]

  • 7. Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
    Li Y, Li H, Smith-Gill SJ, Mariuzza RA.
    Biochemistry; 2000 May 30; 39(21):6296-309. PubMed ID: 10828942
    [Abstract] [Full Text] [Related]

  • 8. B3(Fab)-PE38M: a recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3.
    Choe M, Webber KO, Pastan I.
    Cancer Res; 1994 Jul 01; 54(13):3460-7. PubMed ID: 8012967
    [Abstract] [Full Text] [Related]

  • 9. Functional mapping of conserved residues located at the VL and VH domain interface of a Fab.
    Chatellier J, Van Regenmortel MH, Vernet T, Altschuh D.
    J Mol Biol; 1996 Nov 22; 264(1):1-6. PubMed ID: 8950262
    [Abstract] [Full Text] [Related]

  • 10. Biochemical and immunochemical studies of proteolytic fragments of exotoxin A from Pseudomonas aeruginosa.
    Bourdenet S, Vacheron MJ, Guinand M, Michel G, Arminjon F.
    Eur J Biochem; 1990 Sep 11; 192(2):379-85. PubMed ID: 2170123
    [Abstract] [Full Text] [Related]

  • 11. Improved binding and antitumor activity of a recombinant anti-erbB2 immunotoxin by disulfide stabilization of the Fv fragment.
    Reiter Y, Brinkmann U, Jung SH, Lee B, Kasprzyk PG, King CR, Pastan I.
    J Biol Chem; 1994 Jul 15; 269(28):18327-31. PubMed ID: 7913461
    [Abstract] [Full Text] [Related]

  • 12. Structural and dynamic properties of the Fv fragment and the single-chain Fv fragment of an antibody in solution investigated by heteronuclear three-dimensional NMR spectroscopy.
    Freund C, Ross A, Plückthun A, Holak TA.
    Biochemistry; 1994 Mar 22; 33(11):3296-303. PubMed ID: 8136365
    [Abstract] [Full Text] [Related]

  • 13. A comparative analysis of the immunological evolution of antibody 28B4.
    Yin J, Mundorff EC, Yang PL, Wendt KU, Hanway D, Stevens RC, Schultz PG.
    Biochemistry; 2001 Sep 11; 40(36):10764-73. PubMed ID: 11535051
    [Abstract] [Full Text] [Related]

  • 14. Diphtheria toxin and Pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism.
    Wilson BA, Collier RJ.
    Curr Top Microbiol Immunol; 1992 Sep 11; 175():27-41. PubMed ID: 1628498
    [No Abstract] [Full Text] [Related]

  • 15. Carbon-13 NMR study of switch variant anti-dansyl antibodies: antigen binding and domain-domain interactions.
    Kato K, Matsunaga C, Odaka A, Yamato S, Takaha W, Shimada I, Arata Y.
    Biochemistry; 1991 Jul 02; 30(26):6604-10. PubMed ID: 2054358
    [Abstract] [Full Text] [Related]

  • 16. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U, Lee BK, Pastan I.
    J Immunol; 1993 Apr 01; 150(7):2774-82. PubMed ID: 8454854
    [Abstract] [Full Text] [Related]

  • 17. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin.
    Brinkmann U, Gallo M, Brinkmann E, Kunwar S, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Jan 15; 90(2):547-51. PubMed ID: 8421689
    [Abstract] [Full Text] [Related]

  • 18. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I, Pastan I.
    J Biol Chem; 1995 Oct 06; 270(40):23373-80. PubMed ID: 7559495
    [Abstract] [Full Text] [Related]

  • 19. A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
    Brinkmann U, Reiter Y, Jung SH, Lee B, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Aug 15; 90(16):7538-42. PubMed ID: 8356052
    [Abstract] [Full Text] [Related]

  • 20. The structure of Pseudomonas exotoxin A as a guide to rational design.
    Nicholls PJ, Youle RJ.
    Targeted Diagn Ther; 1992 Aug 15; 7():439-46. PubMed ID: 1633305
    [No Abstract] [Full Text] [Related]


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