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Journal Abstract Search

393 related items for PubMed ID: 8071856

  • 1. Competitive inhibition of human liver microsomal cytochrome P450 3A-dependent steroid 6 beta-hydroxylation activity by cyclophosphamide and ifosfamide in vitro.
    Murray M, Butler AM, Stupans I.
    J Pharmacol Exp Ther; 1994 Aug; 270(2):645-9. PubMed ID: 8071856
    [Abstract] [Full Text] [Related]

  • 2. Aryl acetylenes as mechanism-based inhibitors of cytochrome P450-dependent monooxygenase enzymes.
    Foroozesh M, Primrose G, Guo Z, Bell LC, Alworth WL, Guengerich FP.
    Chem Res Toxicol; 1997 Jan; 10(1):91-102. PubMed ID: 9074808
    [Abstract] [Full Text] [Related]

  • 3. Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard.
    Chang TK, Waxman DJ.
    Cancer Res; 1993 Jun 01; 53(11):2490-7. PubMed ID: 8495410
    [Abstract] [Full Text] [Related]

  • 4. Metabolism and binding of cyclophosphamide and its metabolite acrolein to rat hepatic microsomal cytochrome P-450.
    Marinello AJ, Bansal SK, Paul B, Koser PL, Love J, Struck RF, Gurtoo HL.
    Cancer Res; 1984 Oct 01; 44(10):4615-21. PubMed ID: 6380709
    [Abstract] [Full Text] [Related]

  • 5. Enhanced inhibition of microsomal cytochrome P450 3A2 in rat liver during diltiazem biotransformation.
    Murray M, Butler AM.
    J Pharmacol Exp Ther; 1996 Dec 01; 279(3):1447-52. PubMed ID: 8968370
    [Abstract] [Full Text] [Related]

  • 6. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver.
    Amato G, Longo V, Mazzaccaro A, Gervasi PG.
    Chem Res Toxicol; 1996 Dec 01; 9(5):882-90. PubMed ID: 8828925
    [Abstract] [Full Text] [Related]

  • 7. Denitrosation of the anti-cancer drug 1,3-bis(2-chloroethyl)-1-nitrosourea catalyzed by microsomal glutathione S-transferase and cytochrome P450 monooxygenases.
    Weber GF, Waxman DJ.
    Arch Biochem Biophys; 1993 Dec 01; 307(2):369-78. PubMed ID: 8274024
    [Abstract] [Full Text] [Related]

  • 8. Identification of a reversible component in the in vitro inhibition of rat hepatic cytochrome P450 2B1 by parathion.
    Murray M, Butler AM.
    J Pharmacol Exp Ther; 1995 Feb 01; 272(2):639-44. PubMed ID: 7853177
    [Abstract] [Full Text] [Related]

  • 9. Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450.
    Yu L, Waxman DJ.
    Drug Metab Dispos; 1996 Nov 01; 24(11):1254-62. PubMed ID: 8937861
    [Abstract] [Full Text] [Related]

  • 10. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb 01; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 11. Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide.
    Pekthong D, Martin H, Abadie C, Bonet A, Heyd B, Mantion G, Richert L.
    J Ethnopharmacol; 2008 Feb 12; 115(3):432-40. PubMed ID: 18053665
    [Abstract] [Full Text] [Related]

  • 12. Reversible and time-dependent inhibition of the hepatic cytochrome P450 steroidal hydroxylases by the proestrogenic pesticide methoxychlor in rat and human.
    Li HC, Mani C, Kupfer D.
    J Biochem Toxicol; 1993 Dec 12; 8(4):195-206. PubMed ID: 8114062
    [Abstract] [Full Text] [Related]

  • 13. Both cytochromes P450 2E1 and 3A are involved in the O-hydroxylation of p-nitrophenol, a catalytic activity known to be specific for P450 2E1.
    Zerilli A, Ratanasavanh D, Lucas D, Goasduff T, Dréano Y, Menard C, Picart D, Berthou F.
    Chem Res Toxicol; 1997 Oct 12; 10(10):1205-12. PubMed ID: 9348445
    [Abstract] [Full Text] [Related]

  • 14. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H, Nakano M, Imai Y, Ueng YF, Guengerich FP, Shimada T.
    Arch Biochem Biophys; 1996 Jan 15; 325(2):174-82. PubMed ID: 8561495
    [Abstract] [Full Text] [Related]

  • 15. Effects of bioflavonoids on hepatic P450 activities.
    Obermeier MT, White RE, Yang CS.
    Xenobiotica; 1995 Jun 15; 25(6):575-84. PubMed ID: 7483658
    [Abstract] [Full Text] [Related]

  • 16. Measurement of 4-hydroxylation of ifosfamide in human liver microsomes using the estimation of free and protein-bound acrolein and codetermination of keto- and carboxyifosfamide.
    Preiss R, Schmidt R, Baumann F, Hanschmann H, Hauss J, Geissler F, Pahlig H, Ratzewiss B.
    J Cancer Res Clin Oncol; 2002 Jul 15; 128(7):385-92. PubMed ID: 12136253
    [Abstract] [Full Text] [Related]

  • 17. Participation of P450 3A enzymes in rat hepatic microsomal retinoic acid 4-hydroxylation.
    Martini R, Murray M.
    Arch Biochem Biophys; 1993 May 15; 303(1):57-66. PubMed ID: 8489266
    [Abstract] [Full Text] [Related]

  • 18. Induction of cytochrome P450 2B1 in rat liver by the aromatase inhibitor aminoglutethimide.
    Murray M, Cantrill E, Farrell GC.
    J Pharmacol Exp Ther; 1993 Apr 15; 265(1):477-81. PubMed ID: 8474030
    [Abstract] [Full Text] [Related]

  • 19. Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes.
    Iribarne C, Berthou F, Baird S, Dréano Y, Picart D, Bail JP, Beaune P, Ménez JF.
    Chem Res Toxicol; 1996 Mar 15; 9(2):365-73. PubMed ID: 8839037
    [Abstract] [Full Text] [Related]

  • 20. Characterization of the selectivity and mechanism of cytochrome P450 inhibition by dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate.
    Kim JY, Baek M, Lee S, Kim SO, Dong MS, Kim BR, Kim DH.
    Drug Metab Dispos; 2001 Dec 15; 29(12):1555-60. PubMed ID: 11717174
    [Abstract] [Full Text] [Related]

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