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PUBMED FOR HANDHELDS

Journal Abstract Search


260 related items for PubMed ID: 8031789

  • 1. Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways.
    Hood DB, Huntington JA, Gettins PG.
    Biochemistry; 1994 Jul 19; 33(28):8538-47. PubMed ID: 8031789
    [Abstract] [Full Text] [Related]

  • 2. The P6-P2 region of serpins is critical for proteinase inhibition and complex stability.
    Chaillan-Huntington CE, Gettins PG, Huntington JA, Patston PA.
    Biochemistry; 1997 Aug 05; 36(31):9562-70. PubMed ID: 9236002
    [Abstract] [Full Text] [Related]

  • 3. Influence of the P5 residue on alpha1-proteinase inhibitor mechanism.
    Chaillan-Huntington CE, Patston PA.
    J Biol Chem; 1998 Feb 20; 273(8):4569-73. PubMed ID: 9468513
    [Abstract] [Full Text] [Related]

  • 4. Single amino acid substitutions in recombinant plant-derived human α1-proteinase inhibitor confer enhanced stability and functional efficacy.
    Jha S, Sanyal I, Amla DV.
    Biochim Biophys Acta; 2014 Jan 20; 1840(1):416-27. PubMed ID: 24090883
    [Abstract] [Full Text] [Related]

  • 5. alpha1-Proteinase inhibitor forms initial non-covalent and final covalent complexes with elastase analogously to other serpin-proteinase pairs, suggesting a common mechanism of inhibition.
    Dobó J, Gettins PG.
    J Biol Chem; 2004 Mar 05; 279(10):9264-9. PubMed ID: 14593107
    [Abstract] [Full Text] [Related]

  • 6. Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.
    Filion ML, Bhakta V, Nguyen LH, Liaw PS, Sheffield WP.
    Biochemistry; 2004 Nov 23; 43(46):14864-72. PubMed ID: 15544357
    [Abstract] [Full Text] [Related]

  • 7. Formation of a noncovalent serpin-proteinase complex involves no conformational change in the serpin. Use of 1H-15N HSQC NMR as a sensitive nonperturbing monitor of conformation.
    Peterson FC, Gordon NC, Gettins PG.
    Biochemistry; 2000 Oct 03; 39(39):11884-92. PubMed ID: 11009600
    [Abstract] [Full Text] [Related]

  • 8. Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase.
    Dementiev A, Dobó J, Gettins PG.
    J Biol Chem; 2006 Feb 10; 281(6):3452-7. PubMed ID: 16321984
    [Abstract] [Full Text] [Related]

  • 9. Insight into the mechanism of serpin-proteinase inhibition from 2D [1H-15N] NMR studies of the 69 kDa alpha 1-proteinase inhibitor Pittsburgh-trypsin covalent complex.
    Peterson FC, Gettins PG.
    Biochemistry; 2001 May 29; 40(21):6284-92. PubMed ID: 11371190
    [Abstract] [Full Text] [Related]

  • 10. Role of the P6-P3' region of the serpin reactive loop in the formation and breakdown of the inhibitory complex.
    Plotnick MI, Schechter NM, Wang ZM, Liu X, Rubin H.
    Biochemistry; 1997 Nov 25; 36(47):14601-8. PubMed ID: 9398179
    [Abstract] [Full Text] [Related]

  • 11. Serpin conformational change in ovalbumin. Enhanced reactive center loop insertion through hinge region mutations.
    Huntington JA, Fan B, Karlsson KE, Deinum J, Lawrence DA, Gettins PG.
    Biochemistry; 1997 May 06; 36(18):5432-40. PubMed ID: 9154925
    [Abstract] [Full Text] [Related]

  • 12. Role of the P2 residue of human alpha 1-antitrypsin in determining target protease specificity.
    Chung HS, Kim JS, Lee SM, Park SJ.
    PLoS One; 2017 May 06; 12(9):e0185074. PubMed ID: 28922398
    [Abstract] [Full Text] [Related]

  • 13. S-ovalbumin, an ovalbumin conformer with properties analogous to those of loop-inserted serpins.
    Huntington JA, Patston PA, Gettins PG.
    Protein Sci; 1995 Apr 06; 4(4):613-21. PubMed ID: 7613461
    [Abstract] [Full Text] [Related]

  • 14.
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  • 15. Inhibitory activity and conformational transition of alpha 1-proteinase inhibitor variants.
    Schulze AJ, Huber R, Degryse E, Speck D, Bischoff R.
    Eur J Biochem; 1991 Dec 18; 202(3):1147-55. PubMed ID: 1765073
    [Abstract] [Full Text] [Related]

  • 16. Effects of mutations in the hinge region of serpins.
    Hopkins PC, Carrell RW, Stone SR.
    Biochemistry; 1993 Aug 03; 32(30):7650-7. PubMed ID: 8347575
    [Abstract] [Full Text] [Related]

  • 17. Functional diversification during evolution of the murine alpha(1)-proteinase inhibitor family: role of the hypervariable reactive center loop.
    Barbour KW, Goodwin RL, Guillonneau F, Wang Y, Baumann H, Berger FG.
    Mol Biol Evol; 2002 May 03; 19(5):718-27. PubMed ID: 11961105
    [Abstract] [Full Text] [Related]

  • 18. Evidence for the extent of insertion of the active site loop of intact alpha 1 proteinase inhibitor in beta-sheet A.
    Schulze AJ, Frohnert PW, Engh RA, Huber R.
    Biochemistry; 1992 Aug 25; 31(33):7560-5. PubMed ID: 1510942
    [Abstract] [Full Text] [Related]

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  • 20. Differential inhibition of serine proteinases by rabbit alpha 1-proteinase inhibitors F and S.
    Koj A, Regoeczi E.
    Int J Pept Protein Res; 1981 Apr 25; 17(4):519-26. PubMed ID: 6458574
    [Abstract] [Full Text] [Related]


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