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Journal Abstract Search

128 related items for PubMed ID: 8083225

  • 1.
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  • 3. De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anti-cancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality.
    Bunting KD, Townsend AJ.
    J Biol Chem; 1996 May 17; 271(20):11884-90. PubMed ID: 8662658
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  • 5. Human breast adenocarcinoma MCF-7/0 cells electroporated with cytosolic class 3 aldehyde dehydrogenases obtained from tumor cells and a normal tissue exhibit differential sensitivity to mafosfamide.
    Sreerama L, Sladek NE.
    Drug Metab Dispos; 1995 Oct 17; 23(10):1080-4. PubMed ID: 8654195
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  • 6. Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance.
    Sreerama L, Sladek NE.
    Biochem Pharmacol; 1993 Jun 22; 45(12):2487-505. PubMed ID: 8328987
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  • 7. Intrinsic cellular resistance to oxazaphosphorines exhibited by a human colon carcinoma cell line expressing relatively large amounts of a class-3 aldehyde dehydrogenase.
    Rekha GK, Sreerama L, Sladek NE.
    Biochem Pharmacol; 1994 Nov 16; 48(10):1943-52. PubMed ID: 7986206
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  • 8. Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide.
    Moreb J, Schweder M, Suresh A, Zucali JR.
    Cancer Gene Ther; 1996 Nov 16; 3(1):24-30. PubMed ID: 8785707
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  • 9. Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acrolein.
    Bunting KD, Townsend AJ.
    Biochem Pharmacol; 1998 Jul 01; 56(1):31-9. PubMed ID: 9698086
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  • 11. Phenolic antioxidant-induced overexpression of class-3 aldehyde dehydrogenase and oxazaphosphorine-specific resistance.
    Sreerama L, Rekha GK, Sladek NE.
    Biochem Pharmacol; 1995 Mar 01; 49(5):669-75. PubMed ID: 7887982
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  • 12. Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3.
    Giorgianni F, Bridson PK, Sorrentino BP, Pohl J, Blakley RL.
    Biochem Pharmacol; 2000 Aug 01; 60(3):325-38. PubMed ID: 10856427
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  • 14. Multienzyme-mediated stable and transient multidrug resistance and collateral sensitivity induced by xenobiotics.
    Rekha GK, Sladek NE.
    Cancer Chemother Pharmacol; 1997 Aug 01; 40(3):215-24. PubMed ID: 9219504
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  • 15. Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase activity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell lines.
    Sladek NE, Landkamer GJ.
    Cancer Res; 1985 Apr 01; 45(4):1549-55. PubMed ID: 3978623
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  • 16. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
    Parajuli B, Georgiadis TM, Fishel ML, Hurley TD.
    Chembiochem; 2014 Mar 21; 15(5):701-12. PubMed ID: 24677340
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  • 17. Characterization of cytosolic aldehyde dehydrogenase from cyclophosphamide resistant L1210 cells.
    Russo JE, Hilton J.
    Cancer Res; 1988 Jun 01; 48(11):2963-8. PubMed ID: 3365687
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  • 18. Sensitivity of aldehyde dehydrogenases in murine tumor and hematopoietic progenitor cells to inhibition by chloral hydrate as determined by the ability of chloral hydrate to potentiate the cytotoxic action of mafosfamide.
    Maki PA, Sladek NE.
    Biochem Pharmacol; 1993 Jan 07; 45(1):231-9. PubMed ID: 8424816
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  • 19. The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance.
    Moreb JS, Ucar D, Han S, Amory JK, Goldstein AS, Ostmark B, Chang LJ.
    Chem Biol Interact; 2012 Jan 05; 195(1):52-60. PubMed ID: 22079344
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  • 20. Effect of aldehyde dehydrogenase inhibitors on the ex vivo sensitivity of human multipotent and committed hematopoietic progenitor cells and malignant blood cells to oxazaphosphorines.
    Kohn FR, Landkamer GJ, Manthey CL, Ramsay NK, Sladek NE.
    Cancer Res; 1987 Jun 15; 47(12):3180-5. PubMed ID: 3034402
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