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779 related items for PubMed ID: 8078905

  • 21. Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.
    Westwell-Roper CY, Ehses JA, Verchere CB.
    Diabetes; 2014 May; 63(5):1698-711. PubMed ID: 24222351
    [Abstract] [Full Text] [Related]

  • 22. Islet amyloid polypeptide (IAPP) secretion from pancreatic islets isolated from non-obese diabetic (NOD) mice.
    Karlsson E, Stridsberg M, Sandler S.
    Regul Pept; 1996 May 07; 63(1):39-45. PubMed ID: 8795087
    [Abstract] [Full Text] [Related]

  • 23. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT, Entrup L, Templin AT, Hogan MF, Mellati M, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2016 Oct 07; 59(10):2166-71. PubMed ID: 27393137
    [Abstract] [Full Text] [Related]

  • 24. Expression of human islet amyloid polypeptide/amylin impairs insulin secretion in mouse pancreatic beta cells.
    Tokuyama T, Yagui K, Yamaguchi T, Huang CI, Kuramoto N, Shimada F, Miyazaki J, Horie H, Saito Y, Makino H, Kanatsuka A.
    Metabolism; 1997 Sep 07; 46(9):1044-51. PubMed ID: 9284894
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  • 25. Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
    Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.
    Diabetologia; 1999 Apr 07; 42(4):427-34. PubMed ID: 10230646
    [Abstract] [Full Text] [Related]

  • 26. Amyloid formation in response to beta cell stress occurs in vitro, but not in vivo, in islets of transgenic mice expressing human islet amyloid polypeptide.
    Westermark G, Arora MB, Fox N, Carroll R, Chan SJ, Westermark P, Steiner DF.
    Mol Med; 1995 Jul 07; 1(5):542-53. PubMed ID: 8529120
    [Abstract] [Full Text] [Related]

  • 27. The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
    Vidal J, Verchere CB, Andrikopoulos S, Wang F, Hull RL, Cnop M, Olin KL, LeBoeuf RC, O'Brien KD, Chait A, Kahn SE.
    Diabetologia; 2003 Jan 07; 46(1):71-9. PubMed ID: 12637985
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  • 28. Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
    Castillo JJ, Aplin AC, Hackney DJ, Hogan MF, Esser N, Templin AT, Akter R, Kahn SE, Raleigh DP, Zraika S, Hull RL.
    Diabetologia; 2022 Oct 07; 65(10):1687-1700. PubMed ID: 35871651
    [Abstract] [Full Text] [Related]

  • 29. PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.
    Chen YC, Mains RE, Eipper BA, Hoffman BG, Czyzyk TA, Pintar JE, Verchere CB.
    Diabetologia; 2020 Mar 07; 63(3):561-576. PubMed ID: 31984442
    [Abstract] [Full Text] [Related]

  • 30. BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells.
    Oskarsson ME, Hermansson E, Wang Y, Welsh N, Presto J, Johansson J, Westermark GT.
    Proc Natl Acad Sci U S A; 2018 Mar 20; 115(12):E2752-E2761. PubMed ID: 29507232
    [Abstract] [Full Text] [Related]

  • 31. Islet amyloid polypeptide in pancreatic islets from type 2 diabetic subjects.
    Tomita T.
    Islets; 2012 Mar 20; 4(3):223-32. PubMed ID: 22847497
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  • 32. [Construction of transgenic mouse system expressing human islet amyloid polypeptide (IAPP)/amylin].
    Yagui K, Kanatsuka A, Makino H.
    Nihon Rinsho; 1994 Oct 20; 52(10):2746-50. PubMed ID: 7983808
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  • 33. Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
    Verchere CB, D'Alessio DA, Palmiter RD, Weir GC, Bonner-Weir S, Baskin DG, Kahn SE.
    Proc Natl Acad Sci U S A; 1996 Apr 16; 93(8):3492-6. PubMed ID: 8622964
    [Abstract] [Full Text] [Related]

  • 34. Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
    Law E, Lu S, Kieffer TJ, Warnock GL, Ao Z, Woo M, Marzban L.
    Diabetologia; 2010 Jul 16; 53(7):1415-27. PubMed ID: 20369225
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  • 35. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY, Chehroudi CA, Denroche HC, Courtade JA, Ehses JA, Verchere CB.
    Diabetologia; 2015 Mar 16; 58(3):575-85. PubMed ID: 25491100
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  • 36. Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.
    Paulsson JF, Andersson A, Westermark P, Westermark GT.
    Diabetologia; 2006 Jun 16; 49(6):1237-46. PubMed ID: 16570161
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  • 37. Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP.
    Westermark GT, Gebre-Medhin S, Steiner DF, Westermark P.
    Mol Med; 2000 Dec 16; 6(12):998-1007. PubMed ID: 11474116
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  • 38. Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
    Wong HY, Ahrén B, Lips CJ, Höppener JW, Sundler F.
    Regul Pept; 2003 May 15; 113(1-3):89-94. PubMed ID: 12686466
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  • 39. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep 15; 67(9):1897-1911. PubMed ID: 39245780
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  • 40. Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice.
    Wijesekara N, Gonçalves RA, Ahrens R, Ha K, De Felice FG, Fraser PE.
    J Pathol; 2021 Jul 15; 254(3):244-253. PubMed ID: 33797777
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