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121 related items for PubMed ID: 8088366

  • 1. Structural requirements for the binding of fatty acids to 5-lipoxygenase-activating protein.
    Charleson S, Evans JF, Léger S, Perrier H, Prasit P, Wang Z, Vickers PJ.
    Eur J Pharmacol; 1994 May 17; 267(3):275-80. PubMed ID: 8088366
    [Abstract] [Full Text] [Related]

  • 2. A new class of leukotriene biosynthesis inhibitor: the development of MK-0591.
    Prasit P, Belley M, Blouin M, Brideau C, Chan C, Charleson S, Evans JF, Frenette R, Gauthier JY, Guay J.
    J Lipid Mediat; 1993 May 17; 6(1-3):239-44. PubMed ID: 8357985
    [Abstract] [Full Text] [Related]

  • 3. 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase.
    Abramovitz M, Wong E, Cox ME, Richardson CD, Li C, Vickers PJ.
    Eur J Biochem; 1993 Jul 01; 215(1):105-11. PubMed ID: 8344271
    [Abstract] [Full Text] [Related]

  • 4. Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor.
    Brideau C, Chan C, Charleson S, Denis D, Evans JF, Ford-Hutchinson AW, Fortin R, Gillard JW, Guay J, Guévremont D.
    Can J Physiol Pharmacol; 1992 Jun 01; 70(6):799-807. PubMed ID: 1330258
    [Abstract] [Full Text] [Related]

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  • 6. Studies of the inhibitory activity of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)-indol- 2-yl]-2,2-dimethyl propanoic acid) on arachidonic acid metabolism in human phagocytes.
    Ménard L, Laviolette M, Borgeat P.
    Can J Physiol Pharmacol; 1992 Jun 01; 70(6):808-13. PubMed ID: 1423024
    [Abstract] [Full Text] [Related]

  • 7. Characterization of a 5-lipoxygenase-activating protein binding assay: correlation of affinity for 5-lipoxygenase-activating protein with leukotriene synthesis inhibition.
    Charleson S, Prasit P, Léger S, Gillard JW, Vickers PJ, Mancini JA, Charleson P, Guay J, Ford-Hutchinson AW, Evans JF.
    Mol Pharmacol; 1992 May 01; 41(5):873-9. PubMed ID: 1588922
    [Abstract] [Full Text] [Related]

  • 8. The binding of leukotriene biosynthesis inhibitors to site-directed mutants of human 5-lipoxygenase-activating protein.
    Mancini JA, Coppolino MG, Klassen JH, Charleson S, Vickers PJ.
    Life Sci; 1994 May 01; 54(9):PL137-42. PubMed ID: 8114608
    [Abstract] [Full Text] [Related]

  • 9. Cellular oxygenation of 12-hydroxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid by 5-lipoxygenase is stimulated by 5-lipoxygenase-activating protein.
    Mancini JA, Waterman H, Riendeau D.
    J Biol Chem; 1998 Dec 04; 273(49):32842-7. PubMed ID: 9830031
    [Abstract] [Full Text] [Related]

  • 10. Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
    Ferguson AD, McKeever BM, Xu S, Wisniewski D, Miller DK, Yamin TT, Spencer RH, Chu L, Ujjainwalla F, Cunningham BR, Evans JF, Becker JW.
    Science; 2007 Jul 27; 317(5837):510-2. PubMed ID: 17600184
    [Abstract] [Full Text] [Related]

  • 11. Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.
    Hutchinson JH, Charleson S, Evans JF, Falgueyret JP, Hoogsteen K, Jones TR, Kargman S, Macdonald D, McFarlane CS, Nicholson DW.
    J Med Chem; 1995 Oct 27; 38(22):4538-47. PubMed ID: 7473582
    [Abstract] [Full Text] [Related]

  • 12. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors.
    Mancini JA, Prasit P, Coppolino MG, Charleson P, Leger S, Evans JF, Gillard JW, Vickers PJ.
    Mol Pharmacol; 1992 Feb 27; 41(2):267-72. PubMed ID: 1538707
    [Abstract] [Full Text] [Related]

  • 13. 5-lipoxygenase-activating protein is an arachidonate binding protein.
    Mancini JA, Abramovitz M, Cox ME, Wong E, Charleson S, Perrier H, Wang Z, Prasit P, Vickers PJ.
    FEBS Lett; 1993 Mar 08; 318(3):277-81. PubMed ID: 8440384
    [Abstract] [Full Text] [Related]

  • 14. Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors.
    Frenette R, Hutchinson JH, Léger S, Thérien M, Brideau C, Chan CC, Charleson S, Ethier D, Guay J, Jones TR, McAuliffe M, Piechuta H, Riendeau D, Tagari P, Girard Y.
    Bioorg Med Chem Lett; 1999 Aug 16; 9(16):2391-6. PubMed ID: 10476875
    [Abstract] [Full Text] [Related]

  • 15. Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors.
    Vickers PJ, Adam M, Charleson S, Coppolino MG, Evans JF, Mancini JA.
    Mol Pharmacol; 1992 Jul 16; 42(1):94-102. PubMed ID: 1635556
    [Abstract] [Full Text] [Related]

  • 16. 5-Lipoxygenase-activating protein homodimer in human neutrophils: evidence for a role in leukotriene biosynthesis.
    Plante H, Picard S, Mancini J, Borgeat P.
    Biochem J; 2006 Jan 01; 393(Pt 1):211-8. PubMed ID: 16144515
    [Abstract] [Full Text] [Related]

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  • 18. MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.
    Rouzer CA, Ford-Hutchinson AW, Morton HE, Gillard JW.
    J Biol Chem; 1990 Jan 25; 265(3):1436-42. PubMed ID: 2104841
    [Abstract] [Full Text] [Related]

  • 19. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis.
    Dixon RA, Diehl RE, Opas E, Rands E, Vickers PJ, Evans JF, Gillard JW, Miller DK.
    Nature; 1990 Jan 18; 343(6255):282-4. PubMed ID: 2300173
    [Abstract] [Full Text] [Related]

  • 20. 5-lipoxygenase and FLAP.
    Peters-Golden M, Brock TG.
    Prostaglandins Leukot Essent Fatty Acids; 2003 Jan 18; 69(2-3):99-109. PubMed ID: 12895592
    [Abstract] [Full Text] [Related]

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