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Journal Abstract Search

492 related items for PubMed ID: 8074451

  • 1. The role of glutathione (GSH) in determining sensitivity to platinum drugs in vivo in platinum-sensitive and -resistant murine leukaemia and plasmacytoma and human ovarian carcinoma xenografts.
    Goddard P, Valenti M, Kelland LR.
    Anticancer Res; 1994; 14(3A):1065-70. PubMed ID: 8074451
    [Abstract] [Full Text] [Related]

  • 2. cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice.
    Raynaud FI, Boxall FE, Goddard PM, Valenti M, Jones M, Murrer BA, Abrams M, Kelland LR.
    Clin Cancer Res; 1997 Nov; 3(11):2063-74. PubMed ID: 9815598
    [Abstract] [Full Text] [Related]

  • 3. Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.
    Kelland LR, Abel G, McKeage MJ, Jones M, Goddard PM, Valenti M, Murrer BA, Harrap KR.
    Cancer Res; 1993 Jun 01; 53(11):2581-6. PubMed ID: 8388318
    [Abstract] [Full Text] [Related]

  • 4. Novel trans platinum complexes: comparative in vitro and in vivo activity against platinum-sensitive and resistant murine tumours.
    Goddard PM, Orr RM, Valenti MR, Barnard CF, Murrer BA, Kelland LR, Harrap KR.
    Anticancer Res; 1996 Jun 01; 16(1):33-8. PubMed ID: 8615631
    [Abstract] [Full Text] [Related]

  • 5. Relationship of cellular glutathione to the cytotoxicity and resistance of seven platinum compounds.
    Meijer C, Mulder NH, Timmer-Bosscha H, Sluiter WJ, Meersma GJ, de Vries EG.
    Cancer Res; 1992 Dec 15; 52(24):6885-9. PubMed ID: 1458477
    [Abstract] [Full Text] [Related]

  • 6. The role of platinum uptake and glutathione levels in L1210 cells sensitive and resistant to cisplatin, tetraplatin or carboplatin.
    Nicolson MC, Orr RM, O'Neill CF, Harrap KR.
    Neoplasma; 1992 Dec 15; 39(3):189-95. PubMed ID: 1528325
    [Abstract] [Full Text] [Related]

  • 7. Role of glutathione in the in vitro synergism between 4-hydroperoxy-cyclophosphamide and cisplatin in leukemia cell lines.
    Peters RH, Jollow DJ, Stuart RK.
    Cancer Res; 1991 May 15; 51(10):2536-41. PubMed ID: 2021933
    [Abstract] [Full Text] [Related]

  • 8. Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell lines.
    Mistry P, Loh SY, Kelland LR, Harrap KR.
    Int J Cancer; 1993 Nov 11; 55(5):848-56. PubMed ID: 8244583
    [Abstract] [Full Text] [Related]

  • 9. The role of murine tumour models and their acquired platinum-resistant counterparts in the evaluation of novel platinum antitumour agents: a cautionary note.
    Goddard PM, Valenti MR, Harrap KR.
    Ann Oncol; 1991 Sep 11; 2(8):535-40. PubMed ID: 1793720
    [Abstract] [Full Text] [Related]

  • 10. Comparison of cellular accumulation and cytotoxicity of cisplatin with that of tetraplatin and amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human ovarian carcinoma cell lines.
    Mistry P, Kelland LR, Loh SY, Abel G, Murrer BA, Harrap KR.
    Cancer Res; 1992 Nov 15; 52(22):6188-93. PubMed ID: 1423261
    [Abstract] [Full Text] [Related]

  • 11. Pharmacokinetics of tetraplatin administered intraperitoneally with reduced glutathione in mice.
    Kido Y, Khokhar AR, Yoshida M, Thai GW, Siddik ZH.
    Drug Metab Dispos; 1994 Nov 15; 22(2):312-7. PubMed ID: 8013287
    [Abstract] [Full Text] [Related]

  • 12. Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines.
    Yoshida M, Khokhar AR, Siddik ZH.
    Cancer Res; 1994 Jul 01; 54(13):3468-73. PubMed ID: 8012968
    [Abstract] [Full Text] [Related]

  • 13. Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.
    Louie KG, Behrens BC, Kinsella TJ, Hamilton TC, Grotzinger KR, McKoy WM, Winker MA, Ozols RF.
    Cancer Res; 1985 May 01; 45(5):2110-5. PubMed ID: 3986765
    [Abstract] [Full Text] [Related]

  • 14. Role of carrier ligand in platinum resistance of human carcinoma cell lines.
    Schmidt W, Chaney SG.
    Cancer Res; 1993 Feb 15; 53(4):799-805. PubMed ID: 8428361
    [Abstract] [Full Text] [Related]

  • 15. Gene-specific repair of Pt/DNA lesions and induction of apoptosis by the oral platinum drug JM216 in three human ovarian carcinoma cell lines sensitive and resistant to cisplatin.
    O'Neill CF, Koberle B, Masters JR, Kelland LR.
    Br J Cancer; 1999 Dec 15; 81(8):1294-303. PubMed ID: 10604725
    [Abstract] [Full Text] [Related]

  • 16. Role of carrier ligand in platinum resistance in L1210 cells.
    Gibbons GR, Page JD, Mauldin SK, Husain I, Chaney SG.
    Cancer Res; 1990 Oct 15; 50(20):6497-501. PubMed ID: 2208108
    [Abstract] [Full Text] [Related]

  • 17. Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.
    Siddik ZH, Thai G, Yoshida M, Zhang YP, Khokhar AR.
    Anticancer Drug Des; 1994 Dec 15; 9(6):495-509. PubMed ID: 7880375
    [Abstract] [Full Text] [Related]

  • 18. Platinum coordination complexes which circumvent cisplatin resistance.
    Harrap KR, Kelland LR, Jones M, Goddard PM, Orr RM, Morgan SE, Murrer BA, Abrams MJ, Giandomenico CM, Cobbleigh T.
    Adv Enzyme Regul; 1991 Dec 15; 31():31-43. PubMed ID: 1877393
    [Abstract] [Full Text] [Related]

  • 19. Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.
    Kramer RA, Greene K, Ahmad S, Vistica DT.
    Cancer Res; 1987 Mar 15; 47(6):1593-7. PubMed ID: 3815359
    [Abstract] [Full Text] [Related]

  • 20. [Potentiation of cisplatin sensitivity of cisplatin-resistant human ovarian cancer cell lines by L-buthionine-S,R-sulfoximine].
    Kudoh K, Kita T, Hirata J, Ishii K, Hiramatsu H, Kikuchi Y, Nagata I.
    Nihon Sanka Fujinka Gakkai Zasshi; 1994 Jun 15; 46(6):525-32. PubMed ID: 8040625
    [Abstract] [Full Text] [Related]

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