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166 related items for PubMed ID: 8070324

  • 1. Differences in the pharmacokinetic properties of orally administered all-trans-retinoic acid and 9-cis-retinoic acid in the plasma of nude mice.
    Achkar CC, Bentel JM, Boylan JF, Scher HI, Gudas LJ, Miller WH.
    Drug Metab Dispos; 1994; 22(3):451-8. PubMed ID: 8070324
    [Abstract] [Full Text] [Related]

  • 2. Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid.
    Tzimas G, Nau H, Hendrickx AG, Peterson PE, Hummler H.
    Teratology; 1996 Nov; 54(5):255-65. PubMed ID: 9035347
    [Abstract] [Full Text] [Related]

  • 3. Clinical pharmacology of oral all-trans retinoic acid in patients with acute promyelocytic leukemia.
    Muindi JR, Frankel SR, Huselton C, DeGrazia F, Garland WA, Young CW, Warrell RP.
    Cancer Res; 1992 Apr 15; 52(8):2138-42. PubMed ID: 1559217
    [Abstract] [Full Text] [Related]

  • 4. Single versus multiple dose administration of all-trans-retinoic acid during organogenesis: differential metabolism and transplacental kinetics in rat and rabbit.
    Collins MD, Tzimas G, Bürgin H, Hummler H, Nau H.
    Toxicol Appl Pharmacol; 1995 Jan 15; 130(1):9-18. PubMed ID: 7839374
    [Abstract] [Full Text] [Related]

  • 5. The area under the concentration-time curve of all-trans-retinoic acid is the most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat.
    Tzimas G, Thiel R, Chahoud I, Nau H.
    Toxicol Appl Pharmacol; 1997 Apr 15; 143(2):436-44. PubMed ID: 9144460
    [Abstract] [Full Text] [Related]

  • 6. Placental transfer and developmental effects of 9-cis retinoic acid in mice.
    Kochhar DM, Jiang H, Penner JD, Heyman RA.
    Teratology; 1995 Apr 15; 51(4):257-65. PubMed ID: 7570368
    [Abstract] [Full Text] [Related]

  • 7. Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats.
    Collins MD, Tzimas G, Hummler H, Bürgin H, Nau H.
    Toxicol Appl Pharmacol; 1994 Jul 15; 127(1):132-44. PubMed ID: 8048045
    [Abstract] [Full Text] [Related]

  • 8. Identification of 9,13-dicis-retinoic acid as a major plasma metabolite of 9-cis-retinoic acid and limited transfer of 9-cis-retinoic acid and 9,13-dicis-retinoic acid to the mouse and rat embryos.
    Tzimas G, Sass JO, Wittfoht W, Elmazar MM, Ehlers K, Nau H.
    Drug Metab Dispos; 1994 Jul 15; 22(6):928-36. PubMed ID: 7895612
    [Abstract] [Full Text] [Related]

  • 9. Teratogenicity and transplacental pharmacokinetics of 13-cis-retinoic acid in rabbits.
    Eckhoff C, Chari S, Kromka M, Staudner H, Juhasz L, Rudiger H, Agnish N.
    Toxicol Appl Pharmacol; 1994 Mar 15; 125(1):34-41. PubMed ID: 8128493
    [Abstract] [Full Text] [Related]

  • 10. Plasma pharmacokinetics and metabolism of 13-cis- and all-trans-retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin.
    Kraft JC, Slikker W, Bailey JR, Roberts LG, Fischer B, Wittfoht W, Nau H.
    Drug Metab Dispos; 1991 Mar 15; 19(2):317-24. PubMed ID: 1676630
    [Abstract] [Full Text] [Related]

  • 11. Pharmacokinetic assessment of teratologically effective concentrations of an endogenous retinoic acid metabolite.
    Satre MA, Penner JD, Kochhar DM.
    Teratology; 1989 Apr 15; 39(4):341-8. PubMed ID: 2749577
    [Abstract] [Full Text] [Related]

  • 12. Pharmacokinetics of 13-cis-, all-trans-, 13-cis-4-oxo-, and all-trans-4-oxo retinoic acid after intravenous administration in the cynomolgus monkey.
    Sandberg JA, Eckhoff C, Nau H, Slikker W.
    Drug Metab Dispos; 1994 Apr 15; 22(1):154-60. PubMed ID: 8149876
    [Abstract] [Full Text] [Related]

  • 13. UV-induced isomerization of oral retinoids in vitro and in vivo in hairless mice.
    Berne B, Rollman O, Vahlquist A.
    Photodermatol Photoimmunol Photomed; 1990 Aug 15; 7(4):146-52. PubMed ID: 2150173
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetics of oral all-trans retinoic acid in patients with acute promyelocytic leukemia.
    Lefebvre P, Thomas G, Gourmel B, Agadir A, Castaigne S, Dreux C, Degos L, Chomienne C.
    Leukemia; 1991 Dec 15; 5(12):1054-8. PubMed ID: 1774953
    [Abstract] [Full Text] [Related]

  • 15. Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey.
    Hummler H, Hendrickx AG, Nau H.
    Teratology; 1994 Sep 15; 50(3):184-93. PubMed ID: 7871482
    [Abstract] [Full Text] [Related]

  • 16. Oxidative and reductive metabolism of 9-cis-retinoic acid in the rat. Identification of 13,14-dihydro-9-cis-retinoic acid and its taurine conjugate.
    Shirley MA, Bennani YL, Boehm MF, Breau AP, Pathirana C, Ulm EH.
    Drug Metab Dispos; 1996 Mar 15; 24(3):293-302. PubMed ID: 8820419
    [Abstract] [Full Text] [Related]

  • 17. Embryogenesis in cultured whole rat embryos after combined exposures to 3,3',5-triiodo-L-thyronine (T3) plus all-trans-retinoic acid and to T3 plus 9-cis-retinoic acid.
    Kraft JC, Willhite CC, Juchau MR.
    J Craniofac Genet Dev Biol; 1994 Mar 15; 14(2):75-86. PubMed ID: 8071425
    [Abstract] [Full Text] [Related]

  • 18. Time course of induction of metabolism of all-trans-retinoic acid and the up-regulation of cellular retinoic acid-binding protein.
    Adamson PC, Boylan JF, Balis FM, Murphy RF, Godwin KA, Gudas LJ, Poplack DG.
    Cancer Res; 1993 Feb 01; 53(3):472-6. PubMed ID: 8381046
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of oral 9-cis-retinoic acid in the human. Identification of 9-cis-retinoyl-beta-glucuronide and 9-cis-4-oxo-retinoyl-beta-glucuronide as urinary metabolites.
    Sass JO, Masgrau E, Saurat JH, Nau H.
    Drug Metab Dispos; 1995 Sep 01; 23(9):887-91. PubMed ID: 8565776
    [Abstract] [Full Text] [Related]

  • 20. 9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia.
    Miller WH, Jakubowski A, Tong WP, Miller VA, Rigas JR, Benedetti F, Gill GM, Truglia JA, Ulm E, Shirley M.
    Blood; 1995 Jun 01; 85(11):3021-7. PubMed ID: 7756637
    [Abstract] [Full Text] [Related]

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