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Journal Abstract Search

409 related items for PubMed ID: 8022791

  • 1. Fatty acid synthesis: a potential selective target for antineoplastic therapy.
    Kuhajda FP, Jenner K, Wood FD, Hennigar RA, Jacobs LB, Dick JD, Pasternack GR.
    Proc Natl Acad Sci U S A; 1994 Jul 05; 91(14):6379-83. PubMed ID: 8022791
    [Abstract] [Full Text] [Related]

  • 2. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
    Thupari JN, Pinn ML, Kuhajda FP.
    Biochem Biophys Res Commun; 2001 Jul 13; 285(2):217-23. PubMed ID: 11444828
    [Abstract] [Full Text] [Related]

  • 3. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.
    Pizer ES, Thupari J, Han WF, Pinn ML, Chrest FJ, Frehywot GL, Townsend CA, Kuhajda FP.
    Cancer Res; 2000 Jan 15; 60(2):213-8. PubMed ID: 10667561
    [Abstract] [Full Text] [Related]

  • 4. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 15; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 5. Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells.
    Pizer ES, Wood FD, Pasternack GR, Kuhajda FP.
    Cancer Res; 1996 Feb 15; 56(4):745-51. PubMed ID: 8631008
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
    Menendez JA, Colomer R, Lupu R.
    Med Hypotheses; 2005 Feb 15; 64(2):337-41. PubMed ID: 15607568
    [Abstract] [Full Text] [Related]

  • 7. Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer.
    Shurbaji MS, Kalbfleisch JH, Thurmond TS.
    Hum Pathol; 1996 Sep 15; 27(9):917-21. PubMed ID: 8816886
    [Abstract] [Full Text] [Related]

  • 8. Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes.
    Kawaguchi A, Arai K, Seyama Y, Yamakawa T, Okuda S.
    J Biochem; 1980 Aug 15; 88(2):303-6. PubMed ID: 7419496
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of unsaturated fatty acid synthesis in escherichia coli by the antibiotic cerulenin.
    Buttke TM, Ingram LO.
    Biochemistry; 1978 Nov 28; 17(24):5282-6. PubMed ID: 365224
    [Abstract] [Full Text] [Related]

  • 10. Reversal of cerulenin-induced inhibition of phospholipids and sterol synthesis by exogenous fatty acids/sterols in Epidermophyton floccosum.
    Sanadi S, Pandey R, Khuller GK.
    Biochim Biophys Acta; 1987 Sep 25; 921(2):341-6. PubMed ID: 3651491
    [Abstract] [Full Text] [Related]

  • 11. The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids.
    Weaire PJ, Kekwick RG.
    Biochem J; 1975 Feb 25; 146(2):439-45. PubMed ID: 1156381
    [Abstract] [Full Text] [Related]

  • 12. Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris.
    Walker TA, Jonak ZL, Worsham LM, Ernst-Fonberg ML.
    Biochem J; 1981 Nov 01; 199(2):383-92. PubMed ID: 6803763
    [Abstract] [Full Text] [Related]

  • 13. De novo fatty acid synthesis and fatty acid elongation catalyzed by subcellular fractions from hog and human aorta.
    Slakey LL, Ferrick TJ, Ness GC, Porter JW.
    Lipids; 1979 May 01; 14(5):451-7. PubMed ID: 459710
    [Abstract] [Full Text] [Related]

  • 14. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
    Menendez JA, Ropero S, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Jun 01; 24(6):1369-83. PubMed ID: 15138577
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells.
    Pizer ES, Jackisch C, Wood FD, Pasternack GR, Davidson NE, Kuhajda FP.
    Cancer Res; 1996 Jun 15; 56(12):2745-7. PubMed ID: 8665507
    [Abstract] [Full Text] [Related]

  • 16. Purification and characterization of an unusually large fatty acid synthase from Mycobacterium tuberculosis var. bovis BCG.
    Kikuchi S, Rainwater DL, Kolattukudy PE.
    Arch Biochem Biophys; 1992 Jun 15; 295(2):318-26. PubMed ID: 1586161
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
    Lupu R, Menendez JA.
    Curr Pharm Biotechnol; 2006 Dec 15; 7(6):483-93. PubMed ID: 17168665
    [Abstract] [Full Text] [Related]

  • 18. Lipid biosynthesis in the sebaceous glands: synthesis of multibranched fatty acids from methylmalonyl-coenzyme A in cell-free preparations from the uropygial gland of goose.
    Buckner JS, Kolattukudy PE.
    Biochemistry; 1975 Apr 22; 14(8):1774-82. PubMed ID: 235967
    [Abstract] [Full Text] [Related]

  • 19. Improved pinocembrin production in Escherichia coli by engineering fatty acid synthesis.
    Cao W, Ma W, Zhang B, Wang X, Chen K, Li Y, Ouyang P.
    J Ind Microbiol Biotechnol; 2016 Apr 22; 43(4):557-66. PubMed ID: 26733394
    [Abstract] [Full Text] [Related]

  • 20. Regulation of fatty acid synthesis and malonyl-CoA content in mouse brown adipose tissue in response to cold-exposure, starvation or re-feeding.
    Buckley MG, Rath EA.
    Biochem J; 1987 Apr 15; 243(2):437-42. PubMed ID: 2888457
    [Abstract] [Full Text] [Related]

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