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Journal Abstract Search

589 related items for PubMed ID: 8043020

  • 1. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC, Jones DR, Wrighton SA, Hall SD.
    Biochem Pharmacol; 1994 Jul 05; 48(1):173-82. PubMed ID: 8043020
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  • 2. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Schmider J, Harmatz JS, Shader RI.
    J Pharm Pharmacol; 1998 Sep 05; 50(9):997-1004. PubMed ID: 9811160
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  • 6. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct 05; 30(10):955-69. PubMed ID: 11315104
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  • 9. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    Wen X, Wang JS, Neuvonen PJ, Backman JT.
    Eur J Clin Pharmacol; 2002 Jan 05; 57(11):799-804. PubMed ID: 11868802
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  • 10. In-vitro characterization of the cytochrome P450 isoenzymes involved in the back oxidation and N-dealkylation of reduced haloperidol.
    Pan LP, De Vriendt C, Belpaire FM.
    Pharmacogenetics; 1998 Oct 05; 8(5):383-9. PubMed ID: 9825830
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  • 11. Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes.
    Wang Y, Unadkat JD.
    Biopharm Drug Dispos; 1999 Oct 05; 20(7):341-6. PubMed ID: 10760842
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  • 13. Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms.
    Renwick AB, Mistry H, Ball SE, Walters DG, Kao J, Lake BG.
    Xenobiotica; 1998 Apr 05; 28(4):337-48. PubMed ID: 9604298
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  • 15. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D.
    Drug Metab Dispos; 1997 May 05; 25(5):623-30. PubMed ID: 9152603
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  • 16. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep 05; 24(9):948-54. PubMed ID: 8886603
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  • 18. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X, Wang JS, Kivistö KT, Neuvonen PJ, Backman JT.
    Br J Clin Pharmacol; 2001 Nov 05; 52(5):547-53. PubMed ID: 11736863
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  • 19. Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC, Hall SD, Jones DR, VandenBranden M, Wrighton SA.
    Biochem Pharmacol; 1994 Apr 29; 47(9):1643-53. PubMed ID: 8185679
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  • 20. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S, Fujimaki Y, Yokoyama H, Okazaki O, Sudo K.
    Drug Metab Dispos; 2005 Nov 29; 33(11):1628-36. PubMed ID: 16049129
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