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Journal Abstract Search

177 related items for PubMed ID: 8081835

  • 1. Evaluation of functional analogs of CC-1065 and the duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e (C2BI) alkylation subunit.
    Boger DL, Johnson DS, Palanki MS, Kitos PA, Chang J, Dowell P.
    Bioorg Med Chem; 1993 Jul; 1(1):27-38. PubMed ID: 8081835
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  • 2. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity.
    Boger DL, Johnson DS, Yun W, Tarby CM.
    Bioorg Med Chem; 1994 Feb; 2(2):115-35. PubMed ID: 7922122
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  • 3. 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation.
    Boger DL, Yun W, Han N.
    Bioorg Med Chem; 1995 Nov; 3(11):1429-53. PubMed ID: 8634824
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  • 4. Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa.
    Boger DL, Hughes TV, Hedrick MP.
    J Org Chem; 2001 Apr 06; 66(7):2207-16. PubMed ID: 11281757
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  • 5. Synthesis and Properties of Substituted CBI Analogs of CC-1065 and the Duocarmycins Incorporating the 7-Methoxy-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (MCBI) Alkylation Subunit: Magnitude of Electronic Effects on the Functional Reactivity.
    Boger DL, McKie JA, Cai H, Cacciari B, Baraldi PG.
    J Org Chem; 1996 Mar 08; 61(5):1710-1729. PubMed ID: 11667041
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  • 6. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis.
    Boger DL, Santillán A, Searcey M, Brunette SR, Wolkenberg SE, Hedrick MP, Jin Q.
    J Org Chem; 2000 Jun 30; 65(13):4101-11. PubMed ID: 10866627
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  • 8. Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins.
    Boger DL, Brunette SR, Garbaccio RM.
    J Org Chem; 2001 Jul 27; 66(15):5163-73. PubMed ID: 11463270
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  • 9. Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit.
    Boger DL, Zarrinmayeh H, Munk SA, Kitos PA, Suntornwat O.
    Proc Natl Acad Sci U S A; 1991 Feb 15; 88(4):1431-5. PubMed ID: 1847523
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  • 10. CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit.
    Boger DL, Yun W, Cai H, Han N.
    Bioorg Med Chem; 1995 Jun 15; 3(6):761-7. PubMed ID: 7582954
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  • 15. CC-1065 CBI analogs: an example of enhancement of DNA alkylation efficiency through introduction of stabilizing electrostatic interactions.
    Boger DL, Yun W, Han N, Johnson DS.
    Bioorg Med Chem; 1995 Jun 15; 3(6):611-21. PubMed ID: 7582940
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  • 20. Asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).
    Lajiness JP, Boger DL.
    J Org Chem; 2011 Jan 21; 76(2):583-7. PubMed ID: 21192653
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