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Journal Abstract Search


119 related items for PubMed ID: 8055912

  • 1. Activation of the protein tyrosine kinase tyk2 by interferon alpha/beta.
    Barbieri G, Velazquez L, Scrobogna M, Fellous M, Pellegrini S.
    Eur J Biochem; 1994 Jul 15; 223(2):427-35. PubMed ID: 8055912
    [Abstract] [Full Text] [Related]

  • 2. Mutant cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3 alpha components.
    Loh JE, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Flavell RA.
    Mol Cell Biol; 1994 Mar 15; 14(3):2170-9. PubMed ID: 8114747
    [Abstract] [Full Text] [Related]

  • 3. Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.
    Velazquez L, Mogensen KE, Barbieri G, Fellous M, Uzé G, Pellegrini S.
    J Biol Chem; 1995 Feb 17; 270(7):3327-34. PubMed ID: 7531704
    [Abstract] [Full Text] [Related]

  • 4. Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase.
    Rani MR, Leaman DW, Han Y, Leung S, Croze E, Fish EN, Wolfman A, Ransohoff RM.
    J Biol Chem; 1999 Nov 05; 274(45):32507-11. PubMed ID: 10542297
    [Abstract] [Full Text] [Related]

  • 5. Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription.
    Eilers A, Kanda K, Klose B, Krolewski J, Decker T.
    Cell Growth Differ; 1996 Jun 05; 7(6):833-40. PubMed ID: 8780896
    [Abstract] [Full Text] [Related]

  • 6. Induction of beta-R1/I-TAC by interferon-beta requires catalytically active TYK2.
    Rani MR, Gauzzi C, Pellegrini S, Fish EN, Wei T, Ransohoff RM.
    J Biol Chem; 1999 Jan 22; 274(4):1891-7. PubMed ID: 9890942
    [Abstract] [Full Text] [Related]

  • 7. Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.
    Tai Z, Lin Y, He Y, Huang J, Guo J, Yang L, Zhang G, Wang F.
    Cell Signal; 2014 Mar 22; 26(3):619-28. PubMed ID: 24333668
    [Abstract] [Full Text] [Related]

  • 8. p135tyk2, an interferon-alpha-activated tyrosine kinase, is physically associated with an interferon-alpha receptor.
    Colamonici OR, Uyttendaele H, Domanski P, Yan H, Krolewski JJ.
    J Biol Chem; 1994 Feb 04; 269(5):3518-22. PubMed ID: 8106393
    [Abstract] [Full Text] [Related]

  • 9. Role of STAT2 in the alpha interferon signaling pathway.
    Leung S, Qureshi SA, Kerr IM, Darnell JE, Stark GR.
    Mol Cell Biol; 1995 Mar 04; 15(3):1312-7. PubMed ID: 7532278
    [Abstract] [Full Text] [Related]

  • 10. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.
    Watling D, Guschin D, Müller M, Silvennoinen O, Witthuhn BA, Quelle FW, Rogers NC, Schindler C, Stark GR, Ihle JN.
    Nature; 1993 Nov 11; 366(6451):166-70. PubMed ID: 7901766
    [Abstract] [Full Text] [Related]

  • 11. The Atlantic salmon protein tyrosine kinase Tyk2: molecular cloning, modulation of expression and function.
    Sobhkhez M, Hansen T, Iliev DB, Skjesol A, Jørgensen JB.
    Dev Comp Immunol; 2013 Dec 11; 41(4):553-63. PubMed ID: 23872231
    [Abstract] [Full Text] [Related]

  • 12. The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha.
    Li S, Labrecque S, Gauzzi MC, Cuddihy AR, Wong AH, Pellegrini S, Matlashewski GJ, Koromilas AE.
    Oncogene; 1999 Oct 14; 18(42):5727-37. PubMed ID: 10523853
    [Abstract] [Full Text] [Related]

  • 13. Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C.
    Radaeva S, Jaruga B, Kim WH, Heller T, Liang TJ, Gao B.
    Biochem J; 2004 Apr 01; 379(Pt 1):199-208. PubMed ID: 14690454
    [Abstract] [Full Text] [Related]

  • 14. IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7.
    Sancéau J, Hiscott J, Delattre O, Wietzerbin J.
    Oncogene; 2000 Jul 13; 19(30):3372-83. PubMed ID: 10918594
    [Abstract] [Full Text] [Related]

  • 15. Homodimerization and intermolecular tyrosine phosphorylation of the Tyk-2 tyrosine kinase.
    Domanski P, Yan H, Witte MM, Krolewski J, Colamonici OR.
    FEBS Lett; 1995 Nov 06; 374(3):317-22. PubMed ID: 7589562
    [Abstract] [Full Text] [Related]

  • 16. The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of Jak-Stat tyrosine phosphorylation.
    Novick D, Nabioullin RR, Ragsdale W, McKenna S, Weiser W, Garone L, Burkins C, Kim SH, Rubinstein M, Tepper MA, Arulanandam AR.
    J Interferon Cytokine Res; 2000 Nov 06; 20(11):971-82. PubMed ID: 11096454
    [Abstract] [Full Text] [Related]

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  • 19. Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase.
    Gauzzi MC, Velazquez L, McKendry R, Mogensen KE, Fellous M, Pellegrini S.
    J Biol Chem; 1996 Aug 23; 271(34):20494-500. PubMed ID: 8702790
    [Abstract] [Full Text] [Related]

  • 20. Activity of hybrid type I interferons in cells lacking Tyk2: a common region of IFN-alpha 8 induces a response, but IFN-alpha2/8 hybrids can behave like IFN-beta.
    Platis D, Foster GR.
    J Interferon Cytokine Res; 2003 Nov 23; 23(11):655-66. PubMed ID: 14651780
    [Abstract] [Full Text] [Related]


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