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119 related items for PubMed ID: 8055912
21. Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Karaghiosoff M, Steinborn R, Kovarik P, Kriegshäuser G, Baccarini M, Donabauer B, Reichart U, Kolbe T, Bogdan C, Leanderson T, Levy D, Decker T, Müller M. Nat Immunol; 2003 May; 4(5):471-7. PubMed ID: 12679810 [Abstract] [Full Text] [Related]
22. The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction. Müller M, Briscoe J, Laxton C, Guschin D, Ziemiecki A, Silvennoinen O, Harpur AG, Barbieri G, Witthuhn BA, Schindler C. Nature; 1993 Nov 11; 366(6451):129-35. PubMed ID: 8232552 [Abstract] [Full Text] [Related]
23. The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor. Gauzzi MC, Barbieri G, Richter MF, Uzé G, Ling L, Fellous M, Pellegrini S. Proc Natl Acad Sci U S A; 1997 Oct 28; 94(22):11839-44. PubMed ID: 9342324 [Abstract] [Full Text] [Related]
24. Interferon-induced nuclear signalling by Jak protein tyrosine kinases. Silvennoinen O, Ihle JN, Schlessinger J, Levy DE. Nature; 1993 Dec 09; 366(6455):583-5. PubMed ID: 7504785 [Abstract] [Full Text] [Related]
25. Tyk2 is essential for IFN-alpha-induced gene expression in mast cells. Mori Y, Hirose K, Suzuki K, Nakajima H, Seto Y, Ikeda K, Shimoda K, Nakayama K, Saito Y, Iwamoto I. Int Arch Allergy Immunol; 2004 Jun 09; 134 Suppl 1():25-9. PubMed ID: 15166480 [Abstract] [Full Text] [Related]
26. Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling. Takaoka A, Tanaka N, Mitani Y, Miyazaki T, Fujii H, Sato M, Kovarik P, Decker T, Schlessinger J, Taniguchi T. EMBO J; 1999 May 04; 18(9):2480-8. PubMed ID: 10228162 [Abstract] [Full Text] [Related]
27. A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling. Yeh TC, Dondi E, Uze G, Pellegrini S. Proc Natl Acad Sci U S A; 2000 Aug 01; 97(16):8991-6. PubMed ID: 10908660 [Abstract] [Full Text] [Related]
28. IFN-alpha beta secreted during infection is necessary but not sufficient for negative feedback regulation of IFN-alpha beta signaling by Mycobacterium tuberculosis. Prabhakar S, Qiao Y, Canova A, Tse DB, Pine R. J Immunol; 2005 Jan 15; 174(2):1003-12. PubMed ID: 15634924 [Abstract] [Full Text] [Related]
29. Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex. Constantinescu SN, Croze E, Wang C, Murti A, Basu L, Mullersman JE, Pfeffer LM. Proc Natl Acad Sci U S A; 1994 Sep 27; 91(20):9602-6. PubMed ID: 7524081 [Abstract] [Full Text] [Related]
30. The antiviral action of interferon is potentiated by removal of the conserved IRTAM domain of the IFNAR1 chain of the interferon alpha/beta receptor: effects on JAK-STAT activation and receptor down-regulation. Basu L, Yang CH, Murti A, Garcia JV, Croze E, Constantinescu SN, Mullersman JE, Pfeffer LM. Virology; 1998 Mar 01; 242(1):14-21. PubMed ID: 9501047 [Abstract] [Full Text] [Related]
31. Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcription. Komatsu T, Takeuchi K, Yokoo J, Tanaka Y, Gotoh B. J Virol; 2000 Mar 01; 74(5):2477-80. PubMed ID: 10666284 [Abstract] [Full Text] [Related]
32. Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell. Ho LJ, Hung LF, Weng CY, Wu WL, Chou P, Lin YL, Chang DM, Tai TY, Lai JH. J Immunol; 2005 Jun 15; 174(12):8163-72. PubMed ID: 15944325 [Abstract] [Full Text] [Related]
34. Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dependent mechanism. Nguyen VA, Chen J, Hong F, Ishac EJ, Gao B. Biochem J; 2000 Jul 15; 349(Pt 2):427-34. PubMed ID: 10880341 [Abstract] [Full Text] [Related]
35. TYK2 kinase activity is required for functional type I interferon responses in vivo. Prchal-Murphy M, Semper C, Lassnig C, Wallner B, Gausterer C, Teppner-Klymiuk I, Kobolak J, Müller S, Kolbe T, Karaghiosoff M, Dinnyés A, Rülicke T, Leitner NR, Strobl B, Müller M. PLoS One; 2012 Jul 15; 7(6):e39141. PubMed ID: 22723949 [Abstract] [Full Text] [Related]
36. IL-1 beta attenuates IFN-alpha beta-induced antiviral activity and STAT1 activation in the liver: involvement of proteasome-dependent pathway. Tian Z, Shen X, Feng H, Gao B. J Immunol; 2000 Oct 01; 165(7):3959-65. PubMed ID: 11034404 [Abstract] [Full Text] [Related]
38. Interferon-alpha signaling promotes nucleus-to-cytoplasmic redistribution of p95Vav, and formation of a multisubunit complex involving Vav, Ku80, and Tyk2. Adam L, Bandyopadhyay D, Kumar R. Biochem Biophys Res Commun; 2000 Jan 27; 267(3):692-6. PubMed ID: 10673353 [Abstract] [Full Text] [Related]