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168 related items for PubMed ID: 8028508

  • 1. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 2. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

  • 3. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 4. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 5. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 6. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in the rat ileum: effects of bile acids and lovastatin.
    Nguyen LB, Shefer S, Salen G, Ness GC, Batta A, Chowdhary IR, Paroulek E, Hauser S.
    Metabolism; 1994 Nov; 43(11):1446-50. PubMed ID: 7968602
    [Abstract] [Full Text] [Related]

  • 7. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 8. Mechanisms for cholesterol homeostasis in rat jejunal mucosa: effects of cholesterol, sitosterol, and lovastatin.
    Nguyen LB, Shefer S, Salen G, Tint GS, Ruiz F, Bullock J.
    J Lipid Res; 2001 Feb; 42(2):195-200. PubMed ID: 11181748
    [Abstract] [Full Text] [Related]

  • 9. Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin.
    Nguyen L, Salen G, Shefer S, Shore V, Tint GS, Ness G.
    Arteriosclerosis; 1990 Feb; 10(2):289-97. PubMed ID: 2317163
    [Abstract] [Full Text] [Related]

  • 10. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 11. Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
    Nguyen LB, Shefer S, Salen G, Tint SG, Batta AK.
    Proc Assoc Am Physicians; 1998 Dec; 110(1):32-9. PubMed ID: 9460081
    [Abstract] [Full Text] [Related]

  • 12. Sitosterolemia: exclusion of genes involved in reduced cholesterol biosynthesis.
    Patel SB, Honda A, Salen G.
    J Lipid Res; 1998 May; 39(5):1055-61. PubMed ID: 9610773
    [Abstract] [Full Text] [Related]

  • 13. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

  • 14. Inverse relationship between plasma cholestanol concentrations and bile acid synthesis in sitosterolemia.
    Salen G, Batta AK, Tint GS, Shefer S, Ness GC.
    J Lipid Res; 1994 Oct; 35(10):1878-87. PubMed ID: 7852865
    [Abstract] [Full Text] [Related]

  • 15. 3-Hydroxy-3-methylglutaryl coenzyme A reductase in isolated villous and crypt cells of the rat ileum.
    Merchant JL, Heller RA.
    J Lipid Res; 1977 Nov; 18(6):722-33. PubMed ID: 925517
    [Abstract] [Full Text] [Related]

  • 16. Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities.
    Honda A, Salen G, Nguyen LB, Xu G, Tint GS, Batta AK, Shefer S.
    Hepatology; 1998 Jan; 27(1):154-9. PubMed ID: 9425931
    [Abstract] [Full Text] [Related]

  • 17. [Activities of 3-hydroxyl-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and the rate of mevalonic acid, squalene, sterol and fatty acid biosynthesis from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: effects of Triton WR 1339, starvation and cholesterol diet].
    Poliakova ED, Dizhe EB, Klimova TA, Denisenko TV, Vasil'eva LE.
    Biokhimiia; 1981 Feb; 46(2):296-305. PubMed ID: 6113854
    [Abstract] [Full Text] [Related]

  • 18. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
    Jesch ED, Seo JM, Carr TP, Lee JY.
    Nutr Res; 2009 Dec; 29(12):859-66. PubMed ID: 19963159
    [Abstract] [Full Text] [Related]

  • 19. Regulation of acylcoenzyme A. Cholesterol acyltransferase and 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by lipoproteins in the intestine of parabiont rats.
    Purdy BH, Field FJ.
    J Clin Invest; 1984 Aug; 74(2):351-7. PubMed ID: 6746898
    [Abstract] [Full Text] [Related]

  • 20. Hydroxymethylglutaryl-coenzyme A reductase exhibits graded distribution in normal and mevinolin-treated ileum.
    Singer II, Kawka DW, McNally SE, Scott S, Alberts AW, Chen JS, Huff JW.
    Arteriosclerosis; 1987 Aug; 7(2):144-51. PubMed ID: 3555431
    [Abstract] [Full Text] [Related]

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